Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005965478> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2005965478 abstract "The authors had for aim to compare the therapeutic efficiency and tolerance of 2 NRTI+efavirenz (EFV) versus 2 NRTI+indinavir (IDV) in HIV infected adults in Abidjan.A retrospective and multicentric study was made on 327 HIV-1 naive patients, 142 in the EFV group and 185 in the IDV group followed in Abidjan from November 1998 to December 2003. The analysis concerned clinical advents (opportunistic infections) and immunovirological parameters (CD4, viral load). Patients received 2 NRTI such as AZT+3TC or D4T+3TC combined either with EFV or IDV. The principal judgement criterion was therapeutic failure. We assessed the percentage of patients with undetectable viral load and the frequency of grade 3-4 adverse effects after 24 months of follow-up.Clinical improvement of patients' state and regression of opportunistic infections were identical in the two groups. The average gain of CD4 was superior to 177 in EFV versus +219 in IDV (p=0.004). The percentage of patients with undetectable viral load was 66% for EFV versus 59% for IDV (p=0.04). The frequency of adverse effects was more elevated with EFV than IDV, 39% versus 23% (p=0.002) initially, but seemed to decrease later.HAART with EFV is at least as efficient as with IDV in terms of reduction of viral load and increased CD4 count and is an excellent low-cost first line treatment." @default.
- W2005965478 created "2016-06-24" @default.
- W2005965478 creator A5000580748 @default.
- W2005965478 creator A5008312486 @default.
- W2005965478 creator A5008812116 @default.
- W2005965478 creator A5017536653 @default.
- W2005965478 creator A5022418843 @default.
- W2005965478 creator A5027631262 @default.
- W2005965478 creator A5045905312 @default.
- W2005965478 creator A5066160065 @default.
- W2005965478 creator A5066551662 @default.
- W2005965478 creator A5069705000 @default.
- W2005965478 creator A5086454006 @default.
- W2005965478 date "2008-05-01" @default.
- W2005965478 modified "2023-10-17" @default.
- W2005965478 title "Efavirenz versus indinavir chez les patients naïfs infectés par le VIH-1 à Abidjan (Côte d’Ivoire)" @default.
- W2005965478 cites W1989041073 @default.
- W2005965478 cites W1992302794 @default.
- W2005965478 cites W1993443901 @default.
- W2005965478 cites W2004152021 @default.
- W2005965478 cites W2011608109 @default.
- W2005965478 cites W2016336666 @default.
- W2005965478 cites W2020705331 @default.
- W2005965478 cites W2033271256 @default.
- W2005965478 cites W2044252782 @default.
- W2005965478 cites W2044416560 @default.
- W2005965478 cites W2053712494 @default.
- W2005965478 cites W2162249113 @default.
- W2005965478 cites W2316853826 @default.
- W2005965478 cites W2321852728 @default.
- W2005965478 cites W2331247404 @default.
- W2005965478 doi "https://doi.org/10.1016/j.medmal.2008.02.004" @default.
- W2005965478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18395375" @default.
- W2005965478 hasPublicationYear "2008" @default.
- W2005965478 type Work @default.
- W2005965478 sameAs 2005965478 @default.
- W2005965478 citedByCount "5" @default.
- W2005965478 countsByYear W20059654782015 @default.
- W2005965478 countsByYear W20059654782016 @default.
- W2005965478 crossrefType "journal-article" @default.
- W2005965478 hasAuthorship W2005965478A5000580748 @default.
- W2005965478 hasAuthorship W2005965478A5008312486 @default.
- W2005965478 hasAuthorship W2005965478A5008812116 @default.
- W2005965478 hasAuthorship W2005965478A5017536653 @default.
- W2005965478 hasAuthorship W2005965478A5022418843 @default.
- W2005965478 hasAuthorship W2005965478A5027631262 @default.
- W2005965478 hasAuthorship W2005965478A5045905312 @default.
- W2005965478 hasAuthorship W2005965478A5066160065 @default.
- W2005965478 hasAuthorship W2005965478A5066551662 @default.
- W2005965478 hasAuthorship W2005965478A5069705000 @default.
- W2005965478 hasAuthorship W2005965478A5086454006 @default.
- W2005965478 hasConcept C142362112 @default.
- W2005965478 hasConcept C142462285 @default.
- W2005965478 hasConcept C15708023 @default.
- W2005965478 hasConcept C159047783 @default.
- W2005965478 hasConcept C2777210460 @default.
- W2005965478 hasConcept C2781432083 @default.
- W2005965478 hasConcept C29456083 @default.
- W2005965478 hasConcept C2993143319 @default.
- W2005965478 hasConcept C3013748606 @default.
- W2005965478 hasConcept C3017884845 @default.
- W2005965478 hasConcept C71924100 @default.
- W2005965478 hasConceptScore W2005965478C142362112 @default.
- W2005965478 hasConceptScore W2005965478C142462285 @default.
- W2005965478 hasConceptScore W2005965478C15708023 @default.
- W2005965478 hasConceptScore W2005965478C159047783 @default.
- W2005965478 hasConceptScore W2005965478C2777210460 @default.
- W2005965478 hasConceptScore W2005965478C2781432083 @default.
- W2005965478 hasConceptScore W2005965478C29456083 @default.
- W2005965478 hasConceptScore W2005965478C2993143319 @default.
- W2005965478 hasConceptScore W2005965478C3013748606 @default.
- W2005965478 hasConceptScore W2005965478C3017884845 @default.
- W2005965478 hasConceptScore W2005965478C71924100 @default.
- W2005965478 hasLocation W20059654781 @default.
- W2005965478 hasLocation W20059654782 @default.
- W2005965478 hasOpenAccess W2005965478 @default.
- W2005965478 hasPrimaryLocation W20059654781 @default.
- W2005965478 isParatext "false" @default.
- W2005965478 isRetracted "false" @default.
- W2005965478 magId "2005965478" @default.
- W2005965478 workType "article" @default.