FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005647400> ?p ?o ?g. }

• W2005647400 endingPage "i265" @default.
• W2005647400 startingPage "i257" @default.
• W2005647400 abstract "Template-based modeling, including homology modeling and protein threading, is the most reliable method for protein 3D structure prediction. However, alignment errors and template selection are still the main bottleneck for current template-base modeling methods, especially when proteins under consideration are distantly related.We present a novel context-specific alignment potential for protein threading, including alignment and template selection. Our alignment potential measures the log-odds ratio of one alignment being generated from two related proteins to being generated from two unrelated proteins, by integrating both local and global context-specific information. The local alignment potential quantifies how well one sequence residue can be aligned to one template residue based on context-specific information of the residues. The global alignment potential quantifies how well two sequence residues can be placed into two template positions at a given distance, again based on context-specific information. By accounting for correlation among a variety of protein features and making use of context-specific information, our alignment potential is much more sensitive than the widely used context-independent or profile-based scoring function. Experimental results confirm that our method generates significantly better alignments and threading results than the best profile-based methods on several large benchmarks. Our method works particularly well for distantly related proteins or proteins with sparse sequence profiles because of the effective integration of context-specific, structure and global information.http://raptorx.uchicago.edu/download/." @default.
• W2005647400 created "2016-06-24" @default.
• W2005647400 creator A5019398608 @default.
• W2005647400 creator A5073659320 @default.
• W2005647400 creator A5074269040 @default.
• W2005647400 creator A5090728366 @default.
• W2005647400 date "2013-06-21" @default.
• W2005647400 modified "2023-09-26" @default.
• W2005647400 title "Protein threading using context-specific alignment potential" @default.
• W2005647400 cites W1967538863 @default.
• W2005647400 cites W2003852785 @default.
• W2005647400 cites W2008016457 @default.
• W2005647400 cites W2008708467 @default.
• W2005647400 cites W2022058405 @default.
• W2005647400 cites W2033496784 @default.
• W2005647400 cites W2036149515 @default.
• W2005647400 cites W2040594319 @default.
• W2005647400 cites W2041966417 @default.
• W2005647400 cites W2051434435 @default.
• W2005647400 cites W2053069893 @default.
• W2005647400 cites W2063320403 @default.
• W2005647400 cites W2086765355 @default.
• W2005647400 cites W2090617952 @default.
• W2005647400 cites W2102245393 @default.
• W2005647400 cites W2109502170 @default.
• W2005647400 cites W2117451312 @default.
• W2005647400 cites W2125677968 @default.
• W2005647400 cites W2130357646 @default.
• W2005647400 cites W2142529984 @default.
• W2005647400 cites W2143210482 @default.
• W2005647400 cites W2144472358 @default.
• W2005647400 cites W2145268834 @default.
• W2005647400 cites W2147145103 @default.
• W2005647400 cites W2151831732 @default.
• W2005647400 cites W2160672912 @default.
• W2005647400 cites W2171546617 @default.
• W2005647400 cites W4241935390 @default.
• W2005647400 doi "https://doi.org/10.1093/bioinformatics/btt210" @default.
• W2005647400 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3694651" @default.
• W2005647400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23812991" @default.
• W2005647400 hasPublicationYear "2013" @default.
• W2005647400 type Work @default.
• W2005647400 sameAs 2005647400 @default.
• W2005647400 citedByCount "133" @default.
• W2005647400 countsByYear W20056474002013 @default.
• W2005647400 countsByYear W20056474002014 @default.
• W2005647400 countsByYear W20056474002015 @default.
• W2005647400 countsByYear W20056474002016 @default.
• W2005647400 countsByYear W20056474002017 @default.
• W2005647400 countsByYear W20056474002018 @default.
• W2005647400 countsByYear W20056474002019 @default.
• W2005647400 countsByYear W20056474002020 @default.
• W2005647400 countsByYear W20056474002021 @default.
• W2005647400 countsByYear W20056474002022 @default.
• W2005647400 countsByYear W20056474002023 @default.
• W2005647400 crossrefType "journal-article" @default.
• W2005647400 hasAuthorship W2005647400A5019398608 @default.
• W2005647400 hasAuthorship W2005647400A5073659320 @default.
• W2005647400 hasAuthorship W2005647400A5074269040 @default.
• W2005647400 hasAuthorship W2005647400A5090728366 @default.
• W2005647400 hasBestOaLocation W20056474001 @default.
• W2005647400 hasConcept C104317684 @default.
• W2005647400 hasConcept C151730666 @default.
• W2005647400 hasConcept C154945302 @default.
• W2005647400 hasConcept C167625842 @default.
• W2005647400 hasConcept C169627665 @default.
• W2005647400 hasConcept C180384323 @default.
• W2005647400 hasConcept C18051474 @default.
• W2005647400 hasConcept C181199279 @default.
• W2005647400 hasConcept C200307862 @default.
• W2005647400 hasConcept C2779343474 @default.
• W2005647400 hasConcept C41008148 @default.
• W2005647400 hasConcept C45475804 @default.
• W2005647400 hasConcept C45484198 @default.
• W2005647400 hasConcept C4668613 @default.
• W2005647400 hasConcept C47701112 @default.
• W2005647400 hasConcept C54355233 @default.
• W2005647400 hasConcept C55493867 @default.
• W2005647400 hasConcept C70721500 @default.
• W2005647400 hasConcept C86803240 @default.
• W2005647400 hasConcept C88031987 @default.
• W2005647400 hasConceptScore W2005647400C104317684 @default.
• W2005647400 hasConceptScore W2005647400C151730666 @default.
• W2005647400 hasConceptScore W2005647400C154945302 @default.
• W2005647400 hasConceptScore W2005647400C167625842 @default.
• W2005647400 hasConceptScore W2005647400C169627665 @default.
• W2005647400 hasConceptScore W2005647400C180384323 @default.
• W2005647400 hasConceptScore W2005647400C18051474 @default.
• W2005647400 hasConceptScore W2005647400C181199279 @default.
• W2005647400 hasConceptScore W2005647400C200307862 @default.
• W2005647400 hasConceptScore W2005647400C2779343474 @default.
• W2005647400 hasConceptScore W2005647400C41008148 @default.
• W2005647400 hasConceptScore W2005647400C45475804 @default.
• W2005647400 hasConceptScore W2005647400C45484198 @default.
• W2005647400 hasConceptScore W2005647400C4668613 @default.
• W2005647400 hasConceptScore W2005647400C47701112 @default.
• W2005647400 hasConceptScore W2005647400C54355233 @default.
• W2005647400 hasConceptScore W2005647400C55493867 @default.

• next