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- W2005807785 abstract "At concentrations of 1–10 μg/ml, cytochalasin B caused disaggregation of the early Rana pipiens gastrula, with increasing rapidity at higher concentrations. The tissues of the gastrula responded differentially to the drug in that each required different lengths of time to disaggregate upon treatment with cytochalasin B. Moreover, extensive disaggregation of endoderm and mesoderm was necessary before dorsal lip expansion ceased and gastrulation was inhibited. Thus, cytochalasin B may not directly inhibit cell locomotion within the gastrula, but appears to inhibit gastrulation by virtue of its effect on cell separation. Cytochalasm B produced a significant reduction in the electrophoretic mobilities of disaggregated endoderm and chordamesoderm cells of the late gastrula. The reduction was greater with increasing lengths of exposure to the drug. Cytochalasin B did not significantly alter the electrophoretic mobility of ectoderm cells." @default.
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- W2005807785 title "Effects of cytochalasin B on the adhesion and electrophoretic mobility of amphibian gastrula cells" @default.
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- W2005807785 doi "https://doi.org/10.1016/0012-1606(73)90346-1" @default.
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