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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005751397> ?p ?o ?g. }

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• W2005751397 abstract "Several new (E) stilbenes were synthesized by a combination of a Wittig olefination followed by Mizoroki-Heck coupling reactions. These compounds were screened for antitumor activity in a panel of 8 human cancer cell lines by a colorimetric SRB assay. Several of these compounds exhibit strong cytotoxicity. The most active compound of this series showed an average IC(50) value of 0.03 μmol; it acts by apoptosis as shown by a dye-exclusion test, an extra acridine orange/ethidium bromide staining and DNA-laddering experiments." @default.
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• W2005751397 date "2012-08-01" @default.
• W2005751397 modified "2023-10-18" @default.
• W2005751397 title "Synthesis and biological evaluation of novel (E) stilbene-based antitumor agents" @default.
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• W2005751397 doi "https://doi.org/10.1016/j.ejmech.2012.06.015" @default.
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