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- W2005995995 endingPage "309" @default.
- W2005995995 startingPage "295" @default.
- W2005995995 abstract "Melatonin is a hormone produced mainly in the pineal gland. Plasma levels exhibit a circadian variation with the highest concentration occurring at night. The human biologic effects of melatonin depend upon the time of day it is made available. One of these effects is the setting and resetting of circadian clocks (chronobiotic effect). Additionally, it may be a potent antioxidant and immunomodulator and has been shown to have anti-tumor, anticytokine, anti-insomnia, and anticachexia effects. Melatonin has also been shown to improve survival and performance status in patients with advanced cancer. Objective tumor response occurs with melatonin alone or when combined with interleukin-2 (IL-2). Further, melatonin reduces radiation- and chemotherapeutic-induced toxicity. Symptomatic and circadian disruption is linked to increased cancer risk. The chronobiotic capacity of melatonin to reset circadian clocks may provide a verifiable strategy to reduce cancer risk and enhance quality of life by diminishing cancer-induced circadian disruption." @default.
- W2005995995 created "2016-06-24" @default.
- W2005995995 creator A5033847671 @default.
- W2005995995 creator A5038175729 @default.
- W2005995995 creator A5071126837 @default.
- W2005995995 date "2005-07-01" @default.
- W2005995995 modified "2023-09-23" @default.
- W2005995995 title "The therapeutic application of melatonin in supportive care and palliative medicine" @default.
- W2005995995 cites W104717986 @default.
- W2005995995 cites W143323031 @default.
- W2005995995 cites W1634348887 @default.
- W2005995995 cites W1967189029 @default.
- W2005995995 cites W1968301922 @default.
- W2005995995 cites W1969657346 @default.
- W2005995995 cites W1970822477 @default.
- W2005995995 cites W1971445017 @default.
- W2005995995 cites W1974325142 @default.
- W2005995995 cites W1975025234 @default.
- W2005995995 cites W1976216594 @default.
- W2005995995 cites W1978461072 @default.
- W2005995995 cites W1983665527 @default.
- W2005995995 cites W1983875092 @default.
- W2005995995 cites W1985826300 @default.
- W2005995995 cites W1989405897 @default.
- W2005995995 cites W1989608949 @default.
- W2005995995 cites W1990373435 @default.
- W2005995995 cites W1995899406 @default.
- W2005995995 cites W1996148507 @default.
- W2005995995 cites W2002206403 @default.
- W2005995995 cites W2002720628 @default.
- W2005995995 cites W2002760141 @default.
- W2005995995 cites W2003874138 @default.
- W2005995995 cites W2004570094 @default.
- W2005995995 cites W2005016682 @default.
- W2005995995 cites W200941503 @default.
- W2005995995 cites W2010892354 @default.
- W2005995995 cites W2011485266 @default.
- W2005995995 cites W2011925229 @default.
- W2005995995 cites W2012272163 @default.
- W2005995995 cites W2012425496 @default.
- W2005995995 cites W2020360849 @default.
- W2005995995 cites W2020447311 @default.
- W2005995995 cites W2023777719 @default.
- W2005995995 cites W2024449200 @default.
- W2005995995 cites W2036538458 @default.
- W2005995995 cites W2038015423 @default.
- W2005995995 cites W2041887179 @default.
- W2005995995 cites W2045101379 @default.
- W2005995995 cites W2047816798 @default.
- W2005995995 cites W2048282173 @default.
- W2005995995 cites W2049998070 @default.
- W2005995995 cites W2051736701 @default.
- W2005995995 cites W2057088216 @default.
- W2005995995 cites W2057685116 @default.
- W2005995995 cites W2061708103 @default.
- W2005995995 cites W2062196582 @default.
- W2005995995 cites W2063678928 @default.
- W2005995995 cites W2066233701 @default.
- W2005995995 cites W2066472254 @default.
- W2005995995 cites W2068290690 @default.
- W2005995995 cites W2071946457 @default.
- W2005995995 cites W2074180870 @default.
- W2005995995 cites W2074267977 @default.
- W2005995995 cites W2077070870 @default.
- W2005995995 cites W2077485895 @default.
- W2005995995 cites W2080032179 @default.
- W2005995995 cites W2081985673 @default.
- W2005995995 cites W2084699449 @default.
- W2005995995 cites W2085104178 @default.
- W2005995995 cites W2085626908 @default.
- W2005995995 cites W2090517643 @default.
- W2005995995 cites W2100876687 @default.
- W2005995995 cites W2104233676 @default.
- W2005995995 cites W2104511643 @default.
- W2005995995 cites W2114797936 @default.
- W2005995995 cites W2115155158 @default.
- W2005995995 cites W2127228129 @default.
- W2005995995 cites W2127793420 @default.
- W2005995995 cites W2133750115 @default.
- W2005995995 cites W2139591183 @default.
- W2005995995 cites W2142622103 @default.
- W2005995995 cites W2152838010 @default.
- W2005995995 cites W2154269061 @default.
- W2005995995 cites W2155548807 @default.
- W2005995995 cites W2162277599 @default.
- W2005995995 cites W2167090973 @default.
- W2005995995 cites W2171732987 @default.
- W2005995995 cites W2172168775 @default.
- W2005995995 cites W21787028 @default.
- W2005995995 cites W2320413839 @default.
- W2005995995 cites W2341473203 @default.
- W2005995995 cites W2395631124 @default.
- W2005995995 cites W2409513133 @default.
- W2005995995 cites W330423145 @default.
- W2005995995 cites W4300477882 @default.
- W2005995995 cites W71653146 @default.
- W2005995995 cites W72256264 @default.
- W2005995995 doi "https://doi.org/10.1177/104990910502200412" @default.