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- W2005656449 abstract "Inflammation involves the activation of a highly coordinated gene expression program that is specific for the initial stimulus and occurs in a different manner in bystander parenchymal cells and professional immune system cells recruited to the inflamed site. Recent data demonstrate that developmental transcription factors like the macrophage fate-determining Pu.1 set the stage for the activity of ubiquitous transcription factors activated by inflammatory stimuli, like NF-kB, AP-1, and interferon regulatory factors (IRFs). The intersection of lineage-determining and stimulus-activated transcription factors at enhancers explains cell type specificity in inflammatory responses." @default.
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- W2005656449 date "2011-01-15" @default.
- W2005656449 modified "2023-10-16" @default.
- W2005656449 title "The genomic landscapes of inflammation" @default.
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- W2005656449 doi "https://doi.org/10.1101/gad.2018811" @default.
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