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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005707410> ?p ?o ?g. }

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• W2005707410 abstract "Carboxymethyl konjac glucomannan-chitosan (CKGM-CS) nanoparticles were spontaneously prepared under very mild conditions via polyelectrolyte complexation. Bovine serum albumin (BSA), as a model protein drug, was incorporated into the CKGM-CS nanoparticles. The physicochemical properties of the BSA-loaded nanoparticles were identified by Zetasizer 3000 and FTIR spectrophotometry. Their sizes were from 330 nm to 900 nm; zeta potentials were positive according to varies CKGM/CS ratios. The encapsulation efficiency was up 20%. The release behavior in vitro of BSA from the nanoparticles was also investigated. We could find that the BSA release from the CKGM-CS nanoparticles is much more influenced by the CS coating layer than by the CKGM inner structure. And the CKGM-CS matrices not only exhibited pH-responsive properties, but ionic strength-sensitive properties. These systems may present a potential for pulsatile protein drug delivery." @default.
• W2005707410 created "2016-06-24" @default.
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• W2005707410 date "2005-02-15" @default.
• W2005707410 modified "2023-10-14" @default.
• W2005707410 title "Novel polyelectrolyte carboxymethyl konjac glucomannan-chitosan nanoparticles for drug delivery. II. Release of albuminin vitro" @default.
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• W2005707410 doi "https://doi.org/10.1002/jbm.b.30156" @default.
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