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- W2005722151 endingPage "604" @default.
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- W2005722151 abstract "Numerous cellular proteins are post-translationally modified by the addition of the small modifier protein ubiquitin (Ub). The functional consequences of the type of ubiquitination vary, such that polyubiquitinated proteins are targeted for degradation by the proteasome, whereas monoubiquitination is implicated in other cellular functions, including endocytic trafficking and DNA repair. The monoubiquitination of trafficking cargoes, such as receptors and associated proteins, as well as of endocytic accessory Ub-binding proteins, raises the question of the precise function of monoubiquitin signals in the endocytic route. Recent biochemical and genetic evidence shows that multiple monoubiquitination of epidermal growth factor and platelet-derived growth factor receptors provides trafficking and sorting tags that ensure receptor endocytosis and degradation, whereas monoubiquitination of accessory proteins might play a role in regulating their function as Ub-receptors in the endosome." @default.
- W2005722151 created "2016-06-24" @default.
- W2005722151 creator A5034358950 @default.
- W2005722151 creator A5052435188 @default.
- W2005722151 creator A5082730369 @default.
- W2005722151 date "2003-11-01" @default.
- W2005722151 modified "2023-10-10" @default.
- W2005722151 title "Distinct monoubiquitin signals in receptor endocytosis" @default.
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- W2005722151 cites W1780544763 @default.
- W2005722151 cites W1832030339 @default.
- W2005722151 cites W1930762285 @default.
- W2005722151 cites W1938129101 @default.
- W2005722151 cites W1964261321 @default.
- W2005722151 cites W1965028987 @default.
- W2005722151 cites W1967343277 @default.
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- W2005722151 cites W1969309483 @default.
- W2005722151 cites W1969958451 @default.
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- W2005722151 cites W2034947351 @default.
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- W2005722151 doi "https://doi.org/10.1016/j.tibs.2003.09.005" @default.
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