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• W2005528863 endingPage "1726" @default.
• W2005528863 startingPage "1722" @default.
• W2005528863 abstract "Type III secreted “effector” proteins of bacterial pathogens play central roles in virulence, yet are notoriously difficult to identify. We used an in vivo genetic screen to identify 13 effectors secreted by the type III apparatus (called Hrp, for “hypersensitive response and pathogenicity”) of the plant pathogen Pseudomonas syringae . Although sharing little overall homology, the amino-terminal regions of these effectors had strikingly similar amino acid compositions. This feature facilitated the bioinformatic prediction of 38 P. syringae effectors, including 15 previously unknown proteins. The secretion of two of these putative effectors was shown to be type III–dependent. Effectors showed high interstrain variation, supporting a role for some effectors in adaptation to different hosts." @default.
• W2005528863 created "2016-06-24" @default.
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• W2005528863 date "2002-03-01" @default.
• W2005528863 modified "2023-10-11" @default.
• W2005528863 title "A Functional Screen for the Type III (Hrp) Secretome of the Plant Pathogen <i>Pseudomonas syringae</i>" @default.
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• W2005528863 doi "https://doi.org/10.1126/science.295.5560.1722" @default.
• W2005528863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11872842" @default.
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