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- W2005684912 abstract "Rapid activation of platelets at sites of vascular injury is a critical event in thrombosis and hemostasis. Here, we review recent findings, which (a) identified CalDAG-GEFI (RasGRP2) at the nexus of the rapid Ca2+-dependent platelet activation, (b) demonstrated a complex synergy between signaling provided by CalDAG-GEFI, protein kinase C and the Gi-coupled receptor for ADP, P2Y12, and (c) suggested CalDAG-GEFI as a novel target for anti-platelet therapy." @default.
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- W2005684912 date "2010-01-01" @default.
- W2005684912 modified "2023-10-02" @default.
- W2005684912 title "CalDAG-GEFI and platelet activation" @default.
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- W2005684912 doi "https://doi.org/10.3109/09537101003639931" @default.
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