FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005881448> ?p ?o ?g. }

• W2005881448 endingPage "6443" @default.
• W2005881448 startingPage "6438" @default.
• W2005881448 abstract "In this paper the immobilization of small unilamellar DMPC/GM1 lipid vesicles containing a water-soluble bodipy dye is described. The binding of the complete alphabeta toxin expressed by Vibrio cholerae to the attached vesicles was measured using Surface Plasmon Resonance (SPR) and a value of the dissociation constant K d obtained. Further measurements showed that the interaction of both the alphabeta-toxin and the beta-subunit alone resulted in the permeation of the lipid membrane, with release of a fluorophore contained within the vesicle being measured by combined SPR and Surface Plasmon enhanced Fluorescence Spectroscopy (SPFS). The leakage of dye through the membrane, measured by following the change in fluorescence, was fitted to a simple diffusion model. Finally, SPFS measurements of the effect of europium(III) chloride (EuCl 3) showed that cholera toxin binding and subsequent membrane permeation could be blocked by 1 micromol dm (-3) europium chloride. In view of the low oral toxicity of europium chloride, we speculate on the potential pharmaceutical applications of this molecule in the treatment of cholera infection." @default.
• W2005881448 created "2016-06-24" @default.
• W2005881448 creator A5038511318 @default.
• W2005881448 creator A5068776297 @default.
• W2005881448 date "2008-04-16" @default.
• W2005881448 modified "2023-09-23" @default.
• W2005881448 title "Measurement of the Binding of Cholera Toxin to GM1 Gangliosides on Solid Supported Lipid Bilayer Vesicles and Inhibition by Europium (III) Chloride" @default.
• W2005881448 cites W1948066085 @default.
• W2005881448 cites W1966909518 @default.
• W2005881448 cites W1967584464 @default.
• W2005881448 cites W1970107908 @default.
• W2005881448 cites W1974858284 @default.
• W2005881448 cites W1981154770 @default.
• W2005881448 cites W1987978652 @default.
• W2005881448 cites W2004466150 @default.
• W2005881448 cites W2004835801 @default.
• W2005881448 cites W2006465296 @default.
• W2005881448 cites W2030490593 @default.
• W2005881448 cites W2037255630 @default.
• W2005881448 cites W2037874766 @default.
• W2005881448 cites W2052778643 @default.
• W2005881448 cites W2067287813 @default.
• W2005881448 cites W2083237454 @default.
• W2005881448 cites W2094264753 @default.
• W2005881448 cites W2094972308 @default.
• W2005881448 cites W2111679811 @default.
• W2005881448 cites W2125428954 @default.
• W2005881448 cites W2149863352 @default.
• W2005881448 cites W2158798662 @default.
• W2005881448 cites W2276363593 @default.
• W2005881448 cites W4211185542 @default.
• W2005881448 cites W4211207408 @default.
• W2005881448 cites W4230729241 @default.
• W2005881448 doi "https://doi.org/10.1021/ja710543x" @default.
• W2005881448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18412339" @default.
• W2005881448 hasPublicationYear "2008" @default.
• W2005881448 type Work @default.
• W2005881448 sameAs 2005881448 @default.
• W2005881448 citedByCount "24" @default.
• W2005881448 countsByYear W20058814482012 @default.
• W2005881448 countsByYear W20058814482013 @default.
• W2005881448 countsByYear W20058814482015 @default.
• W2005881448 countsByYear W20058814482016 @default.
• W2005881448 countsByYear W20058814482018 @default.
• W2005881448 countsByYear W20058814482021 @default.
• W2005881448 countsByYear W20058814482022 @default.
• W2005881448 countsByYear W20058814482023 @default.
• W2005881448 crossrefType "journal-article" @default.
• W2005881448 hasAuthorship W2005881448A5038511318 @default.
• W2005881448 hasAuthorship W2005881448A5068776297 @default.
• W2005881448 hasConcept C106847996 @default.
• W2005881448 hasConcept C121332964 @default.
• W2005881448 hasConcept C12554922 @default.
• W2005881448 hasConcept C127413603 @default.
• W2005881448 hasConcept C130316041 @default.
• W2005881448 hasConcept C145148216 @default.
• W2005881448 hasConcept C155672457 @default.
• W2005881448 hasConcept C178790620 @default.
• W2005881448 hasConcept C185154212 @default.
• W2005881448 hasConcept C185592680 @default.
• W2005881448 hasConcept C192157962 @default.
• W2005881448 hasConcept C2777006276 @default.
• W2005881448 hasConcept C2778617687 @default.
• W2005881448 hasConcept C2778695967 @default.
• W2005881448 hasConcept C2994048982 @default.
• W2005881448 hasConcept C39944091 @default.
• W2005881448 hasConcept C41625074 @default.
• W2005881448 hasConcept C42360764 @default.
• W2005881448 hasConcept C43617362 @default.
• W2005881448 hasConcept C502696234 @default.
• W2005881448 hasConcept C50670333 @default.
• W2005881448 hasConcept C55493867 @default.
• W2005881448 hasConcept C62520636 @default.
• W2005881448 hasConcept C86803240 @default.
• W2005881448 hasConcept C89423630 @default.
• W2005881448 hasConcept C91881484 @default.
• W2005881448 hasConceptScore W2005881448C106847996 @default.
• W2005881448 hasConceptScore W2005881448C121332964 @default.
• W2005881448 hasConceptScore W2005881448C12554922 @default.
• W2005881448 hasConceptScore W2005881448C127413603 @default.
• W2005881448 hasConceptScore W2005881448C130316041 @default.
• W2005881448 hasConceptScore W2005881448C145148216 @default.
• W2005881448 hasConceptScore W2005881448C155672457 @default.
• W2005881448 hasConceptScore W2005881448C178790620 @default.
• W2005881448 hasConceptScore W2005881448C185154212 @default.
• W2005881448 hasConceptScore W2005881448C185592680 @default.
• W2005881448 hasConceptScore W2005881448C192157962 @default.
• W2005881448 hasConceptScore W2005881448C2777006276 @default.
• W2005881448 hasConceptScore W2005881448C2778617687 @default.
• W2005881448 hasConceptScore W2005881448C2778695967 @default.
• W2005881448 hasConceptScore W2005881448C2994048982 @default.
• W2005881448 hasConceptScore W2005881448C39944091 @default.
• W2005881448 hasConceptScore W2005881448C41625074 @default.
• W2005881448 hasConceptScore W2005881448C42360764 @default.
• W2005881448 hasConceptScore W2005881448C43617362 @default.
• W2005881448 hasConceptScore W2005881448C502696234 @default.
• W2005881448 hasConceptScore W2005881448C50670333 @default.
• W2005881448 hasConceptScore W2005881448C55493867 @default.

• next