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- W2005578877 abstract "Abstract Objectives/Hypothesis: We examined whether sufficient water intake is effective in the long‐term control of vertigo and hearing activity in patients with Meniere disease (MD) for whom conventional therapy has proven unsuccessful. Study Design: The authors conducted a time‐series study with historical control. Methods: Eighteen patients with MD in group 1 drank 35 mL/kg per day of water for 2 years. Twenty‐nine patients with MD treated with the conventional dietary and diuretic therapy for more than 2 years during 1992 to 1999 at the same hospital were enrolled in a historical control of group 2. Results: Patients in group 1 dramatically relieved vertigo and significantly improved in the hearing of the worst pure‐tone average of three frequencies (0.125, 0.25, and 0.5 kHz) (low PTA) during the last 6 months of the study period. In contrast, patients in group 2 became worse in both the four‐ (0.5, 1, 2, and 4 kHz) frequency PTA and the low PTA, although their vertigo did improve. The number of patients whose hearing were improved, unchanged, and worse were 4, 12, and 2 in group 1 and 2, 11, and 16 in group 2, respectively. Conclusion: Deliberate modulation of the intake of water may be the simplest and most cost‐effective medical treatment for patients with MD. Larger studies will be needed to confirm these results in a larger patient cohort." @default.
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- W2005578877 date "2006-08-01" @default.
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- W2005578877 title "Water May Cure Patients With Meniere Disease" @default.
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- W2005578877 doi "https://doi.org/10.1097/01.mlg.0000225904.78569.0c" @default.
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