FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005909608> ?p ?o ?g. }

• W2005909608 endingPage "52" @default.
• W2005909608 startingPage "45" @default.
• W2005909608 abstract "Estrogen receptors (ER) of the MtTF4 tumor whose growth is inhibited by estradiol (E2) were analyzed and compared to those of tissues whose growth is stimulated by E2 (uterus and pituitary gland). Cytosol prepared in buffer containing protease inhibitors was incubated with [3H]tamoxifen aziridine ([3H]TAZ) in the presence or absence of non-radioactive competitor. The labeled proteins were precipitated, separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis in denaturing conditions and detected by fluorography. Two classes of ER were identified. The first class is of high molecular weight (Mr = 65,000-64,000). In normal tissues, it is indeed frequently made up of two subtypes as revealed by the presence of a doublet on autoradiograms. In the MtTF4 tumor these subtypes were only rarely suspected and never they were as marked and distinct as in normal tissues. The second class, of low molecular weight (Mr ! 54,000-52,000), is also frequently made up of two subtypes in the uterus and the proportion of this class is higher in the uterus of mature than of immature rats. The MtTF4 tumor contains this class of ER but, due to the presence of non-specifically labeled proteins in this region, its relative amount cannot be estimated and the doublet was exceptionally revealed. In the pituitary gland, this small receptor has not been found.(i) On the basis of molecular weight analyses, estrogen receptors are heterogeneous, (ii) the ER pattern depends on the type of tissue and the sexual maturity of rats but all the tissues examined contained at least one type of the classic high molecular weight receptor, and (iii) no evident correlation was found between the ER pattern and the positive or negative response to estradiol." @default.
• W2005909608 created "2016-06-24" @default.
• W2005909608 creator A5014983924 @default.
• W2005909608 creator A5020586053 @default.
• W2005909608 creator A5021062334 @default.
• W2005909608 creator A5054542277 @default.
• W2005909608 creator A5064976704 @default.
• W2005909608 date "1989-01-01" @default.
• W2005909608 modified "2023-09-27" @default.
• W2005909608 title "Size heterogeneity of affinity labeled estrogen receptors in the MtTF4 tumor whose growth is inhibited by estradiol, in pituitary gland and uterus" @default.
• W2005909608 cites W1538933671 @default.
• W2005909608 cites W1585098875 @default.
• W2005909608 cites W1969910721 @default.
• W2005909608 cites W1979029637 @default.
• W2005909608 cites W1980697583 @default.
• W2005909608 cites W1981306061 @default.
• W2005909608 cites W1985860736 @default.
• W2005909608 cites W2001368666 @default.
• W2005909608 cites W2002805645 @default.
• W2005909608 cites W2005707484 @default.
• W2005909608 cites W2007169317 @default.
• W2005909608 cites W2028549678 @default.
• W2005909608 cites W2031749932 @default.
• W2005909608 cites W2038939638 @default.
• W2005909608 cites W2045844572 @default.
• W2005909608 cites W2052552509 @default.
• W2005909608 cites W2056313591 @default.
• W2005909608 cites W2056821709 @default.
• W2005909608 cites W2059462683 @default.
• W2005909608 cites W2065104718 @default.
• W2005909608 cites W2072108911 @default.
• W2005909608 cites W2079363548 @default.
• W2005909608 cites W2080179758 @default.
• W2005909608 cites W2088591863 @default.
• W2005909608 cites W2092049238 @default.
• W2005909608 cites W2092615191 @default.
• W2005909608 cites W2100837269 @default.
• W2005909608 cites W2130372414 @default.
• W2005909608 cites W2149308203 @default.
• W2005909608 cites W2315368724 @default.
• W2005909608 cites W59321173 @default.
• W2005909608 doi "https://doi.org/10.1016/0022-4731(89)90012-5" @default.
• W2005909608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2913400" @default.
• W2005909608 hasPublicationYear "1989" @default.
• W2005909608 type Work @default.
• W2005909608 sameAs 2005909608 @default.
• W2005909608 citedByCount "5" @default.
• W2005909608 crossrefType "journal-article" @default.
• W2005909608 hasAuthorship W2005909608A5014983924 @default.
• W2005909608 hasAuthorship W2005909608A5020586053 @default.
• W2005909608 hasAuthorship W2005909608A5021062334 @default.
• W2005909608 hasAuthorship W2005909608A5054542277 @default.
• W2005909608 hasAuthorship W2005909608A5064976704 @default.
• W2005909608 hasConcept C101660505 @default.
• W2005909608 hasConcept C116084860 @default.
• W2005909608 hasConcept C121608353 @default.
• W2005909608 hasConcept C126322002 @default.
• W2005909608 hasConcept C134018914 @default.
• W2005909608 hasConcept C153911025 @default.
• W2005909608 hasConcept C170493617 @default.
• W2005909608 hasConcept C181199279 @default.
• W2005909608 hasConcept C185592680 @default.
• W2005909608 hasConcept C2777164284 @default.
• W2005909608 hasConcept C2777176818 @default.
• W2005909608 hasConcept C2777658017 @default.
• W2005909608 hasConcept C2779029589 @default.
• W2005909608 hasConcept C2779066055 @default.
• W2005909608 hasConcept C530470458 @default.
• W2005909608 hasConcept C55493867 @default.
• W2005909608 hasConcept C71315377 @default.
• W2005909608 hasConcept C71924100 @default.
• W2005909608 hasConcept C84606932 @default.
• W2005909608 hasConcept C86803240 @default.
• W2005909608 hasConcept C98539663 @default.
• W2005909608 hasConceptScore W2005909608C101660505 @default.
• W2005909608 hasConceptScore W2005909608C116084860 @default.
• W2005909608 hasConceptScore W2005909608C121608353 @default.
• W2005909608 hasConceptScore W2005909608C126322002 @default.
• W2005909608 hasConceptScore W2005909608C134018914 @default.
• W2005909608 hasConceptScore W2005909608C153911025 @default.
• W2005909608 hasConceptScore W2005909608C170493617 @default.
• W2005909608 hasConceptScore W2005909608C181199279 @default.
• W2005909608 hasConceptScore W2005909608C185592680 @default.
• W2005909608 hasConceptScore W2005909608C2777164284 @default.
• W2005909608 hasConceptScore W2005909608C2777176818 @default.
• W2005909608 hasConceptScore W2005909608C2777658017 @default.
• W2005909608 hasConceptScore W2005909608C2779029589 @default.
• W2005909608 hasConceptScore W2005909608C2779066055 @default.
• W2005909608 hasConceptScore W2005909608C530470458 @default.
• W2005909608 hasConceptScore W2005909608C55493867 @default.
• W2005909608 hasConceptScore W2005909608C71315377 @default.
• W2005909608 hasConceptScore W2005909608C71924100 @default.
• W2005909608 hasConceptScore W2005909608C84606932 @default.
• W2005909608 hasConceptScore W2005909608C86803240 @default.
• W2005909608 hasConceptScore W2005909608C98539663 @default.
• W2005909608 hasIssue "1" @default.
• W2005909608 hasLocation W20059096081 @default.
• W2005909608 hasLocation W20059096082 @default.

• next