FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005669088> ?p ?o ?g. }

• W2005669088 endingPage "1162" @default.
• W2005669088 startingPage "1159" @default.
• W2005669088 abstract "Introduction: Lymphatic malformations (LM) are benign structural defects that can cause serious complications because of their size and location. Traditionally, surgical removal was the first treatment modality, but this could be associated with many complications and risks. Since Ogita introduced OK-432 (picibanil) in 1987 as a treatment method, this sclerosant has become popular. This paper is a review of the trials published so far on this topic. Patients and Methods: A literature search of English trials with 5 or more patients in it with LM who had never been treated before was done. The paper had to use the microcystic-macrocystic classification and have a mean follow-up of more than a year to be included in this review. Results were classified as excellent when the lesions show a regression of more than 90%, good when regression is more than 50%, and poor when shrinkage is less than 50% (this also includes no response at all). Results: Twenty-seven percent of microcystic LMs show an excellent result; 33%, a good result; and 40%, a poor result. Of the macrocystic LMs, 88% have excellent results. Recurrence rates vary from 5% to 8%. The adverse effects are mostly mild. Discussion: Most trials have a short follow-up; therefore, there are uncertainties when it comes to cure and regression. Mostly, the adverse effects of OK-432 are trivial and disappear after a week, but the need for a temporary tracheostomy has been described. Screening for allergic reactions to penicilline is needed, with the risk of anaphylactic shock in mind. It is difficult to compare the different techniques used by the authors, and none of the trials included in this study are randomized controlled trials; most are retrospective and were so-called level 4 studies. Conclusions: This review demonstrates that OK-432 is an effective way to treat LM. Because of a possible risk of airway obstruction, treatment should always take place in specialized treatment facilities. Macrocystic lesions show a better response to OK-432 treatment than microcystic lesions. Serious complications with OK-432 are infrequent, and this type of sclerotherapy seems to have no influence on future surgery. We therefore suggest the use of OK-432 as an effective first-line treatment of LMs." @default.
• W2005669088 created "2016-06-24" @default.
• W2005669088 creator A5004964571 @default.
• W2005669088 creator A5012541866 @default.
• W2005669088 creator A5053287697 @default.
• W2005669088 creator A5090630130 @default.
• W2005669088 date "2009-07-01" @default.
• W2005669088 modified "2023-09-23" @default.
• W2005669088 title "Treatment of Lymphatic Malformations With OK-432 (Picibanil)" @default.
• W2005669088 cites W1970046362 @default.
• W2005669088 cites W1979172623 @default.
• W2005669088 cites W1980916211 @default.
• W2005669088 cites W1984711946 @default.
• W2005669088 cites W1987713703 @default.
• W2005669088 cites W1992444509 @default.
• W2005669088 cites W1997742820 @default.
• W2005669088 cites W2013337718 @default.
• W2005669088 cites W2013666706 @default.
• W2005669088 cites W2026344501 @default.
• W2005669088 cites W2027211235 @default.
• W2005669088 cites W2063851044 @default.
• W2005669088 cites W2067015853 @default.
• W2005669088 cites W2077912340 @default.
• W2005669088 cites W2085407815 @default.
• W2005669088 cites W2086827853 @default.
• W2005669088 cites W2112207264 @default.
• W2005669088 cites W2123631659 @default.
• W2005669088 cites W2127436573 @default.
• W2005669088 cites W2143312543 @default.
• W2005669088 cites W2145682933 @default.
• W2005669088 cites W2148072374 @default.
• W2005669088 cites W2397773922 @default.
• W2005669088 cites W4232552710 @default.
• W2005669088 cites W1963915575 @default.
• W2005669088 doi "https://doi.org/10.1097/scs.0b013e3181abb249" @default.
• W2005669088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19553857" @default.
• W2005669088 hasPublicationYear "2009" @default.
• W2005669088 type Work @default.
• W2005669088 sameAs 2005669088 @default.
• W2005669088 citedByCount "81" @default.
• W2005669088 countsByYear W20056690882012 @default.
• W2005669088 countsByYear W20056690882013 @default.
• W2005669088 countsByYear W20056690882014 @default.
• W2005669088 countsByYear W20056690882015 @default.
• W2005669088 countsByYear W20056690882016 @default.
• W2005669088 countsByYear W20056690882017 @default.
• W2005669088 countsByYear W20056690882018 @default.
• W2005669088 countsByYear W20056690882019 @default.
• W2005669088 countsByYear W20056690882020 @default.
• W2005669088 countsByYear W20056690882021 @default.
• W2005669088 countsByYear W20056690882022 @default.
• W2005669088 countsByYear W20056690882023 @default.
• W2005669088 crossrefType "journal-article" @default.
• W2005669088 hasAuthorship W2005669088A5004964571 @default.
• W2005669088 hasAuthorship W2005669088A5012541866 @default.
• W2005669088 hasAuthorship W2005669088A5053287697 @default.
• W2005669088 hasAuthorship W2005669088A5090630130 @default.
• W2005669088 hasConcept C126322002 @default.
• W2005669088 hasConcept C141071460 @default.
• W2005669088 hasConcept C197934379 @default.
• W2005669088 hasConcept C203014093 @default.
• W2005669088 hasConcept C207480886 @default.
• W2005669088 hasConcept C2775933838 @default.
• W2005669088 hasConcept C2994163677 @default.
• W2005669088 hasConcept C71924100 @default.
• W2005669088 hasConceptScore W2005669088C126322002 @default.
• W2005669088 hasConceptScore W2005669088C141071460 @default.
• W2005669088 hasConceptScore W2005669088C197934379 @default.
• W2005669088 hasConceptScore W2005669088C203014093 @default.
• W2005669088 hasConceptScore W2005669088C207480886 @default.
• W2005669088 hasConceptScore W2005669088C2775933838 @default.
• W2005669088 hasConceptScore W2005669088C2994163677 @default.
• W2005669088 hasConceptScore W2005669088C71924100 @default.
• W2005669088 hasIssue "4" @default.
• W2005669088 hasLocation W20056690881 @default.
• W2005669088 hasLocation W20056690882 @default.
• W2005669088 hasOpenAccess W2005669088 @default.
• W2005669088 hasPrimaryLocation W20056690881 @default.
• W2005669088 hasRelatedWork W1586374228 @default.
• W2005669088 hasRelatedWork W2003938723 @default.
• W2005669088 hasRelatedWork W2047967234 @default.
• W2005669088 hasRelatedWork W2118496982 @default.
• W2005669088 hasRelatedWork W2364998975 @default.
• W2005669088 hasRelatedWork W2369162477 @default.
• W2005669088 hasRelatedWork W2401939935 @default.
• W2005669088 hasRelatedWork W2439875401 @default.
• W2005669088 hasRelatedWork W4238867864 @default.
• W2005669088 hasRelatedWork W2525756941 @default.
• W2005669088 hasVolume "20" @default.
• W2005669088 isParatext "false" @default.
• W2005669088 isRetracted "false" @default.
• W2005669088 magId "2005669088" @default.
• W2005669088 workType "article" @default.