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• W2005750416 abstract "The antiplatelet and antithrombotic effects of the oral combination treatment of ticlopidine and Ginkgo biloba extract (EGb 761) were studied in normal and thrombosis-induced rats. The ex vivo inhibitory effect on ADP-induced platelet aggregation of a small dose of ticlopidine (50 mg/kg/day) in combination with EGb 761 (40 mg/kg/day) was comparable to a larger dose of only ticlopidine (200 mg/kg/day). Bleeding time was also prolonged by 150%. Thrombus weight was also consistently decreased by a combination of ticlopidine and EGb 761 in an arterio-venous shunt model at two doses of ticlopidine (50 mg/kg) plus EGb 761 (20 mg/kg) and ticlopidine (50 mg/kg) plus EGb 761 (40 mg/kg). A combinatory treatment in acute thrombosis model in mice also showed a higher recovery than a single treatment." @default.
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• W2005750416 date "1998-07-01" @default.
• W2005750416 modified "2023-10-15" @default.
• W2005750416 title "Antiplatelet and Antithrombotic Effects of a Combination of Ticlopidine and Ginkgo biloba Ext (EGb 761)" @default.
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• W2005750416 doi "https://doi.org/10.1016/s0049-3848(98)00075-9" @default.
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