FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005497797> ?p ?o ?g. }

• W2005497797 endingPage "e113394" @default.
• W2005497797 startingPage "e113394" @default.
• W2005497797 abstract "Background Vascular leak is the hallmark of severe dengue infections and leads to complications such as shock and multi-organ failure. Although many mediators have been implicated in the vascular leak in dengue, the role of sphingosine 1-phosphate (S1P) has not been investigated. Metholodology/Principal findings As S1P has been shown to be important in barrier integrity, we assessed the S1P levels in 28 patients with acute dengue and 12 healthy individuals. The S1P levels were significantly lower in patients with acute dengue (p = 0.002) and the levels in patients with grade IV dengue haemorrhagic fever (DHF) were significantly lower than those with dengue fever (p = 0.005). We then investigated the kinetics of S1P levels throughout the course of the illness in another 32 patients in serum samples obtained twice a day. We found that S1P levels were low throughout the course of illness and S1P levels were <0.5 µM in 12/23 patients with DHF when compared to 1/9 with DF. Conclusions/Significance As S1P has shown to be important in the endothelial barrier integrity and increases transendothelial resistance, low levels of S1P in acute dengue infection are likely to contribute to increased vascular permeability." @default.
• W2005497797 created "2016-06-24" @default.
• W2005497797 creator A5006304566 @default.
• W2005497797 creator A5011037605 @default.
• W2005497797 creator A5012402079 @default.
• W2005497797 creator A5016004337 @default.
• W2005497797 creator A5036950076 @default.
• W2005497797 creator A5050511886 @default.
• W2005497797 creator A5089478345 @default.
• W2005497797 date "2014-11-19" @default.
• W2005497797 modified "2023-10-17" @default.
• W2005497797 title "Sphingosine 1-Phosphate in Acute Dengue Infection" @default.
• W2005497797 cites W1867570846 @default.
• W2005497797 cites W1917851386 @default.
• W2005497797 cites W1984179269 @default.
• W2005497797 cites W1991558659 @default.
• W2005497797 cites W1995755756 @default.
• W2005497797 cites W1997232344 @default.
• W2005497797 cites W2008302729 @default.
• W2005497797 cites W2024514465 @default.
• W2005497797 cites W2026618323 @default.
• W2005497797 cites W2026677984 @default.
• W2005497797 cites W2030510738 @default.
• W2005497797 cites W2035541724 @default.
• W2005497797 cites W2038948806 @default.
• W2005497797 cites W2040235050 @default.
• W2005497797 cites W2068430855 @default.
• W2005497797 cites W2069114926 @default.
• W2005497797 cites W2076853373 @default.
• W2005497797 cites W2078150124 @default.
• W2005497797 cites W2095640342 @default.
• W2005497797 cites W2125879085 @default.
• W2005497797 cites W2131222241 @default.
• W2005497797 cites W2140081746 @default.
• W2005497797 cites W2148077696 @default.
• W2005497797 cites W2154886070 @default.
• W2005497797 cites W2155484006 @default.
• W2005497797 cites W2157824643 @default.
• W2005497797 cites W2164499679 @default.
• W2005497797 cites W2165338511 @default.
• W2005497797 cites W2166036680 @default.
• W2005497797 cites W2170557007 @default.
• W2005497797 cites W2171826138 @default.
• W2005497797 doi "https://doi.org/10.1371/journal.pone.0113394" @default.
• W2005497797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4237441" @default.
• W2005497797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25409037" @default.
• W2005497797 hasPublicationYear "2014" @default.
• W2005497797 type Work @default.
• W2005497797 sameAs 2005497797 @default.
• W2005497797 citedByCount "38" @default.
• W2005497797 countsByYear W20054977972015 @default.
• W2005497797 countsByYear W20054977972016 @default.
• W2005497797 countsByYear W20054977972017 @default.
• W2005497797 countsByYear W20054977972018 @default.
• W2005497797 countsByYear W20054977972019 @default.
• W2005497797 countsByYear W20054977972020 @default.
• W2005497797 countsByYear W20054977972021 @default.
• W2005497797 countsByYear W20054977972022 @default.
• W2005497797 countsByYear W20054977972023 @default.
• W2005497797 crossrefType "journal-article" @default.
• W2005497797 hasAuthorship W2005497797A5006304566 @default.
• W2005497797 hasAuthorship W2005497797A5011037605 @default.
• W2005497797 hasAuthorship W2005497797A5012402079 @default.
• W2005497797 hasAuthorship W2005497797A5016004337 @default.
• W2005497797 hasAuthorship W2005497797A5036950076 @default.
• W2005497797 hasAuthorship W2005497797A5050511886 @default.
• W2005497797 hasAuthorship W2005497797A5089478345 @default.
• W2005497797 hasBestOaLocation W20054977971 @default.
• W2005497797 hasConcept C113045295 @default.
• W2005497797 hasConcept C126322002 @default.
• W2005497797 hasConcept C170493617 @default.
• W2005497797 hasConcept C203014093 @default.
• W2005497797 hasConcept C2776596873 @default.
• W2005497797 hasConcept C2777628635 @default.
• W2005497797 hasConcept C2778384902 @default.
• W2005497797 hasConcept C2778703144 @default.
• W2005497797 hasConcept C2779635636 @default.
• W2005497797 hasConcept C533803919 @default.
• W2005497797 hasConcept C71924100 @default.
• W2005497797 hasConceptScore W2005497797C113045295 @default.
• W2005497797 hasConceptScore W2005497797C126322002 @default.
• W2005497797 hasConceptScore W2005497797C170493617 @default.
• W2005497797 hasConceptScore W2005497797C203014093 @default.
• W2005497797 hasConceptScore W2005497797C2776596873 @default.
• W2005497797 hasConceptScore W2005497797C2777628635 @default.
• W2005497797 hasConceptScore W2005497797C2778384902 @default.
• W2005497797 hasConceptScore W2005497797C2778703144 @default.
• W2005497797 hasConceptScore W2005497797C2779635636 @default.
• W2005497797 hasConceptScore W2005497797C533803919 @default.
• W2005497797 hasConceptScore W2005497797C71924100 @default.
• W2005497797 hasIssue "11" @default.
• W2005497797 hasLocation W20054977971 @default.
• W2005497797 hasLocation W20054977972 @default.
• W2005497797 hasLocation W20054977973 @default.
• W2005497797 hasLocation W20054977974 @default.
• W2005497797 hasLocation W20054977975 @default.
• W2005497797 hasOpenAccess W2005497797 @default.
• W2005497797 hasPrimaryLocation W20054977971 @default.

• next