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- W2005861330 abstract "In order to study the clinical and immunologic effects of a brief course of leukapheresis, 14 patients with clinically similar rheumatoid arthritis were segregated into 2 subgroups. Group A (7 patients) had subnormal lymphocyte tritiated thymidine incorporation to soluble antigens. After a brief course of leukapheresis, 6 of these 7 patients demonstrated substantial clinical improvement associated with significantly enhanced lymphocyte tritiated thymidine incorporation to soluble antigens. In contrast, none of the 7 patients in group B (normal immune functions) demonstrated similar changes in articular indices or lymphocyte proliferation. Thus, clinical improvement induced in a subset of rheumatoid arthritis patients appears to reflect modulation of function, and not simply immuno-suppression." @default.
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- W2005861330 date "1983-09-01" @default.
- W2005861330 modified "2023-10-16" @default.
- W2005861330 title "Leukapheresis in rheumatoid arthritis association of clinical improvement with reversal of anergy" @default.
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- W2005861330 doi "https://doi.org/10.1002/art.1780260904" @default.
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