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• W2005752880 abstract "Ethanol (20% w/v) given to female, C57BL/6 mice in their drinking water was previously shown to suppress natural killer (NK) cell cytolytic activity in a mixed splenocyte population. The present study was designed to examine the hypothesis that ethanol consumption independently results in inhibition of NK cell cytolytic activity. Mice were given 20% w/v ethanol in the drinking water for 2 weeks, and splenic NK cells were enriched up to 88% based on surface expression of NK1.l. Cytolytic activity of these freshly enriched NK cells from ethanol‐consuming mice against YAC‐1 lymphoma cells was inhibited an average of 41% relative to water‐drinking controls. Cytolytic activity of enriched NK cells from ethanol‐consuming mice was stimulated to levels equal to control water‐drinking mice after 16‐ to 18‐hr incubation in 1000 units/ml recombinant interleukin 2. These data indicate that in vitro cytolytic activity of NK cells from ethanol‐consuming mice is inhibited in the absence of other modulatory leukocytes." @default.
• W2005752880 created "2016-06-24" @default.
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• W2005752880 date "1994-06-01" @default.
• W2005752880 modified "2023-09-29" @default.
• W2005752880 title "Effects of Ethanol Consumption on Enriched Natural Killer Cells from C57BL/6 Mice" @default.
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• W2005752880 doi "https://doi.org/10.1111/j.1530-0277.1994.tb00921.x" @default.
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