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- W2005608001 abstract "Tumor lysis syndrome (TLS) is an oncologic emergency triggered by the rapid release of intracellular material from lysing malignant cells. Most common in rapidly growing hematologic malignancies, TLS has been reported in virtually every cancer type. Central to its pathogenesis is the rapid accumulation of uric acid derived from the breakdown of nucleic acids, which leads to kidney failure by various mechanisms. Kidney failure then limits the clearance of potassium, phosphorus, and uric acid leading to hyperkalemia, hyperphosphatemia, and secondary hypocalcemia, which can be fatal. Prevention of TLS may be more effective than treatment, and identification of at-risk individuals in whom to target preventative efforts remains a key research area. Herein, we discuss the pathophysiology, epidemiology, and treatment of TLS with an emphasis on the kidney manifestations of the disease." @default.
- W2005608001 created "2016-06-24" @default.
- W2005608001 creator A5025629807 @default.
- W2005608001 creator A5070205374 @default.
- W2005608001 date "2014-01-01" @default.
- W2005608001 modified "2023-10-16" @default.
- W2005608001 title "Tumor Lysis Syndrome: New Challenges and Recent Advances" @default.
- W2005608001 cites W1537752504 @default.
- W2005608001 cites W1554806549 @default.
- W2005608001 cites W1565888852 @default.
- W2005608001 cites W1605032945 @default.
- W2005608001 cites W1740327132 @default.
- W2005608001 cites W1754054048 @default.
- W2005608001 cites W1944363718 @default.
- W2005608001 cites W1964663305 @default.
- W2005608001 cites W1966551456 @default.
- W2005608001 cites W1967251991 @default.
- W2005608001 cites W1968008584 @default.
- W2005608001 cites W1972072288 @default.
- W2005608001 cites W1972695730 @default.
- W2005608001 cites W1972964840 @default.
- W2005608001 cites W1979867626 @default.
- W2005608001 cites W1984538669 @default.
- W2005608001 cites W1985749449 @default.
- W2005608001 cites W1986753580 @default.
- W2005608001 cites W1989895765 @default.
- W2005608001 cites W1991554408 @default.
- W2005608001 cites W1995553460 @default.
- W2005608001 cites W1998253273 @default.
- W2005608001 cites W1998470985 @default.
- W2005608001 cites W2006219673 @default.
- W2005608001 cites W20073424 @default.
- W2005608001 cites W2010672346 @default.
- W2005608001 cites W2015872854 @default.
- W2005608001 cites W2016170518 @default.
- W2005608001 cites W2016615524 @default.
- W2005608001 cites W2017587442 @default.
- W2005608001 cites W2020473773 @default.
- W2005608001 cites W2029808187 @default.
- W2005608001 cites W2030059967 @default.
- W2005608001 cites W2033941212 @default.
- W2005608001 cites W2036042881 @default.
- W2005608001 cites W2038672807 @default.
- W2005608001 cites W2039488099 @default.
- W2005608001 cites W2042746337 @default.
- W2005608001 cites W2046679370 @default.
- W2005608001 cites W2047246334 @default.
- W2005608001 cites W2048870340 @default.
- W2005608001 cites W2050000571 @default.
- W2005608001 cites W2050994521 @default.
- W2005608001 cites W2053406788 @default.
- W2005608001 cites W2054472950 @default.
- W2005608001 cites W2062814243 @default.
- W2005608001 cites W2063167399 @default.
- W2005608001 cites W2065956150 @default.
- W2005608001 cites W2066833271 @default.
- W2005608001 cites W2070862150 @default.
- W2005608001 cites W2071386060 @default.
- W2005608001 cites W2075505106 @default.
- W2005608001 cites W2077142615 @default.
- W2005608001 cites W2081362814 @default.
- W2005608001 cites W2083508836 @default.
- W2005608001 cites W2084627823 @default.
- W2005608001 cites W2084809606 @default.
- W2005608001 cites W2086024298 @default.
- W2005608001 cites W2090573786 @default.
- W2005608001 cites W2091838920 @default.
- W2005608001 cites W2095026923 @default.
- W2005608001 cites W2095998688 @default.
- W2005608001 cites W2097202501 @default.
- W2005608001 cites W2098453700 @default.
- W2005608001 cites W2108262590 @default.
- W2005608001 cites W2109333045 @default.
- W2005608001 cites W2114126778 @default.
- W2005608001 cites W2114419436 @default.
- W2005608001 cites W2116061272 @default.
- W2005608001 cites W2121256788 @default.
- W2005608001 cites W2121307284 @default.
- W2005608001 cites W2122479144 @default.
- W2005608001 cites W2134138207 @default.
- W2005608001 cites W2136052345 @default.
- W2005608001 cites W2136298697 @default.
- W2005608001 cites W2145816380 @default.
- W2005608001 cites W2155237074 @default.
- W2005608001 cites W2155240030 @default.
- W2005608001 cites W2162403132 @default.
- W2005608001 cites W2162513902 @default.
- W2005608001 cites W2165447689 @default.
- W2005608001 cites W2167545521 @default.
- W2005608001 cites W21933792 @default.
- W2005608001 cites W2433833805 @default.
- W2005608001 cites W4235770407 @default.
- W2005608001 cites W4246400434 @default.
- W2005608001 doi "https://doi.org/10.1053/j.ackd.2013.07.001" @default.
- W2005608001 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4017246" @default.
- W2005608001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24359983" @default.
- W2005608001 hasPublicationYear "2014" @default.
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