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- W2005995934 abstract "The purine pharmacology of the platelet has focused on the identity of the so-called ‘P2T’ receptor, which was originally defined as having ADP as an agonist and ATP as a competitive antagonist, thereby distinguishing it from other P2 receptors, at which ATP is an agonist. Subsequently, it became axiomatic that ADP was a platelet agonist and ATP a platelet antagonist. However, because pharmacology is fundamentally a quantitative discipline, it is clearly important to have well-characterized and reliable tools for the investigation of receptor–ligand interactions and hence cellular function. The pharmacological classification of receptors is an explicit statement to the effect that this can be done meaningfully." @default.
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- W2005995934 date "2000-11-01" @default.
- W2005995934 modified "2023-09-23" @default.
- W2005995934 title "Platelets and P2X1: is ADP really an agonist?" @default.
- W2005995934 cites W1992168784 @default.
- W2005995934 doi "https://doi.org/10.1016/s0165-6147(00)01570-4" @default.
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