FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005668718> ?p ?o ?g. }

• W2005668718 endingPage "1257" @default.
• W2005668718 startingPage "1249" @default.
• W2005668718 abstract "Objective Ornithine carbamoyltransferase (OCT) is a liver-specific mitochondrial matrix enzyme and potential biomarker of liver fibrosis. This study investigated the OCT levels in patients with chronic liver disease with or without cirrhosis in order to assess the usefulness of OCT as a biomarker of cirrhosis. Methods The subjects included 440 Japanese patients with chronic liver disease and 80 control subjects. The patients were divided into two groups, those with and without cirrhosis, both of which were further stratified into high-OCT and low-OCT subgroups. Results In the non-cirrhosis group, the patients with non-alcoholic steatohepatitis (NASH), alcoholic liver disease, primary biliary cirrhosis and primary sclerosing cholangitis (PSC) comprised the high-OCT subgroup, while the patients with hepatitis B, hepatitis C and autoimmune hepatitis formed the low-OCT subgroup. There were significant differences in the OCT levels, OCT/aspartate aminotransferase ratios and OCT/alanine transaminase (ALT) ratios between these two subgroups (p<0.001). The same findings were observed in the cirrhosis group. The OCT levels were markedly higher in the cirrhosis group than in the non-cirrhosis group, particularly among the patients with PSC (p<0.001). The most useful biomarker for predicting cirrhosis was the OCT/ALT ratio in the patients with hepatitis C and NASH and the OCT level in patients with PSC. Conclusion The OCT level differs among patients with different chronic liver diseases. The role of OCT should be further evaluated in order to improve our understanding of the pathogenesis of these diseases. The OCT level is a useful surrogate marker of cirrhosis, particularly in PSC patients." @default.
• W2005668718 created "2016-06-24" @default.
• W2005668718 creator A5019629349 @default.
• W2005668718 creator A5037694830 @default.
• W2005668718 creator A5051185122 @default.
• W2005668718 creator A5055210740 @default.
• W2005668718 creator A5071426288 @default.
• W2005668718 creator A5084338218 @default.
• W2005668718 creator A5085435519 @default.
• W2005668718 creator A5088688541 @default.
• W2005668718 creator A5089650263 @default.
• W2005668718 creator A5090393270 @default.
• W2005668718 date "2014-01-01" @default.
• W2005668718 modified "2023-09-27" @default.
• W2005668718 title "Investigation of Ornithine Carbamoyltransferase as a Biomarker of Liver Cirrhosis" @default.
• W2005668718 cites W1969207321 @default.
• W2005668718 cites W1980062563 @default.
• W2005668718 cites W1991806532 @default.
• W2005668718 cites W2004574030 @default.
• W2005668718 cites W2019796203 @default.
• W2005668718 cites W2029707727 @default.
• W2005668718 cites W2051939090 @default.
• W2005668718 cites W2058648247 @default.
• W2005668718 cites W2065044288 @default.
• W2005668718 cites W2071689517 @default.
• W2005668718 cites W2409452754 @default.
• W2005668718 cites W2411278748 @default.
• W2005668718 cites W2742328320 @default.
• W2005668718 doi "https://doi.org/10.2169/internalmedicine.53.1944" @default.
• W2005668718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24930642" @default.
• W2005668718 hasPublicationYear "2014" @default.
• W2005668718 type Work @default.
• W2005668718 sameAs 2005668718 @default.
• W2005668718 citedByCount "6" @default.
• W2005668718 countsByYear W20056687182015 @default.
• W2005668718 countsByYear W20056687182016 @default.
• W2005668718 countsByYear W20056687182017 @default.
• W2005668718 countsByYear W20056687182018 @default.
• W2005668718 countsByYear W20056687182020 @default.
• W2005668718 crossrefType "journal-article" @default.
• W2005668718 hasAuthorship W2005668718A5019629349 @default.
• W2005668718 hasAuthorship W2005668718A5037694830 @default.
• W2005668718 hasAuthorship W2005668718A5051185122 @default.
• W2005668718 hasAuthorship W2005668718A5055210740 @default.
• W2005668718 hasAuthorship W2005668718A5071426288 @default.
• W2005668718 hasAuthorship W2005668718A5084338218 @default.
• W2005668718 hasAuthorship W2005668718A5085435519 @default.
• W2005668718 hasAuthorship W2005668718A5088688541 @default.
• W2005668718 hasAuthorship W2005668718A5089650263 @default.
• W2005668718 hasAuthorship W2005668718A5090393270 @default.
• W2005668718 hasBestOaLocation W20056687181 @default.
• W2005668718 hasConcept C126322002 @default.
• W2005668718 hasConcept C185592680 @default.
• W2005668718 hasConcept C2776029263 @default.
• W2005668718 hasConcept C2777075537 @default.
• W2005668718 hasConcept C2777203481 @default.
• W2005668718 hasConcept C2777214474 @default.
• W2005668718 hasConcept C2777575235 @default.
• W2005668718 hasConcept C2778772119 @default.
• W2005668718 hasConcept C2779102576 @default.
• W2005668718 hasConcept C2779134260 @default.
• W2005668718 hasConcept C2779478299 @default.
• W2005668718 hasConcept C2781197716 @default.
• W2005668718 hasConcept C55493867 @default.
• W2005668718 hasConcept C71924100 @default.
• W2005668718 hasConcept C90924648 @default.
• W2005668718 hasConceptScore W2005668718C126322002 @default.
• W2005668718 hasConceptScore W2005668718C185592680 @default.
• W2005668718 hasConceptScore W2005668718C2776029263 @default.
• W2005668718 hasConceptScore W2005668718C2777075537 @default.
• W2005668718 hasConceptScore W2005668718C2777203481 @default.
• W2005668718 hasConceptScore W2005668718C2777214474 @default.
• W2005668718 hasConceptScore W2005668718C2777575235 @default.
• W2005668718 hasConceptScore W2005668718C2778772119 @default.
• W2005668718 hasConceptScore W2005668718C2779102576 @default.
• W2005668718 hasConceptScore W2005668718C2779134260 @default.
• W2005668718 hasConceptScore W2005668718C2779478299 @default.
• W2005668718 hasConceptScore W2005668718C2781197716 @default.
• W2005668718 hasConceptScore W2005668718C55493867 @default.
• W2005668718 hasConceptScore W2005668718C71924100 @default.
• W2005668718 hasConceptScore W2005668718C90924648 @default.
• W2005668718 hasIssue "12" @default.
• W2005668718 hasLocation W20056687181 @default.
• W2005668718 hasLocation W20056687182 @default.
• W2005668718 hasOpenAccess W2005668718 @default.
• W2005668718 hasPrimaryLocation W20056687181 @default.
• W2005668718 hasRelatedWork W1575521550 @default.
• W2005668718 hasRelatedWork W1966147054 @default.
• W2005668718 hasRelatedWork W2006489894 @default.
• W2005668718 hasRelatedWork W2020532840 @default.
• W2005668718 hasRelatedWork W2469085901 @default.
• W2005668718 hasRelatedWork W3083928656 @default.
• W2005668718 hasRelatedWork W3125479117 @default.
• W2005668718 hasRelatedWork W3164959806 @default.
• W2005668718 hasRelatedWork W4281642480 @default.
• W2005668718 hasRelatedWork W4375863185 @default.
• W2005668718 hasVolume "53" @default.
• W2005668718 isParatext "false" @default.

• next