FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005862479> ?p ?o ?g. }

• W2005862479 endingPage "456" @default.
• W2005862479 startingPage "446" @default.
• W2005862479 abstract "The congenital adrenal hyperplasias (CAH) are a group of inherited enzymatic defects of adrenal steroid biosynthesis. Deficiencies of each enzyme required in the steroid biosynthesis pathway are known, and these deficiencies are all inherited as autosomal recessive disorders. During pregnancy, maternal and fetal problems are confined to women who have 21-hydroxylase deficiency (P450c21 deficiency), 11-hydroxylase deficiency (P450c11 deficiency), and 3 beta-hydroxysteroid dehydrogenase deficiency (3 beta HSD deficiency), because other adrenal enzyme deficiencies are not compatible with fertility. The interposition of the placenta on the hypothalamic-pituitary-adrenal axis and other endocrine changes during pregnancy impact considerably on the clinical evaluation of the congenital adrenal hyperplasias. Successful management of CAH in pregnancy requires a firm knowledge of normal adrenal anatomic and endocrine changes that occur during gestation. Women with severe forms of CAH have decreased fertility rates because of oligo-ovulation, and successful conception requires a combination of good therapeutic compliance, careful endocrine monitoring, and often ovulation induction. From a fetal and neonatal standpoint, accurate prenatal diagnosis of 21-hydroxylase deficiency and 11-hydroxylase deficiency is now possible, which allows for prenatal treatment in an attempt to minimize clinical problems in the neonates. Prevention of masculinization of affected female fetuses by corticosteroid suppression has been attempted in both 21-hydroxylase deficiency and 11beta-hydroxylase deficiency CAH, with variable degrees of success. This review provides an overview of the congenital adrenal hyperplasias and their management during pregnancy." @default.
• W2005862479 created "2016-06-24" @default.
• W2005862479 creator A5027950157 @default.
• W2005862479 date "1998-12-01" @default.
• W2005862479 modified "2023-10-14" @default.
• W2005862479 title "Congenital adrenal hyperplasia in pregnancy" @default.
• W2005862479 cites W127526507 @default.
• W2005862479 cites W1523302597 @default.
• W2005862479 cites W1626316917 @default.
• W2005862479 cites W1960244799 @default.
• W2005862479 cites W1963680434 @default.
• W2005862479 cites W1967028270 @default.
• W2005862479 cites W1971390856 @default.
• W2005862479 cites W1971392736 @default.
• W2005862479 cites W1974218063 @default.
• W2005862479 cites W1977753635 @default.
• W2005862479 cites W1979219467 @default.
• W2005862479 cites W1991542972 @default.
• W2005862479 cites W1993887819 @default.
• W2005862479 cites W1994126656 @default.
• W2005862479 cites W1995623240 @default.
• W2005862479 cites W1998932075 @default.
• W2005862479 cites W2006046594 @default.
• W2005862479 cites W2008878130 @default.
• W2005862479 cites W2010208043 @default.
• W2005862479 cites W2010220947 @default.
• W2005862479 cites W2013266397 @default.
• W2005862479 cites W2015796188 @default.
• W2005862479 cites W2015813771 @default.
• W2005862479 cites W2021131551 @default.
• W2005862479 cites W2023665902 @default.
• W2005862479 cites W2026972853 @default.
• W2005862479 cites W2031910566 @default.
• W2005862479 cites W2040365834 @default.
• W2005862479 cites W2047107705 @default.
• W2005862479 cites W2049986152 @default.
• W2005862479 cites W2060619399 @default.
• W2005862479 cites W2063009554 @default.
• W2005862479 cites W2063753989 @default.
• W2005862479 cites W2067588604 @default.
• W2005862479 cites W2072266714 @default.
• W2005862479 cites W2074000225 @default.
• W2005862479 cites W2077415800 @default.
• W2005862479 cites W2091409195 @default.
• W2005862479 cites W2093713775 @default.
• W2005862479 cites W2105924023 @default.
• W2005862479 cites W2109353764 @default.
• W2005862479 cites W2110946696 @default.
• W2005862479 cites W2126373936 @default.
• W2005862479 cites W2159809219 @default.
• W2005862479 cites W2168852120 @default.
• W2005862479 cites W2178813467 @default.
• W2005862479 cites W2258330502 @default.
• W2005862479 cites W2320247473 @default.
• W2005862479 cites W2401899563 @default.
• W2005862479 cites W2405860439 @default.
• W2005862479 cites W4230915994 @default.
• W2005862479 cites W4235857157 @default.
• W2005862479 cites W4239040583 @default.
• W2005862479 cites W4239845649 @default.
• W2005862479 cites W4245980189 @default.
• W2005862479 cites W4246227908 @default.
• W2005862479 cites W4255132698 @default.
• W2005862479 cites W4321000944 @default.
• W2005862479 cites W1509101686 @default.
• W2005862479 doi "https://doi.org/10.1016/s0146-0005(98)80025-6" @default.
• W2005862479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9880115" @default.
• W2005862479 hasPublicationYear "1998" @default.
• W2005862479 type Work @default.
• W2005862479 sameAs 2005862479 @default.
• W2005862479 citedByCount "32" @default.
• W2005862479 countsByYear W20058624792012 @default.
• W2005862479 countsByYear W20058624792014 @default.
• W2005862479 countsByYear W20058624792016 @default.
• W2005862479 countsByYear W20058624792017 @default.
• W2005862479 countsByYear W20058624792020 @default.
• W2005862479 countsByYear W20058624792021 @default.
• W2005862479 countsByYear W20058624792023 @default.
• W2005862479 crossrefType "journal-article" @default.
• W2005862479 hasAuthorship W2005862479A5027950157 @default.
• W2005862479 hasConcept C126322002 @default.
• W2005862479 hasConcept C134018914 @default.
• W2005862479 hasConcept C155392382 @default.
• W2005862479 hasConcept C172680121 @default.
• W2005862479 hasConcept C2776899810 @default.
• W2005862479 hasConcept C2777767042 @default.
• W2005862479 hasConcept C2778709874 @default.
• W2005862479 hasConcept C2779234561 @default.
• W2005862479 hasConcept C2780321258 @default.
• W2005862479 hasConcept C2780902042 @default.
• W2005862479 hasConcept C3020590458 @default.
• W2005862479 hasConcept C46699223 @default.
• W2005862479 hasConcept C54355233 @default.
• W2005862479 hasConcept C71315377 @default.
• W2005862479 hasConcept C71924100 @default.
• W2005862479 hasConcept C86803240 @default.
• W2005862479 hasConceptScore W2005862479C126322002 @default.
• W2005862479 hasConceptScore W2005862479C134018914 @default.

• next