Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005678506> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2005678506 endingPage "242" @default.
- W2005678506 startingPage "231" @default.
- W2005678506 abstract "In pig and sheep thyroid, the arachidonate content of phosphatidylinositol (14.3–17.5%) is much higher than in the other phospholipids. In the thyroid, phosphatidylinositol seems to play an important role in the biosynthesis of prostaglandins. In neutral thyroid lipids, the arachidonate content is much higher in diacylglycerols (15.8%) than in monoacylglycerols (2.9%) or triacylglycerols (4.2%). However, the most important pool of esterified arachidonate is triacylglycerols (1030 nmol of arachidonate/g tissue). Arachidonate represents a very small part of total free fatty acids measured in the presence of albumin and indomethacin (0.65% or 16.4 nmol/g tissue). Thyrotropin (50 munits/ml) causes after 1 h a 2-fold increase in the level of free arachidonate (37.3 nmol/g tissue). Pig thyroid slices rapidly take up [14C] arachidonate and incorporate it into neutral lipids and phospholipids. Specific activity of phosphatidylinositol is 3-fold higher than that of phosphatidylcholine after an hour incubation. Specific activity of diacylglycerols is 8-fold higher than that of triacylglycerols. Thyrotropin (50 munits/ml) causes a significant decrease (32–33%) of incorporation of radioactivity in lipids as compared with standard incubation. This result is compatible with the isotopic dilution of the labeled [14C]arachidonate by nonradioactive arachidonate liberated in the incubation medium under thyrotropin action. Slices and homogenates of pig thyroid weakly convert [14C] arachidonate to prostaglandins E2 and F2α (1–2%). Thyrotropin (50 munits/ml) always diminishes the conversion of radioactivity to prostaglandins as compared with standard incubation. This result is compatible with the above-mentioned hypothesis." @default.
- W2005678506 created "2016-06-24" @default.
- W2005678506 creator A5003136625 @default.
- W2005678506 creator A5007752063 @default.
- W2005678506 date "1977-04-01" @default.
- W2005678506 modified "2023-10-18" @default.
- W2005678506 title "Incorporation of [14]arachidonate in pig thyroid lipids and prostaglandins" @default.
- W2005678506 cites W1890547526 @default.
- W2005678506 cites W1924509623 @default.
- W2005678506 cites W1967243439 @default.
- W2005678506 cites W1972382993 @default.
- W2005678506 cites W1979065558 @default.
- W2005678506 cites W1989854695 @default.
- W2005678506 cites W1996003247 @default.
- W2005678506 cites W2014080068 @default.
- W2005678506 cites W2018373835 @default.
- W2005678506 cites W2019152483 @default.
- W2005678506 cites W2023271309 @default.
- W2005678506 cites W2029355403 @default.
- W2005678506 cites W2033574467 @default.
- W2005678506 cites W2037767704 @default.
- W2005678506 cites W2039782998 @default.
- W2005678506 cites W2057083611 @default.
- W2005678506 cites W2059705078 @default.
- W2005678506 cites W2060638992 @default.
- W2005678506 cites W2077208516 @default.
- W2005678506 cites W2114755767 @default.
- W2005678506 cites W2135247601 @default.
- W2005678506 cites W2141974801 @default.
- W2005678506 cites W2148147361 @default.
- W2005678506 cites W2154457535 @default.
- W2005678506 cites W2189283791 @default.
- W2005678506 cites W2207533602 @default.
- W2005678506 cites W2311118231 @default.
- W2005678506 doi "https://doi.org/10.1016/0005-2760(77)90059-5" @default.
- W2005678506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/870056" @default.
- W2005678506 hasPublicationYear "1977" @default.
- W2005678506 type Work @default.
- W2005678506 sameAs 2005678506 @default.
- W2005678506 citedByCount "31" @default.
- W2005678506 crossrefType "journal-article" @default.
- W2005678506 hasAuthorship W2005678506A5003136625 @default.
- W2005678506 hasAuthorship W2005678506A5007752063 @default.
- W2005678506 hasConcept C126322002 @default.
- W2005678506 hasConcept C134018914 @default.
- W2005678506 hasConcept C181199279 @default.
- W2005678506 hasConcept C184235292 @default.
- W2005678506 hasConcept C185592680 @default.
- W2005678506 hasConcept C25642318 @default.
- W2005678506 hasConcept C2776330855 @default.
- W2005678506 hasConcept C2778078955 @default.
- W2005678506 hasConcept C2778918659 @default.
- W2005678506 hasConcept C2780610907 @default.
- W2005678506 hasConcept C2780664492 @default.
- W2005678506 hasConcept C41625074 @default.
- W2005678506 hasConcept C526584372 @default.
- W2005678506 hasConcept C55493867 @default.
- W2005678506 hasConcept C71924100 @default.
- W2005678506 hasConcept C86803240 @default.
- W2005678506 hasConceptScore W2005678506C126322002 @default.
- W2005678506 hasConceptScore W2005678506C134018914 @default.
- W2005678506 hasConceptScore W2005678506C181199279 @default.
- W2005678506 hasConceptScore W2005678506C184235292 @default.
- W2005678506 hasConceptScore W2005678506C185592680 @default.
- W2005678506 hasConceptScore W2005678506C25642318 @default.
- W2005678506 hasConceptScore W2005678506C2776330855 @default.
- W2005678506 hasConceptScore W2005678506C2778078955 @default.
- W2005678506 hasConceptScore W2005678506C2778918659 @default.
- W2005678506 hasConceptScore W2005678506C2780610907 @default.
- W2005678506 hasConceptScore W2005678506C2780664492 @default.
- W2005678506 hasConceptScore W2005678506C41625074 @default.
- W2005678506 hasConceptScore W2005678506C526584372 @default.
- W2005678506 hasConceptScore W2005678506C55493867 @default.
- W2005678506 hasConceptScore W2005678506C71924100 @default.
- W2005678506 hasConceptScore W2005678506C86803240 @default.
- W2005678506 hasIssue "1" @default.
- W2005678506 hasLocation W20056785061 @default.
- W2005678506 hasLocation W20056785062 @default.
- W2005678506 hasOpenAccess W2005678506 @default.
- W2005678506 hasPrimaryLocation W20056785061 @default.
- W2005678506 hasRelatedWork W1580876138 @default.
- W2005678506 hasRelatedWork W1966370012 @default.
- W2005678506 hasRelatedWork W1979891544 @default.
- W2005678506 hasRelatedWork W1980929094 @default.
- W2005678506 hasRelatedWork W1982014927 @default.
- W2005678506 hasRelatedWork W1991973066 @default.
- W2005678506 hasRelatedWork W2018935255 @default.
- W2005678506 hasRelatedWork W2039550083 @default.
- W2005678506 hasRelatedWork W2053995479 @default.
- W2005678506 hasRelatedWork W2062209858 @default.
- W2005678506 hasVolume "487" @default.
- W2005678506 isParatext "false" @default.
- W2005678506 isRetracted "false" @default.
- W2005678506 magId "2005678506" @default.
- W2005678506 workType "article" @default.