FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005681750> ?p ?o ?g. }

• W2005681750 endingPage "254" @default.
• W2005681750 startingPage "245" @default.
• W2005681750 abstract "1. Mass fragmentography was used to measure the tissue content and release of acetylcholine (ACh) by frog sartorius muscles, which had been previously treated with an irreversible cholinesterase inhibitor. The frequency of miniature end-plate currents (m.e.p.c.s) was also measured. 2. Exposure of muscles for 15 min to 2 mM-LaCl3 resulted in a large release of ACh which subsided to low levels after 1 h. About 4 h later treatment with 50 mM-KCl, or with the calcium ionophore A 23187, or with a second dose of LaCl3, all failed to augment ACh release, notwithstanding the fact that the ACh content of La3+-treated muscles was about the same as that of controls. 3. Hypertonic NaCl or raised KCl concentrations were used to increase m.e.p.c.s and this also increased ACh release; it was estimated that each quantum corresponded to the release of 12 000 molecules of ACh. 4. ACh release by nerve stimulation was greatly potentiated by 10 mM-tetraethylammonium chloride, and this enabled the ACh released by ten, and even single, stimuli to be detected; it was calculated from the ACh released and the quantal content that each quantum contained on the average 13 000 molecules. 5. ACh released by nerve stimulation at 0.2/s in the absence of tetraethylammonium was about half that expected on the basis of previous estimates of quantal content; it was increased about two-fold by alpha-bungarotoxin. 6. It is concluded that chemical and electrical stimulation of the nerve evoked quantal ACh release, without influencing non-quantal ACh leakage. The results are consistent with the view that ACh quanta are derived from synaptic vesicles. They also show that resting ACh release is not due to leakage of ACh ions along an electrochemical gradient in the membrane." @default.
• W2005681750 created "2016-06-24" @default.
• W2005681750 creator A5021801420 @default.
• W2005681750 creator A5035781296 @default.
• W2005681750 creator A5036865831 @default.
• W2005681750 date "1983-01-01" @default.
• W2005681750 modified "2023-10-14" @default.
• W2005681750 title "Electrophysiological and chemical determination of acetylcholine release at the frog neuromuscular junction." @default.
• W2005681750 cites W1419322135 @default.
• W2005681750 cites W1985222283 @default.
• W2005681750 cites W1987211927 @default.
• W2005681750 cites W2005587408 @default.
• W2005681750 cites W2008334722 @default.
• W2005681750 cites W2016507552 @default.
• W2005681750 cites W2033346446 @default.
• W2005681750 cites W2041093443 @default.
• W2005681750 cites W2050859687 @default.
• W2005681750 cites W2070366880 @default.
• W2005681750 cites W2072441257 @default.
• W2005681750 cites W2086742035 @default.
• W2005681750 cites W2090586645 @default.
• W2005681750 cites W2125302829 @default.
• W2005681750 cites W2131390454 @default.
• W2005681750 cites W2169072353 @default.
• W2005681750 cites W2408618676 @default.
• W2005681750 doi "https://doi.org/10.1113/jphysiol.1983.sp014492" @default.
• W2005681750 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1197312" @default.
• W2005681750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6602876" @default.
• W2005681750 hasPublicationYear "1983" @default.
• W2005681750 type Work @default.
• W2005681750 sameAs 2005681750 @default.
• W2005681750 citedByCount "49" @default.
• W2005681750 countsByYear W20056817502015 @default.
• W2005681750 countsByYear W20056817502018 @default.
• W2005681750 countsByYear W20056817502021 @default.
• W2005681750 crossrefType "journal-article" @default.
• W2005681750 hasAuthorship W2005681750A5021801420 @default.
• W2005681750 hasAuthorship W2005681750A5035781296 @default.
• W2005681750 hasAuthorship W2005681750A5036865831 @default.
• W2005681750 hasBestOaLocation W20056817501 @default.
• W2005681750 hasConcept C104317684 @default.
• W2005681750 hasConcept C12554922 @default.
• W2005681750 hasConcept C134018914 @default.
• W2005681750 hasConcept C169760540 @default.
• W2005681750 hasConcept C176704843 @default.
• W2005681750 hasConcept C178790620 @default.
• W2005681750 hasConcept C185592680 @default.
• W2005681750 hasConcept C24998067 @default.
• W2005681750 hasConcept C2775910092 @default.
• W2005681750 hasConcept C2777240379 @default.
• W2005681750 hasConcept C2778935311 @default.
• W2005681750 hasConcept C2779014961 @default.
• W2005681750 hasConcept C2779535977 @default.
• W2005681750 hasConcept C2781295685 @default.
• W2005681750 hasConcept C3018430268 @default.
• W2005681750 hasConcept C31896038 @default.
• W2005681750 hasConcept C517785266 @default.
• W2005681750 hasConcept C519063684 @default.
• W2005681750 hasConcept C55493867 @default.
• W2005681750 hasConcept C86803240 @default.
• W2005681750 hasConceptScore W2005681750C104317684 @default.
• W2005681750 hasConceptScore W2005681750C12554922 @default.
• W2005681750 hasConceptScore W2005681750C134018914 @default.
• W2005681750 hasConceptScore W2005681750C169760540 @default.
• W2005681750 hasConceptScore W2005681750C176704843 @default.
• W2005681750 hasConceptScore W2005681750C178790620 @default.
• W2005681750 hasConceptScore W2005681750C185592680 @default.
• W2005681750 hasConceptScore W2005681750C24998067 @default.
• W2005681750 hasConceptScore W2005681750C2775910092 @default.
• W2005681750 hasConceptScore W2005681750C2777240379 @default.
• W2005681750 hasConceptScore W2005681750C2778935311 @default.
• W2005681750 hasConceptScore W2005681750C2779014961 @default.
• W2005681750 hasConceptScore W2005681750C2779535977 @default.
• W2005681750 hasConceptScore W2005681750C2781295685 @default.
• W2005681750 hasConceptScore W2005681750C3018430268 @default.
• W2005681750 hasConceptScore W2005681750C31896038 @default.
• W2005681750 hasConceptScore W2005681750C517785266 @default.
• W2005681750 hasConceptScore W2005681750C519063684 @default.
• W2005681750 hasConceptScore W2005681750C55493867 @default.
• W2005681750 hasConceptScore W2005681750C86803240 @default.
• W2005681750 hasIssue "1" @default.
• W2005681750 hasLocation W20056817501 @default.
• W2005681750 hasLocation W20056817502 @default.
• W2005681750 hasLocation W20056817503 @default.
• W2005681750 hasOpenAccess W2005681750 @default.
• W2005681750 hasPrimaryLocation W20056817501 @default.
• W2005681750 hasRelatedWork W2002468465 @default.
• W2005681750 hasRelatedWork W2012290561 @default.
• W2005681750 hasRelatedWork W2012971558 @default.
• W2005681750 hasRelatedWork W2034453410 @default.
• W2005681750 hasRelatedWork W2062225722 @default.
• W2005681750 hasRelatedWork W2074743989 @default.
• W2005681750 hasRelatedWork W2088454678 @default.
• W2005681750 hasRelatedWork W2255483802 @default.
• W2005681750 hasRelatedWork W2322998735 @default.
• W2005681750 hasRelatedWork W2397859308 @default.
• W2005681750 hasVolume "334" @default.
• W2005681750 isParatext "false" @default.

• next