Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005669114> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2005669114 endingPage "3228" @default.
- W2005669114 startingPage "3224" @default.
- W2005669114 abstract "To investigate the relationship between the structure of curdlan sulfate with β-[1→3]-d-glucan as main chain and the anti-HIV activity, three regioselective substituted curdlan sulfates (CS's), i.e., CS having sulfate groups at all C6 and some C2 positions (62S), CS having sulfate groups at all C4 and some C2 positions (42S), and CS having sulfate groups at some C6, C4, and C2 positions (642S), were synthesized. Their structures were characterized by 13C NMR spectroscopy. These curdlan sulfates had number average molecular weights in the range 6.2 × 103 to 10.8 × 103. For the various curdlan sulfates, anti-HIV activities and anticoagulant activities were assayed in vitro. It was revealed that these curdlan sulfates showed high anti-HIV activities in the EC50 range 0.04−0.4 μg/mL when the degree of sulfation was more than 1.3, and low cytotoxicities as well as low blood anticoagulant activities. Furthermore, it was found that the anti-HIV activity of curdlan sulfates depended on the degree of sulfation but not on the position of sulfate groups." @default.
- W2005669114 created "2016-06-24" @default.
- W2005669114 creator A5017615239 @default.
- W2005669114 creator A5020401798 @default.
- W2005669114 creator A5049447403 @default.
- W2005669114 creator A5057210004 @default.
- W2005669114 creator A5074905580 @default.
- W2005669114 creator A5086534497 @default.
- W2005669114 creator A5088904531 @default.
- W2005669114 date "1997-06-01" @default.
- W2005669114 modified "2023-10-14" @default.
- W2005669114 title "Synthesis of Regioselective Substituted Curdlan Sulfates with Medium Molecular Weights and Their Specific Anti-HIV-1 Activities" @default.
- W2005669114 cites W1973398091 @default.
- W2005669114 cites W1979341342 @default.
- W2005669114 cites W1985323085 @default.
- W2005669114 cites W1988157903 @default.
- W2005669114 cites W1988647121 @default.
- W2005669114 cites W1991205666 @default.
- W2005669114 cites W2003122930 @default.
- W2005669114 cites W2011630381 @default.
- W2005669114 cites W2024478524 @default.
- W2005669114 cites W2035489589 @default.
- W2005669114 cites W2035938088 @default.
- W2005669114 cites W2055060143 @default.
- W2005669114 cites W2057461438 @default.
- W2005669114 cites W2062212664 @default.
- W2005669114 cites W2063825413 @default.
- W2005669114 cites W2070458768 @default.
- W2005669114 cites W2075131321 @default.
- W2005669114 cites W2085459671 @default.
- W2005669114 cites W2086186867 @default.
- W2005669114 cites W2086462809 @default.
- W2005669114 cites W2157876263 @default.
- W2005669114 cites W2158179663 @default.
- W2005669114 doi "https://doi.org/10.1021/ma961711d" @default.
- W2005669114 hasPublicationYear "1997" @default.
- W2005669114 type Work @default.
- W2005669114 sameAs 2005669114 @default.
- W2005669114 citedByCount "40" @default.
- W2005669114 countsByYear W20056691142012 @default.
- W2005669114 countsByYear W20056691142013 @default.
- W2005669114 countsByYear W20056691142014 @default.
- W2005669114 countsByYear W20056691142015 @default.
- W2005669114 countsByYear W20056691142017 @default.
- W2005669114 countsByYear W20056691142018 @default.
- W2005669114 countsByYear W20056691142021 @default.
- W2005669114 countsByYear W20056691142022 @default.
- W2005669114 countsByYear W20056691142023 @default.
- W2005669114 crossrefType "journal-article" @default.
- W2005669114 hasAuthorship W2005669114A5017615239 @default.
- W2005669114 hasAuthorship W2005669114A5020401798 @default.
- W2005669114 hasAuthorship W2005669114A5049447403 @default.
- W2005669114 hasAuthorship W2005669114A5057210004 @default.
- W2005669114 hasAuthorship W2005669114A5074905580 @default.
- W2005669114 hasAuthorship W2005669114A5086534497 @default.
- W2005669114 hasAuthorship W2005669114A5088904531 @default.
- W2005669114 hasConcept C100817775 @default.
- W2005669114 hasConcept C155138218 @default.
- W2005669114 hasConcept C161790260 @default.
- W2005669114 hasConcept C178790620 @default.
- W2005669114 hasConcept C185592680 @default.
- W2005669114 hasConcept C2778343803 @default.
- W2005669114 hasConcept C2779929572 @default.
- W2005669114 hasConcept C55493867 @default.
- W2005669114 hasConcept C59759590 @default.
- W2005669114 hasConcept C71240020 @default.
- W2005669114 hasConceptScore W2005669114C100817775 @default.
- W2005669114 hasConceptScore W2005669114C155138218 @default.
- W2005669114 hasConceptScore W2005669114C161790260 @default.
- W2005669114 hasConceptScore W2005669114C178790620 @default.
- W2005669114 hasConceptScore W2005669114C185592680 @default.
- W2005669114 hasConceptScore W2005669114C2778343803 @default.
- W2005669114 hasConceptScore W2005669114C2779929572 @default.
- W2005669114 hasConceptScore W2005669114C55493867 @default.
- W2005669114 hasConceptScore W2005669114C59759590 @default.
- W2005669114 hasConceptScore W2005669114C71240020 @default.
- W2005669114 hasIssue "11" @default.
- W2005669114 hasLocation W20056691141 @default.
- W2005669114 hasOpenAccess W2005669114 @default.
- W2005669114 hasPrimaryLocation W20056691141 @default.
- W2005669114 hasRelatedWork W1968452702 @default.
- W2005669114 hasRelatedWork W1981122053 @default.
- W2005669114 hasRelatedWork W2019107044 @default.
- W2005669114 hasRelatedWork W2033355912 @default.
- W2005669114 hasRelatedWork W2139056474 @default.
- W2005669114 hasRelatedWork W2949990076 @default.
- W2005669114 hasRelatedWork W2950078743 @default.
- W2005669114 hasRelatedWork W2951495520 @default.
- W2005669114 hasRelatedWork W2952437957 @default.
- W2005669114 hasRelatedWork W3005514996 @default.
- W2005669114 hasVolume "30" @default.
- W2005669114 isParatext "false" @default.
- W2005669114 isRetracted "false" @default.
- W2005669114 magId "2005669114" @default.
- W2005669114 workType "article" @default.