FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005920747> ?p ?o ?g. }

• W2005920747 endingPage "369" @default.
• W2005920747 startingPage "362" @default.
• W2005920747 abstract "Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Many scientists think that the roles and regulation of G6PD in physiology and pathophysiology have been well established as the enzyme was first identified 80 years ago. And that G6PD has been extensively studied especially with respect to G6PD deficiency and its association with hemolysis, and with respect to the role G6PD plays in lipid metabolism. But there has been a growing understanding of the central importance of G6PD to cellular physiology as it is a major source of NADPH that is required by many essential cellular systems including the antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 system, and others. Indeed G6PD is essential for cell survival. It has also become evident that G6PD is highly regulated by many signals that affect transcription, post-translation, intracellular location, and interactions with other protein. Pathophysiologic roles for G6PD have also been identified in such disease processes as diabetes, aldosterone-induced endothelial dysfunction, cancer, and others. It is now clear that G6PD is under complex regulatory control and of central importance to many cellular processes. In this review the biochemistry, regulatory signals, physiologic roles, and pathophysiologic roles for G6PD that have been elucidated over the past 20 years are discussed. 2012 IUBMB IUBMB Life, 2012" @default.
• W2005920747 created "2016-06-24" @default.
• W2005920747 creator A5043024058 @default.
• W2005920747 date "2012-03-20" @default.
• W2005920747 modified "2023-10-17" @default.
• W2005920747 title "Glucose-6-phosphate dehydrogenase, NADPH, and cell survival" @default.
• W2005920747 cites W1499792579 @default.
• W2005920747 cites W1523040131 @default.
• W2005920747 cites W1551423798 @default.
• W2005920747 cites W1565410707 @default.
• W2005920747 cites W1611606593 @default.
• W2005920747 cites W1750981760 @default.
• W2005920747 cites W1874751834 @default.
• W2005920747 cites W1967575728 @default.
• W2005920747 cites W1967743526 @default.
• W2005920747 cites W1980106698 @default.
• W2005920747 cites W1981733779 @default.
• W2005920747 cites W1982219839 @default.
• W2005920747 cites W1982561342 @default.
• W2005920747 cites W1988500984 @default.
• W2005920747 cites W1992462947 @default.
• W2005920747 cites W1994149094 @default.
• W2005920747 cites W1998674312 @default.
• W2005920747 cites W2001853483 @default.
• W2005920747 cites W2004013719 @default.
• W2005920747 cites W2004878818 @default.
• W2005920747 cites W2008158334 @default.
• W2005920747 cites W2010151178 @default.
• W2005920747 cites W2018299587 @default.
• W2005920747 cites W2025512372 @default.
• W2005920747 cites W2025796657 @default.
• W2005920747 cites W2029115838 @default.
• W2005920747 cites W2030830391 @default.
• W2005920747 cites W2031526143 @default.
• W2005920747 cites W2045942033 @default.
• W2005920747 cites W2046100445 @default.
• W2005920747 cites W2047188149 @default.
• W2005920747 cites W2059318458 @default.
• W2005920747 cites W2065873565 @default.
• W2005920747 cites W2067459715 @default.
• W2005920747 cites W2076477755 @default.
• W2005920747 cites W2080053308 @default.
• W2005920747 cites W2080620268 @default.
• W2005920747 cites W2083027212 @default.
• W2005920747 cites W2084936552 @default.
• W2005920747 cites W2091916032 @default.
• W2005920747 cites W2093792755 @default.
• W2005920747 cites W2106400228 @default.
• W2005920747 cites W2108609254 @default.
• W2005920747 cites W2109865507 @default.
• W2005920747 cites W2111768081 @default.
• W2005920747 cites W2119239003 @default.
• W2005920747 cites W2121236281 @default.
• W2005920747 cites W2122238728 @default.
• W2005920747 cites W2127616500 @default.
• W2005920747 cites W2132554143 @default.
• W2005920747 cites W2169695895 @default.
• W2005920747 cites W2213385493 @default.
• W2005920747 cites W2218622247 @default.
• W2005920747 cites W93337911 @default.
• W2005920747 doi "https://doi.org/10.1002/iub.1017" @default.
• W2005920747 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3325335" @default.
• W2005920747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22431005" @default.
• W2005920747 hasPublicationYear "2012" @default.
• W2005920747 type Work @default.
• W2005920747 sameAs 2005920747 @default.
• W2005920747 citedByCount "486" @default.
• W2005920747 countsByYear W20059207472012 @default.
• W2005920747 countsByYear W20059207472013 @default.
• W2005920747 countsByYear W20059207472014 @default.
• W2005920747 countsByYear W20059207472015 @default.
• W2005920747 countsByYear W20059207472016 @default.
• W2005920747 countsByYear W20059207472017 @default.
• W2005920747 countsByYear W20059207472018 @default.
• W2005920747 countsByYear W20059207472019 @default.
• W2005920747 countsByYear W20059207472020 @default.
• W2005920747 countsByYear W20059207472021 @default.
• W2005920747 countsByYear W20059207472022 @default.
• W2005920747 countsByYear W20059207472023 @default.
• W2005920747 crossrefType "journal-article" @default.
• W2005920747 hasAuthorship W2005920747A5043024058 @default.
• W2005920747 hasBestOaLocation W20059207471 @default.
• W2005920747 hasConcept C181199279 @default.
• W2005920747 hasConcept C20251656 @default.
• W2005920747 hasConcept C2776317432 @default.
• W2005920747 hasConcept C2777989768 @default.
• W2005920747 hasConcept C2779719074 @default.
• W2005920747 hasConcept C2780196906 @default.
• W2005920747 hasConcept C3409486 @default.
• W2005920747 hasConcept C38485361 @default.
• W2005920747 hasConcept C55493867 @default.
• W2005920747 hasConcept C79879829 @default.
• W2005920747 hasConcept C86803240 @default.
• W2005920747 hasConcept C95444343 @default.
• W2005920747 hasConceptScore W2005920747C181199279 @default.
• W2005920747 hasConceptScore W2005920747C20251656 @default.
• W2005920747 hasConceptScore W2005920747C2776317432 @default.
• W2005920747 hasConceptScore W2005920747C2777989768 @default.

• next