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- W2005979259 abstract "Cimicidol-3-O-β-D-xyloside (1), one of the main components isolated from Cimicifugae rhizoma, is an active component with antiosteoporotic effect. The metabolism of 1 by rat intestinal bacteria was investigated, and two metabolites, 11β-hydroxycimigenol (2) and foetidinol (3), were isolated and characterized by spectroscopic means including two-dimensional NMR. Furthermore, the structures of six intermediates in the bacterial incubation were proposed on the basis of LC/MS analyses, and the possible metabolic pathway of the formation of 2, which passes through a unique sequence including hydrolysis, hydroxylation, and reduction, is discussed in detail." @default.
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- W2005979259 date "2008-02-01" @default.
- W2005979259 modified "2023-09-23" @default.
- W2005979259 title "An Unusual Metabolite of Cimicidol-3-O-β-D-xyloside fromCimicifugae rhizoma by Rat Intestinal Bacteria" @default.
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- W2005979259 doi "https://doi.org/10.1002/cbdv.200890026" @default.
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