FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005655417> ?p ?o ?g. }

• W2005655417 endingPage "27" @default.
• W2005655417 startingPage "1" @default.
• W2005655417 abstract "There appears to be no dearth of mechanisms to explain spontaneous mutagenesis. In the case of base substitutions, data for bacteriophage T4 and especially for E. coli and S. cerevisiae suggest important roles in spontaneous mutagenesis for the error-prone repair of DNA damage (to produce mutations) and for error-free repair of DNA damage (to avoid mutagenesis). Data from the very limited number of studies on the subject suggest that about 50% of the spontaneous base substitutions in E. coli, and perhaps 90% in S. cerevisiae are due to error-prone DNA repair. On the other hand, spontaneous frameshifts and deletions seem to result from mechanisms involving recombination and replication. Spontaneous insertions have been shown to be important in the strongly polar inactivation of certain loci, but it is less important at other loci. Perhaps with continued study, the term spontaneous mutagenesis will be replaced by more specific terms such as 5-methylcytosine deamination mutagenesis, fatty acid oxidation mutagenesis, phenylalanine mutagenesis, and imprecise-recombination mutagenesis. While most studies have concentrated on mutator mutations, the most conclusive data for the actual source of spontaneous mutations have come from the study of antimutator mutations. Further study in this area, perhaps along with an understanding of chemical antimutagens, should be invaluable in clarifying the bases of spontaneous mutagenesis." @default.
• W2005655417 created "2016-06-24" @default.
• W2005655417 creator A5045746331 @default.
• W2005655417 creator A5084257328 @default.
• W2005655417 date "1985-07-01" @default.
• W2005655417 modified "2023-09-28" @default.
• W2005655417 title "Spontaneous mutagenesis: the roles of DNA repair, replication, and recombination" @default.
• W2005655417 cites W110262225 @default.
• W2005655417 cites W1447147799 @default.
• W2005655417 cites W1454967786 @default.
• W2005655417 cites W1484984821 @default.
• W2005655417 cites W1487666625 @default.
• W2005655417 cites W1488848625 @default.
• W2005655417 cites W1505453768 @default.
• W2005655417 cites W1509558837 @default.
• W2005655417 cites W1510420297 @default.
• W2005655417 cites W1516498317 @default.
• W2005655417 cites W1518934584 @default.
• W2005655417 cites W1530078985 @default.
• W2005655417 cites W1535660392 @default.
• W2005655417 cites W1539997589 @default.
• W2005655417 cites W1540318286 @default.
• W2005655417 cites W1546372489 @default.
• W2005655417 cites W1554627281 @default.
• W2005655417 cites W1568951733 @default.
• W2005655417 cites W1572168062 @default.
• W2005655417 cites W1572452525 @default.
• W2005655417 cites W1576021476 @default.
• W2005655417 cites W1586958619 @default.
• W2005655417 cites W1593010321 @default.
• W2005655417 cites W1594027581 @default.
• W2005655417 cites W1612116987 @default.
• W2005655417 cites W1674691036 @default.
• W2005655417 cites W1675235256 @default.
• W2005655417 cites W1693076167 @default.
• W2005655417 cites W1781792558 @default.
• W2005655417 cites W1810467512 @default.
• W2005655417 cites W1817150603 @default.
• W2005655417 cites W1847794240 @default.
• W2005655417 cites W1848310822 @default.
• W2005655417 cites W1850223967 @default.
• W2005655417 cites W1861951671 @default.
• W2005655417 cites W1862915326 @default.
• W2005655417 cites W1878364547 @default.
• W2005655417 cites W1894083071 @default.
• W2005655417 cites W1894790393 @default.
• W2005655417 cites W1896670299 @default.
• W2005655417 cites W1907834430 @default.
• W2005655417 cites W1940038678 @default.
• W2005655417 cites W1949047146 @default.
• W2005655417 cites W1963889242 @default.
• W2005655417 cites W1964083948 @default.
• W2005655417 cites W1964827967 @default.
• W2005655417 cites W1965818706 @default.
• W2005655417 cites W1966392871 @default.
• W2005655417 cites W1967128130 @default.
• W2005655417 cites W1967660799 @default.
• W2005655417 cites W1968724116 @default.
• W2005655417 cites W1969365479 @default.
• W2005655417 cites W1970779351 @default.
• W2005655417 cites W1971798784 @default.
• W2005655417 cites W1971845129 @default.
• W2005655417 cites W1974919501 @default.
• W2005655417 cites W1976100858 @default.
• W2005655417 cites W1976701806 @default.
• W2005655417 cites W1977607623 @default.
• W2005655417 cites W1977721810 @default.
• W2005655417 cites W1980933651 @default.
• W2005655417 cites W1981479013 @default.
• W2005655417 cites W1982557516 @default.
• W2005655417 cites W1983314059 @default.
• W2005655417 cites W1987972328 @default.
• W2005655417 cites W1989828735 @default.
• W2005655417 cites W1989847011 @default.
• W2005655417 cites W1990148696 @default.
• W2005655417 cites W1990785396 @default.
• W2005655417 cites W1991112301 @default.
• W2005655417 cites W1993275481 @default.
• W2005655417 cites W1995070276 @default.
• W2005655417 cites W1995749341 @default.
• W2005655417 cites W1997887065 @default.
• W2005655417 cites W1997953581 @default.
• W2005655417 cites W2001065545 @default.
• W2005655417 cites W2001894444 @default.
• W2005655417 cites W2002891103 @default.
• W2005655417 cites W2003754696 @default.
• W2005655417 cites W2004551381 @default.
• W2005655417 cites W2006276900 @default.
• W2005655417 cites W2008848226 @default.
• W2005655417 cites W2009043630 @default.
• W2005655417 cites W2010907597 @default.
• W2005655417 cites W2011421878 @default.
• W2005655417 cites W2013240923 @default.
• W2005655417 cites W2014353424 @default.
• W2005655417 cites W2014627718 @default.
• W2005655417 cites W2015408684 @default.
• W2005655417 cites W2016650294 @default.
• W2005655417 cites W2017280803 @default.

• next