FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005763882> ?p ?o ?g. }

• W2005763882 endingPage "431" @default.
• W2005763882 startingPage "423" @default.
• W2005763882 abstract "Lipopolysaccharide (LPS) produces a series of systemic and psychiatric changes called sickness behavior. In the present study, we characterized the LPS-induced decrease in novel object exploratory behaviors in BALB/c mice. As already reported, LPS (0.3–5 μg/mouse) induced dose- and time-dependent decreases in locomotor activity, food intake, social interaction, and exploration for novel objects, and an increase in immobility in the forced-swim test. Although the decrease in locomotor activity was ameliorated by 10 h postinjection, novel object exploratory behaviors remained decreased at 24 h and were observed even with the lowest dose of LPS. In an object exploration test, LPS shortened object exploration time but did not affect moving time or the frequency of object exploration. Although pre-exposure to the same object markedly decreased the duration of exploration and LPS did not change this reduction, LPS significantly impaired the exploration of a novel object that replaced the familiar one. LPS did not affect anxiety-like behaviors in open-field and elevated plus-maze tests. An LPS-induced increase in the number of c-Fos–immunoreactive cells was observed in several brain regions within 6 h of LPS administration, but the number of cells quickly returned to control levels, except in the central amygdala where the increase continued for 24 h. These results suggest that LPS most prominently affects object exploratory behaviors by impairing cognition and/or motivation including continuous attention and curiosity toward objects, and that this may be associated with activation of brain nuclei such as the central amygdala." @default.
• W2005763882 created "2016-06-24" @default.
• W2005763882 creator A5002904415 @default.
• W2005763882 creator A5027301316 @default.
• W2005763882 creator A5030452705 @default.
• W2005763882 creator A5046062768 @default.
• W2005763882 creator A5057015626 @default.
• W2005763882 creator A5058123444 @default.
• W2005763882 creator A5069871672 @default.
• W2005763882 creator A5083316968 @default.
• W2005763882 date "2012-03-01" @default.
• W2005763882 modified "2023-10-16" @default.
• W2005763882 title "Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala" @default.
• W2005763882 cites W1900191186 @default.
• W2005763882 cites W1963918819 @default.
• W2005763882 cites W1971051809 @default.
• W2005763882 cites W1973058915 @default.
• W2005763882 cites W1981695205 @default.
• W2005763882 cites W1982754908 @default.
• W2005763882 cites W1983245960 @default.
• W2005763882 cites W1996963098 @default.
• W2005763882 cites W2000405843 @default.
• W2005763882 cites W2005609308 @default.
• W2005763882 cites W2009828027 @default.
• W2005763882 cites W2011431839 @default.
• W2005763882 cites W2016411894 @default.
• W2005763882 cites W2017750602 @default.
• W2005763882 cites W2023637447 @default.
• W2005763882 cites W2023693401 @default.
• W2005763882 cites W2034876578 @default.
• W2005763882 cites W2043189848 @default.
• W2005763882 cites W2044982094 @default.
• W2005763882 cites W2045040998 @default.
• W2005763882 cites W2046199489 @default.
• W2005763882 cites W2046308436 @default.
• W2005763882 cites W2050037580 @default.
• W2005763882 cites W2061522343 @default.
• W2005763882 cites W2069855822 @default.
• W2005763882 cites W2073609618 @default.
• W2005763882 cites W2077535518 @default.
• W2005763882 cites W2088185033 @default.
• W2005763882 cites W2089299823 @default.
• W2005763882 cites W2098149780 @default.
• W2005763882 cites W2112699297 @default.
• W2005763882 cites W2126795224 @default.
• W2005763882 cites W2126944350 @default.
• W2005763882 cites W2127854743 @default.
• W2005763882 cites W2132931722 @default.
• W2005763882 cites W2134144722 @default.
• W2005763882 cites W2157874465 @default.
• W2005763882 doi "https://doi.org/10.1016/j.bbr.2011.12.027" @default.
• W2005763882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22209851" @default.
• W2005763882 hasPublicationYear "2012" @default.
• W2005763882 type Work @default.
• W2005763882 sameAs 2005763882 @default.
• W2005763882 citedByCount "88" @default.
• W2005763882 countsByYear W20057638822012 @default.
• W2005763882 countsByYear W20057638822013 @default.
• W2005763882 countsByYear W20057638822014 @default.
• W2005763882 countsByYear W20057638822015 @default.
• W2005763882 countsByYear W20057638822016 @default.
• W2005763882 countsByYear W20057638822017 @default.
• W2005763882 countsByYear W20057638822018 @default.
• W2005763882 countsByYear W20057638822019 @default.
• W2005763882 countsByYear W20057638822020 @default.
• W2005763882 countsByYear W20057638822021 @default.
• W2005763882 countsByYear W20057638822022 @default.
• W2005763882 countsByYear W20057638822023 @default.
• W2005763882 crossrefType "journal-article" @default.
• W2005763882 hasAuthorship W2005763882A5002904415 @default.
• W2005763882 hasAuthorship W2005763882A5027301316 @default.
• W2005763882 hasAuthorship W2005763882A5030452705 @default.
• W2005763882 hasAuthorship W2005763882A5046062768 @default.
• W2005763882 hasAuthorship W2005763882A5057015626 @default.
• W2005763882 hasAuthorship W2005763882A5058123444 @default.
• W2005763882 hasAuthorship W2005763882A5069871672 @default.
• W2005763882 hasAuthorship W2005763882A5083316968 @default.
• W2005763882 hasConcept C118552586 @default.
• W2005763882 hasConcept C126322002 @default.
• W2005763882 hasConcept C134018914 @default.
• W2005763882 hasConcept C15744967 @default.
• W2005763882 hasConcept C169760540 @default.
• W2005763882 hasConcept C169900460 @default.
• W2005763882 hasConcept C173586616 @default.
• W2005763882 hasConcept C2776035688 @default.
• W2005763882 hasConcept C2778754761 @default.
• W2005763882 hasConcept C2779085643 @default.
• W2005763882 hasConcept C2779144063 @default.
• W2005763882 hasConcept C33435437 @default.
• W2005763882 hasConcept C46312422 @default.
• W2005763882 hasConcept C558461103 @default.
• W2005763882 hasConcept C71924100 @default.
• W2005763882 hasConceptScore W2005763882C118552586 @default.
• W2005763882 hasConceptScore W2005763882C126322002 @default.
• W2005763882 hasConceptScore W2005763882C134018914 @default.
• W2005763882 hasConceptScore W2005763882C15744967 @default.
• W2005763882 hasConceptScore W2005763882C169760540 @default.
• W2005763882 hasConceptScore W2005763882C169900460 @default.

• next