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- W2005672080 abstract "Methylcholanthrene and phenobarbital administered in vivo stimulate the RNA polymerase activity of isolated rat liver nuclei. The stimulation is observed in the absence and presence of ammonium sulfate. DNA isolated from either methylcholanthrene or phenobarbital treated rats or control rats has the same template activity for RNA synthesis when measured with Micrococcus lysodeikticus RNA polymerase. Aflatoxin, a potent liver carcinogen and inhibitor of enzyme induction, markedly decreases RNA polymerase activity of rat liver nuclei. A 40–70% inhibition is observed within 15 min to 2 hr after aflatoxin is administered." @default.
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- W2005672080 date "1967-01-01" @default.
- W2005672080 modified "2023-09-28" @default.
- W2005672080 title "The effect of methylchlanthrene, phenobarbital and aflatoxin on RNA polymerase of rat liver" @default.
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- W2005672080 doi "https://doi.org/10.1016/0065-2571(67)90027-1" @default.
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