FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005603265> ?p ?o ?g. }

• W2005603265 endingPage "124" @default.
• W2005603265 startingPage "114" @default.
• W2005603265 abstract "The cDNA sequence for insulin-like growth factor 2 (IGF-2) was determined from the liver of the marsupial brushtail possum (Trichosurus vulpecula) using reverse transcription followed by polymerase chain reaction (RT-PCR) with gene-specific primers. The 359 bp of possum sequence encompassed the mature peptide, 27 bp of the signal peptide, and 125 bp of the E-peptide. Alignment of the deduced amino acid sequence with those from other species indicated that the mature peptide was 71 amino acids in length, 4 amino acids longer than most other mammals. At both the nucleotide and amino acid levels there was a high degree of sequence identity with IGF-2 from other mammalian and nonmammalian species. Amino acid identity ranged from 94.4% with a variant form of human IGF-2 to 80.3% with zebrafinch IGF-2. Northern analysis revealed that radiolabeled possum IGF-2 cDNA hybridized to multiple transcripts in the liver of both adult possums and 150-day-old pouch young and that the overall level of expression was greater in pouch young. Semiquantitative RT-PCR with total RNA from liver samples of pouch young aged 12 to 150 days postpartum and adults confirmed that IGF-2 gene expression was two to three times more abundant in pouch young than in adults but there was no significant change in the level of expression during pouch life. Unlike other mammalian species, in which there is a decline in levels of liver IGF-2 gene expression around the time of birth, levels in the marsupial brushtail possum remain elevated for at least 150 days after birth. This suggests that the decline in liver IGF-2 expression in marsupials and eutherians occurs at a similar stage of development and may reflect a role for this growth factor during the postnatal growth and development of the marsupial." @default.
• W2005603265 created "2016-06-24" @default.
• W2005603265 creator A5029966359 @default.
• W2005603265 creator A5044512275 @default.
• W2005603265 creator A5083514880 @default.
• W2005603265 date "2001-01-01" @default.
• W2005603265 modified "2023-10-17" @default.
• W2005603265 title "Insulin-like Growth Factor 2 cDNA Cloning and Ontogeny of Gene Expression in the Liver of the Marsupial Brushtail Possum (Trichosurus vulpecula)" @default.
• W2005603265 cites W1495959646 @default.
• W2005603265 cites W1509427422 @default.
• W2005603265 cites W1511815713 @default.
• W2005603265 cites W1965996566 @default.
• W2005603265 cites W1969940363 @default.
• W2005603265 cites W1971147541 @default.
• W2005603265 cites W1982899676 @default.
• W2005603265 cites W1995549829 @default.
• W2005603265 cites W2004268799 @default.
• W2005603265 cites W2007573212 @default.
• W2005603265 cites W2026413371 @default.
• W2005603265 cites W2026870334 @default.
• W2005603265 cites W2029475375 @default.
• W2005603265 cites W2037737006 @default.
• W2005603265 cites W2038221793 @default.
• W2005603265 cites W2038938580 @default.
• W2005603265 cites W2043732011 @default.
• W2005603265 cites W2052523285 @default.
• W2005603265 cites W2053416990 @default.
• W2005603265 cites W2053449558 @default.
• W2005603265 cites W2062746841 @default.
• W2005603265 cites W2065298029 @default.
• W2005603265 cites W2080856575 @default.
• W2005603265 cites W2081139920 @default.
• W2005603265 cites W2082570571 @default.
• W2005603265 cites W2086980423 @default.
• W2005603265 cites W2088933777 @default.
• W2005603265 cites W2090403820 @default.
• W2005603265 cites W2102123572 @default.
• W2005603265 cites W2116286046 @default.
• W2005603265 cites W2130332764 @default.
• W2005603265 cites W2140121663 @default.
• W2005603265 cites W2151501517 @default.
• W2005603265 cites W2161763667 @default.
• W2005603265 cites W4247641001 @default.
• W2005603265 doi "https://doi.org/10.1006/gcen.2000.7581" @default.
• W2005603265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11161776" @default.
• W2005603265 hasPublicationYear "2001" @default.
• W2005603265 type Work @default.
• W2005603265 sameAs 2005603265 @default.
• W2005603265 citedByCount "3" @default.
• W2005603265 countsByYear W20056032652019 @default.
• W2005603265 crossrefType "journal-article" @default.
• W2005603265 hasAuthorship W2005603265A5029966359 @default.
• W2005603265 hasAuthorship W2005603265A5044512275 @default.
• W2005603265 hasAuthorship W2005603265A5083514880 @default.
• W2005603265 hasBestOaLocation W20056032651 @default.
• W2005603265 hasConcept C104317684 @default.
• W2005603265 hasConcept C105702510 @default.
• W2005603265 hasConcept C10858879 @default.
• W2005603265 hasConcept C150194340 @default.
• W2005603265 hasConcept C153911025 @default.
• W2005603265 hasConcept C167625842 @default.
• W2005603265 hasConcept C187882448 @default.
• W2005603265 hasConcept C19924922 @default.
• W2005603265 hasConcept C2777014246 @default.
• W2005603265 hasConcept C2777042810 @default.
• W2005603265 hasConcept C2780101441 @default.
• W2005603265 hasConcept C2910561697 @default.
• W2005603265 hasConcept C50724178 @default.
• W2005603265 hasConcept C515207424 @default.
• W2005603265 hasConcept C55493867 @default.
• W2005603265 hasConcept C84148353 @default.
• W2005603265 hasConcept C86803240 @default.
• W2005603265 hasConcept C90856448 @default.
• W2005603265 hasConceptScore W2005603265C104317684 @default.
• W2005603265 hasConceptScore W2005603265C105702510 @default.
• W2005603265 hasConceptScore W2005603265C10858879 @default.
• W2005603265 hasConceptScore W2005603265C150194340 @default.
• W2005603265 hasConceptScore W2005603265C153911025 @default.
• W2005603265 hasConceptScore W2005603265C167625842 @default.
• W2005603265 hasConceptScore W2005603265C187882448 @default.
• W2005603265 hasConceptScore W2005603265C19924922 @default.
• W2005603265 hasConceptScore W2005603265C2777014246 @default.
• W2005603265 hasConceptScore W2005603265C2777042810 @default.
• W2005603265 hasConceptScore W2005603265C2780101441 @default.
• W2005603265 hasConceptScore W2005603265C2910561697 @default.
• W2005603265 hasConceptScore W2005603265C50724178 @default.
• W2005603265 hasConceptScore W2005603265C515207424 @default.
• W2005603265 hasConceptScore W2005603265C55493867 @default.
• W2005603265 hasConceptScore W2005603265C84148353 @default.
• W2005603265 hasConceptScore W2005603265C86803240 @default.
• W2005603265 hasConceptScore W2005603265C90856448 @default.
• W2005603265 hasIssue "1" @default.
• W2005603265 hasLocation W20056032651 @default.
• W2005603265 hasLocation W20056032652 @default.
• W2005603265 hasOpenAccess W2005603265 @default.
• W2005603265 hasPrimaryLocation W20056032651 @default.
• W2005603265 hasRelatedWork W1984646339 @default.
• W2005603265 hasRelatedWork W2005603265 @default.

• next