FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005855274> ?p ?o ?g. }

• W2005855274 endingPage "98" @default.
• W2005855274 startingPage "92" @default.
• W2005855274 abstract "Cobalt (Co) is an essential trace element well known as a constituent of vitamin B(12), but different compounds of Co are also described as highly toxic and/or radiotoxic for individuals or the environment. In nuclear power plants, (58)Co and (60)Co are radioactive isotopes of cobalt present as activation products of stable Co and Ni used in alloys. Skin exposure is a current occupational risk in the hard metal and nuclear industries. As biochemical and molecular cobalt-induced toxicological mechanisms are not fully identified, we investigated cobalt toxicity in a model human keratinocyte cell line, HaCaT. In this study, we propose a model to determine the in vitro chemical impact on cell viability of a soluble form of cobalt (CoCl(2)) with or without gamma-ray doses to mimic contamination by (60)Co, to elucidate the mechanisms of cobalt intracellular chemical and radiological toxicity. Intracellular cobalt concentration was determined after HaCaT cell contamination and chemical toxicity was evaluated in terms of cellular viability and clonogenic survival. We investigated damage to DNA in HaCaT cells by combined treatment with chemical cobalt and a moderate gamma-ray dose. Additive effects of cobalt and irradiation were demonstrated. The underlying mechanism of cobalt toxicity is not clearly established, but our results seem to indicate that the toxicity of Co(II) and of irradiation arises from production of reactive oxygen species." @default.
• W2005855274 created "2016-06-24" @default.
• W2005855274 creator A5009895673 @default.
• W2005855274 creator A5019837574 @default.
• W2005855274 creator A5037462757 @default.
• W2005855274 creator A5078138458 @default.
• W2005855274 creator A5083609031 @default.
• W2005855274 creator A5086778028 @default.
• W2005855274 date "2010-02-01" @default.
• W2005855274 modified "2023-09-30" @default.
• W2005855274 title "Cobalt toxicity: Chemical and radiological combined effects on HaCaT keratinocyte cell line" @default.
• W2005855274 cites W1553763991 @default.
• W2005855274 cites W1914825094 @default.
• W2005855274 cites W1917341586 @default.
• W2005855274 cites W1971823313 @default.
• W2005855274 cites W1979854943 @default.
• W2005855274 cites W1985053841 @default.
• W2005855274 cites W1986399871 @default.
• W2005855274 cites W1986796571 @default.
• W2005855274 cites W1992881084 @default.
• W2005855274 cites W2001367811 @default.
• W2005855274 cites W2004898039 @default.
• W2005855274 cites W2006960282 @default.
• W2005855274 cites W2008040742 @default.
• W2005855274 cites W2010207397 @default.
• W2005855274 cites W2010818369 @default.
• W2005855274 cites W2018526118 @default.
• W2005855274 cites W2020366047 @default.
• W2005855274 cites W2032564815 @default.
• W2005855274 cites W2039540290 @default.
• W2005855274 cites W2040956844 @default.
• W2005855274 cites W2041462100 @default.
• W2005855274 cites W2051528952 @default.
• W2005855274 cites W2052402304 @default.
• W2005855274 cites W2059156332 @default.
• W2005855274 cites W2066241164 @default.
• W2005855274 cites W2068136858 @default.
• W2005855274 cites W2071331435 @default.
• W2005855274 cites W2074356401 @default.
• W2005855274 cites W2076531398 @default.
• W2005855274 cites W2086097093 @default.
• W2005855274 cites W2089701006 @default.
• W2005855274 cites W2092629964 @default.
• W2005855274 cites W2093825185 @default.
• W2005855274 cites W2093876470 @default.
• W2005855274 cites W2099381601 @default.
• W2005855274 cites W2100394941 @default.
• W2005855274 cites W2101952777 @default.
• W2005855274 cites W2112829136 @default.
• W2005855274 cites W2119046611 @default.
• W2005855274 cites W2137849505 @default.
• W2005855274 cites W2141528928 @default.
• W2005855274 cites W2143007353 @default.
• W2005855274 cites W2148271223 @default.
• W2005855274 cites W2150221429 @default.
• W2005855274 cites W2169464402 @default.
• W2005855274 cites W4252019951 @default.
• W2005855274 doi "https://doi.org/10.1016/j.tiv.2009.08.027" @default.
• W2005855274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19735721" @default.
• W2005855274 hasPublicationYear "2010" @default.
• W2005855274 type Work @default.
• W2005855274 sameAs 2005855274 @default.
• W2005855274 citedByCount "56" @default.
• W2005855274 countsByYear W20058552742012 @default.
• W2005855274 countsByYear W20058552742013 @default.
• W2005855274 countsByYear W20058552742014 @default.
• W2005855274 countsByYear W20058552742015 @default.
• W2005855274 countsByYear W20058552742016 @default.
• W2005855274 countsByYear W20058552742017 @default.
• W2005855274 countsByYear W20058552742018 @default.
• W2005855274 countsByYear W20058552742019 @default.
• W2005855274 countsByYear W20058552742020 @default.
• W2005855274 countsByYear W20058552742021 @default.
• W2005855274 countsByYear W20058552742022 @default.
• W2005855274 countsByYear W20058552742023 @default.
• W2005855274 crossrefType "journal-article" @default.
• W2005855274 hasAuthorship W2005855274A5009895673 @default.
• W2005855274 hasAuthorship W2005855274A5019837574 @default.
• W2005855274 hasAuthorship W2005855274A5037462757 @default.
• W2005855274 hasAuthorship W2005855274A5078138458 @default.
• W2005855274 hasAuthorship W2005855274A5083609031 @default.
• W2005855274 hasAuthorship W2005855274A5086778028 @default.
• W2005855274 hasConcept C118995209 @default.
• W2005855274 hasConcept C12554922 @default.
• W2005855274 hasConcept C13965031 @default.
• W2005855274 hasConcept C177322064 @default.
• W2005855274 hasConcept C178790620 @default.
• W2005855274 hasConcept C185592680 @default.
• W2005855274 hasConcept C202751555 @default.
• W2005855274 hasConcept C29730261 @default.
• W2005855274 hasConcept C48349386 @default.
• W2005855274 hasConcept C515602321 @default.
• W2005855274 hasConcept C55493867 @default.
• W2005855274 hasConcept C86803240 @default.
• W2005855274 hasConceptScore W2005855274C118995209 @default.
• W2005855274 hasConceptScore W2005855274C12554922 @default.
• W2005855274 hasConceptScore W2005855274C13965031 @default.
• W2005855274 hasConceptScore W2005855274C177322064 @default.

• next