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• W2005940417 abstract "PIM kinases have become targets of interest due to their association with biochemical mechanisms affecting survival, proliferation and cytokine production. 1,2,3-Triazolo[4,5-b]pyridines were identified as PIM inhibitors applying a scaffold hopping approach. Initial exploration around this scaffold and X-ray crystallographic data are hereby described." @default.
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• W2005940417 date "2012-02-01" @default.
• W2005940417 modified "2023-10-05" @default.
• W2005940417 title "Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors" @default.
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• W2005940417 doi "https://doi.org/10.1016/j.bmcl.2011.12.130" @default.
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