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- W2005531247 abstract "<h3>Importance</h3> Endophthalmitis caused by<i>Curvularia</i>is a rare condition seen after cataract surgery and trauma. The clinical course has not been described previously. <h3>Objective</h3> To examine the clinical course of 6 postoperative and trauma-related cases of<i>Curvularia</i>endophthalmitis. <h3>Design, Setting, and Participants</h3> Retrospective case series. We reviewed the archives of the microbiology laboratory of Bascom Palmer Eye Institute, a tertiary referral hospital, from January 1, 1980, through September 30, 2013, to identify cases of<i>Curvularia</i>endophthalmitis. Data collected included demographic information, the cause of endophthalmitis, presenting features, treatment course, the number of recurrences, the area of organism sequestration, and final visual outcome. <h3>Exposures</h3> Trauma and cataract surgery. <h3>Main Outcomes and Measures</h3> Times from the inciting event to presentation of symptoms, diagnosis, and eradication; visual acuity; and identification of the area of sequestration. <h3>Results</h3> We identified 6 patients with<i>Curvularia</i>endophthalmitis, including 5 who underwent cataract surgery and 1 after trauma. The diagnosis was established rapidly in the trauma case. In the postoperative cases, the time from the surgery to first symptoms ranged from 2 to 5 months; from the surgery to correct diagnosis, 7 to 24 months; and from the surgery to eradication, 8 to 27 months. Despite aggressive antifungal therapy, eradication of the infection could be achieved only by identification and removal of the nidus of sequestration. The median follow-up was 29.5 months. <h3>Conclusions and Relevance</h3> In cases of endophthalmitis caused by<i>Curvularia</i>, the diagnosis and treatment are often delayed, especially in postoperative cases. The eradication of the organism requires identification and removal of the nidi of sequestration." @default.
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- W2005531247 date "2014-09-01" @default.
- W2005531247 modified "2023-09-26" @default.
- W2005531247 title "Prolonged<i>Curvularia Endophthalmitis</i>Due to Organism Sequestration" @default.
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- W2005531247 doi "https://doi.org/10.1001/jamaophthalmol.2014.1069" @default.
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