FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005619268> ?p ?o ?g. }

• W2005619268 endingPage "129" @default.
• W2005619268 startingPage "123" @default.
• W2005619268 abstract "The effectiveness of highly active antiretroviral therapy (HAART) in preventing disease progression can be negatively influenced by the high prevalence of substance use among patients. Here, we quantify the effect of history of injection drug use and alcoholism on virologic and immunologic response to HAART. Clinical and survey data, collected at the start of HAART and at the interview date, were based on the study Longitudinal Investigations into Supportive and Ancillary Health Services (LISA) in British Columbia, Canada. Substance use was a three-level categorical variable, combining information on history of alcohol dependence and of injection drug use, defined as: no history of alcohol and injection drug use; history of alcohol or injection drug use; and history of both alcohol and injection drug use. Virologic response (pVL) was defined by ≥2 log10 copy/mL drop in a viral load. Immunologic response was defined as an increase in CD4 cell count percent of ≥100%. We used cumulative logit modeling for ordinal responses to address our objective. Of the 537 HIV-infected patients, 112 (21%) were characterized as having a history of both alcohol and injection drug use, 173 (32%) were nonadherent (<95%), 196 (36%) had a CD4+/pVL+ (Best) response, 180 (34%) a CD4+/pVL− or a CD4− /pVL+ (Incomplete) response, and 161 (30%) a CD4− /pVL− (Worst) response. For individuals with history of both alcohol and injection drug use, the estimated probability of non-adherence was 0.61, and (0.15, 0.25, 0.60) of Best, Incomplete and Worse responses, respectively. Screening and detection of substance dependence will identify individuals at high-risk for nonadherence and ideally prevent their HIV disease from progressing to advanced stages where HIV disease can become difficult to manage." @default.
• W2005619268 created "2016-06-24" @default.
• W2005619268 creator A5040946922 @default.
• W2005619268 creator A5044801510 @default.
• W2005619268 creator A5061043962 @default.
• W2005619268 creator A5073679067 @default.
• W2005619268 creator A5074441717 @default.
• W2005619268 creator A5080431297 @default.
• W2005619268 creator A5085770040 @default.
• W2005619268 date "2013-06-14" @default.
• W2005619268 modified "2023-10-17" @default.
• W2005619268 title "The effect of history of injection drug use and alcoholism on HIV disease progression" @default.
• W2005619268 cites W1977664132 @default.
• W2005619268 cites W1977837314 @default.
• W2005619268 cites W1985206087 @default.
• W2005619268 cites W1990101902 @default.
• W2005619268 cites W2005528359 @default.
• W2005619268 cites W2009510016 @default.
• W2005619268 cites W2036142003 @default.
• W2005619268 cites W2053178989 @default.
• W2005619268 cites W2055135903 @default.
• W2005619268 cites W2069553488 @default.
• W2005619268 cites W2100628044 @default.
• W2005619268 cites W2120953033 @default.
• W2005619268 cites W2127693830 @default.
• W2005619268 cites W2148750104 @default.
• W2005619268 cites W2157133826 @default.
• W2005619268 cites W4254121089 @default.
• W2005619268 doi "https://doi.org/10.1080/09540121.2013.804900" @default.
• W2005619268 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3795995" @default.
• W2005619268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23767757" @default.
• W2005619268 hasPublicationYear "2013" @default.
• W2005619268 type Work @default.
• W2005619268 sameAs 2005619268 @default.
• W2005619268 citedByCount "18" @default.
• W2005619268 countsByYear W20056192682014 @default.
• W2005619268 countsByYear W20056192682015 @default.
• W2005619268 countsByYear W20056192682017 @default.
• W2005619268 countsByYear W20056192682018 @default.
• W2005619268 countsByYear W20056192682019 @default.
• W2005619268 countsByYear W20056192682020 @default.
• W2005619268 countsByYear W20056192682021 @default.
• W2005619268 countsByYear W20056192682022 @default.
• W2005619268 crossrefType "journal-article" @default.
• W2005619268 hasAuthorship W2005619268A5040946922 @default.
• W2005619268 hasAuthorship W2005619268A5044801510 @default.
• W2005619268 hasAuthorship W2005619268A5061043962 @default.
• W2005619268 hasAuthorship W2005619268A5073679067 @default.
• W2005619268 hasAuthorship W2005619268A5074441717 @default.
• W2005619268 hasAuthorship W2005619268A5080431297 @default.
• W2005619268 hasAuthorship W2005619268A5085770040 @default.
• W2005619268 hasBestOaLocation W20056192682 @default.
• W2005619268 hasConcept C126322002 @default.
• W2005619268 hasConcept C142462285 @default.
• W2005619268 hasConcept C151956035 @default.
• W2005619268 hasConcept C203014093 @default.
• W2005619268 hasConcept C206179267 @default.
• W2005619268 hasConcept C2780035454 @default.
• W2005619268 hasConcept C2780749119 @default.
• W2005619268 hasConcept C2781066024 @default.
• W2005619268 hasConcept C3013748606 @default.
• W2005619268 hasConcept C3017768595 @default.
• W2005619268 hasConcept C55493867 @default.
• W2005619268 hasConcept C71924100 @default.
• W2005619268 hasConcept C86803240 @default.
• W2005619268 hasConcept C98274493 @default.
• W2005619268 hasConceptScore W2005619268C126322002 @default.
• W2005619268 hasConceptScore W2005619268C142462285 @default.
• W2005619268 hasConceptScore W2005619268C151956035 @default.
• W2005619268 hasConceptScore W2005619268C203014093 @default.
• W2005619268 hasConceptScore W2005619268C206179267 @default.
• W2005619268 hasConceptScore W2005619268C2780035454 @default.
• W2005619268 hasConceptScore W2005619268C2780749119 @default.
• W2005619268 hasConceptScore W2005619268C2781066024 @default.
• W2005619268 hasConceptScore W2005619268C3013748606 @default.
• W2005619268 hasConceptScore W2005619268C3017768595 @default.
• W2005619268 hasConceptScore W2005619268C55493867 @default.
• W2005619268 hasConceptScore W2005619268C71924100 @default.
• W2005619268 hasConceptScore W2005619268C86803240 @default.
• W2005619268 hasConceptScore W2005619268C98274493 @default.
• W2005619268 hasIssue "1" @default.
• W2005619268 hasLocation W20056192681 @default.
• W2005619268 hasLocation W20056192682 @default.
• W2005619268 hasLocation W20056192683 @default.
• W2005619268 hasLocation W20056192684 @default.
• W2005619268 hasOpenAccess W2005619268 @default.
• W2005619268 hasPrimaryLocation W20056192681 @default.
• W2005619268 hasRelatedWork W1994292438 @default.
• W2005619268 hasRelatedWork W2017475382 @default.
• W2005619268 hasRelatedWork W2056857339 @default.
• W2005619268 hasRelatedWork W2082610484 @default.
• W2005619268 hasRelatedWork W2088562888 @default.
• W2005619268 hasRelatedWork W2096017738 @default.
• W2005619268 hasRelatedWork W2131050613 @default.
• W2005619268 hasRelatedWork W2564834386 @default.
• W2005619268 hasRelatedWork W4249572471 @default.
• W2005619268 hasRelatedWork W2159535789 @default.
• W2005619268 hasVolume "26" @default.

• next