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- W2005778820 abstract "Heparin-induced thrombocytopenia (HIT) is a serious, prothrombotic, immune-mediated adverse reaction triggered by heparin therapy. When HIT is diagnosed or suspected, heparins should be discontinued and an alternative, fast-acting, parenteral, nonheparin anticoagulation such as argatroban should be initiated. The recommended initial dose of argatroban in HIT is 2 μg/kg/minute with following adjustment to the activated partial thromboplastin times (aPTTs). There are limited and inconsistent data about dosing of argatroban therapy in ICU patients with multiple organ dysfunction syndrome [1,2]." @default.
- W2005778820 created "2016-06-24" @default.
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- W2005778820 date "2009-01-01" @default.
- W2005778820 modified "2023-09-29" @default.
- W2005778820 title "Argatroban for heparin-induced thrombocytopenia therapy in ICU patients with sepsis or multiple organ dysfunction syndrome" @default.
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- W2005778820 doi "https://doi.org/10.1186/cc7606" @default.
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