Matches in SemOpenAlex for { <https://semopenalex.org/work/W200551735> ?p ?o ?g. }
- W200551735 endingPage "212" @default.
- W200551735 startingPage "202" @default.
- W200551735 abstract "The interaction between the thymus-derived lymphocyte (T cell) and its antigen-bearing target cell represents a model of contact-initiated intercellular communication. The unique feature of T cells is that they have evolved to distinguish self from nonself at the cellular level. That is, they do not recognize foreign antigens such as viruses as an entity alone, but rather they recognize aberrant neighboring cells as a perturbation of what they have “learned” as self. The basis of this self-perception is the conformation of complexes of peptides bound to a set of cell surface MHC (major histocompatibility complex) proteins unique to each individual. Activated T cells constantly sample neighboring cells in their environment for alterations in the conformation of these MHC complexes (Chang et al., 1979). Detection of “foreign” peptide-altered MHC complexes (e.g., on a virally infected cell) triggers the activation of a program of differentiated function within the T cell. In this chapter we will outline how the choice of antigen-bearing target cells and methods of assay have been used to explore the spectrum of functional T-cell activities resulting from the T cell-target interaction." @default.
- W200551735 created "2016-06-24" @default.
- W200551735 creator A5058401562 @default.
- W200551735 creator A5090261588 @default.
- W200551735 date "1993-01-01" @default.
- W200551735 modified "2023-10-17" @default.
- W200551735 title "Target Cell Events Initiated by T-Cell Attack" @default.
- W200551735 cites W126628608 @default.
- W200551735 cites W1482958179 @default.
- W200551735 cites W1493606186 @default.
- W200551735 cites W1501551519 @default.
- W200551735 cites W1505247385 @default.
- W200551735 cites W1505560953 @default.
- W200551735 cites W1515768041 @default.
- W200551735 cites W1529311244 @default.
- W200551735 cites W1532539996 @default.
- W200551735 cites W1534522578 @default.
- W200551735 cites W1536311055 @default.
- W200551735 cites W1548133871 @default.
- W200551735 cites W1564214284 @default.
- W200551735 cites W1582882171 @default.
- W200551735 cites W1588468987 @default.
- W200551735 cites W1589415602 @default.
- W200551735 cites W1592609289 @default.
- W200551735 cites W1597701963 @default.
- W200551735 cites W1612799267 @default.
- W200551735 cites W1642299321 @default.
- W200551735 cites W1668399282 @default.
- W200551735 cites W1757170295 @default.
- W200551735 cites W1763277209 @default.
- W200551735 cites W1871261170 @default.
- W200551735 cites W1872032514 @default.
- W200551735 cites W1894342370 @default.
- W200551735 cites W1937061404 @default.
- W200551735 cites W1966370175 @default.
- W200551735 cites W1967787805 @default.
- W200551735 cites W1973069846 @default.
- W200551735 cites W1976340479 @default.
- W200551735 cites W1976692354 @default.
- W200551735 cites W1983864186 @default.
- W200551735 cites W1984443531 @default.
- W200551735 cites W1984696190 @default.
- W200551735 cites W1985896777 @default.
- W200551735 cites W1986202661 @default.
- W200551735 cites W1989508434 @default.
- W200551735 cites W1991605327 @default.
- W200551735 cites W1993876791 @default.
- W200551735 cites W1996616758 @default.
- W200551735 cites W1999391883 @default.
- W200551735 cites W2007301952 @default.
- W200551735 cites W2009365954 @default.
- W200551735 cites W2013936027 @default.
- W200551735 cites W2014079018 @default.
- W200551735 cites W2015577939 @default.
- W200551735 cites W2020073768 @default.
- W200551735 cites W2020976163 @default.
- W200551735 cites W2026169598 @default.
- W200551735 cites W2026316042 @default.
- W200551735 cites W2032610393 @default.
- W200551735 cites W2034760582 @default.
- W200551735 cites W2065997722 @default.
- W200551735 cites W2072847344 @default.
- W200551735 cites W2080522935 @default.
- W200551735 cites W2118605877 @default.
- W200551735 cites W2129080097 @default.
- W200551735 cites W2129207936 @default.
- W200551735 cites W2134110351 @default.
- W200551735 cites W2160305298 @default.
- W200551735 cites W2164576152 @default.
- W200551735 cites W2165343206 @default.
- W200551735 cites W2165912118 @default.
- W200551735 cites W2167212594 @default.
- W200551735 cites W2169585497 @default.
- W200551735 cites W2170834275 @default.
- W200551735 cites W2178740741 @default.
- W200551735 cites W2189213585 @default.
- W200551735 cites W2266365863 @default.
- W200551735 cites W2312511255 @default.
- W200551735 cites W2324625211 @default.
- W200551735 cites W24819304 @default.
- W200551735 cites W2595376389 @default.
- W200551735 cites W284722034 @default.
- W200551735 cites W328083015 @default.
- W200551735 cites W4321829297 @default.
- W200551735 cites W4321829468 @default.
- W200551735 cites W4365787723 @default.
- W200551735 cites W632639492 @default.
- W200551735 cites W98709666 @default.
- W200551735 doi "https://doi.org/10.1007/978-1-4684-6814-4_19" @default.
- W200551735 hasPublicationYear "1993" @default.
- W200551735 type Work @default.
- W200551735 sameAs 200551735 @default.
- W200551735 citedByCount "0" @default.
- W200551735 crossrefType "book-chapter" @default.
- W200551735 hasAuthorship W200551735A5058401562 @default.
- W200551735 hasAuthorship W200551735A5090261588 @default.
- W200551735 hasConcept C147483822 @default.
- W200551735 hasConcept C1491633281 @default.