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- W2005697725 abstract "Orlistat, in the 60-mg over-the-counter dose, was recently approved by the FDA. This lipase inhibitor blocks absorption of ~ 25% of ingested fat and has ~ 85% of the efficacy of the 120-mg dose for weight loss. Over 16 weeks weight loss with diet and orlistat 60 mg averages ~ 5% of initial body weight. The 60-mg dose is better tolerated than the 120-mg dose and the gastrointestinal side effects are minimal when individuals consume < 30% of their energy from fat. In addition to facilitating modest weight loss, orlistat use decreases serum LDL-cholesterol values by ~ 10%. When taken three times daily before meals, orlistat 60 mg modifies lifestyle behavior, encourages lower fat-consumption and sets the stage for other healthy lifestyle changes." @default.
- W2005697725 created "2016-06-24" @default.
- W2005697725 creator A5030938899 @default.
- W2005697725 date "2007-08-01" @default.
- W2005697725 modified "2023-10-16" @default.
- W2005697725 title "Orlistat for the management of overweight individuals and obesity: a review of potential for the 60-mg, over-the-counter dosage" @default.
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- W2005697725 doi "https://doi.org/10.1517/14656566.8.11.1733" @default.
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