FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005999997> ?p ?o ?g. }

• W2005999997 endingPage "1391" @default.
• W2005999997 startingPage "1387" @default.
• W2005999997 abstract "The DNA flanking the 5' sequence of the mouse 1alpha-hydroxylase gene has been cloned and sequenced. A TATA box has been located at -30 bp and aCCAAT box has been located at -79 bp. The gene's promoter activity has been demonstrated by using a luciferase reporter gene construct transfected into a modified pig kidney cell line, AOK-B50. Parathyroid hormone stimulates this promoter-directed synthesis of luciferase by 17-fold, whereas forskolin stimulates it by 3-fold. The action of parathyroid hormone is concentration-dependent. 1,25-Dihydroxyvitamin D3 does not suppress basal promoter activity and marginally suppresses parathyroid hormone-driven luciferase reporter activity. The promoter has three potential cAMP-responsive element sites, and two perfect and one imperfect AP-1 sites, while no DR-3 was detected. These results indicate that parathyroid hormone stimulates 25-hydroxyvitamin D3-1alpha-hydroxylase by acting on the promoter of the 1alpha-hydroxylase gene." @default.
• W2005999997 created "2016-06-24" @default.
• W2005999997 creator A5003873771 @default.
• W2005999997 creator A5015090135 @default.
• W2005999997 creator A5022136815 @default.
• W2005999997 creator A5033969667 @default.
• W2005999997 creator A5050843647 @default.
• W2005999997 creator A5054636847 @default.
• W2005999997 creator A5079374747 @default.
• W2005999997 creator A5089373241 @default.
• W2005999997 date "1998-02-17" @default.
• W2005999997 modified "2023-10-10" @default.
• W2005999997 title "Parathyroid hormone activation of the 25-hydroxyvitamin D ₃ -1α-hydroxylase gene promoter" @default.
• W2005999997 cites W1569934864 @default.
• W2005999997 cites W158470404 @default.
• W2005999997 cites W1965937833 @default.
• W2005999997 cites W1969600436 @default.
• W2005999997 cites W1986287429 @default.
• W2005999997 cites W1990205754 @default.
• W2005999997 cites W1999040357 @default.
• W2005999997 cites W2018381121 @default.
• W2005999997 cites W2023881622 @default.
• W2005999997 cites W2041876117 @default.
• W2005999997 cites W2058221812 @default.
• W2005999997 cites W2066059684 @default.
• W2005999997 cites W2092959403 @default.
• W2005999997 cites W2095271448 @default.
• W2005999997 cites W2115408020 @default.
• W2005999997 cites W2128635872 @default.
• W2005999997 cites W2137088362 @default.
• W2005999997 cites W2154823312 @default.
• W2005999997 cites W2161122200 @default.
• W2005999997 cites W2197704460 @default.
• W2005999997 cites W2227814214 @default.
• W2005999997 cites W2332207559 @default.
• W2005999997 cites W2335931427 @default.
• W2005999997 cites W2470517991 @default.
• W2005999997 cites W4231134694 @default.
• W2005999997 cites W4293247451 @default.
• W2005999997 cites W4377079766 @default.
• W2005999997 cites W53423959 @default.
• W2005999997 cites W2000461499 @default.
• W2005999997 doi "https://doi.org/10.1073/pnas.95.4.1387" @default.
• W2005999997 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/19012" @default.
• W2005999997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9465024" @default.
• W2005999997 hasPublicationYear "1998" @default.
• W2005999997 type Work @default.
• W2005999997 sameAs 2005999997 @default.
• W2005999997 citedByCount "232" @default.
• W2005999997 countsByYear W20059999972012 @default.
• W2005999997 countsByYear W20059999972013 @default.
• W2005999997 countsByYear W20059999972014 @default.
• W2005999997 countsByYear W20059999972015 @default.
• W2005999997 countsByYear W20059999972016 @default.
• W2005999997 countsByYear W20059999972017 @default.
• W2005999997 countsByYear W20059999972018 @default.
• W2005999997 countsByYear W20059999972019 @default.
• W2005999997 countsByYear W20059999972020 @default.
• W2005999997 countsByYear W20059999972021 @default.
• W2005999997 countsByYear W20059999972022 @default.
• W2005999997 countsByYear W20059999972023 @default.
• W2005999997 crossrefType "journal-article" @default.
• W2005999997 hasAuthorship W2005999997A5003873771 @default.
• W2005999997 hasAuthorship W2005999997A5015090135 @default.
• W2005999997 hasAuthorship W2005999997A5022136815 @default.
• W2005999997 hasAuthorship W2005999997A5033969667 @default.
• W2005999997 hasAuthorship W2005999997A5050843647 @default.
• W2005999997 hasAuthorship W2005999997A5054636847 @default.
• W2005999997 hasAuthorship W2005999997A5079374747 @default.
• W2005999997 hasAuthorship W2005999997A5089373241 @default.
• W2005999997 hasBestOaLocation W20059999971 @default.
• W2005999997 hasConcept C101762097 @default.
• W2005999997 hasConcept C104317684 @default.
• W2005999997 hasConcept C111335760 @default.
• W2005999997 hasConcept C126322002 @default.
• W2005999997 hasConcept C150194340 @default.
• W2005999997 hasConcept C153911025 @default.
• W2005999997 hasConcept C161733203 @default.
• W2005999997 hasConcept C185592680 @default.
• W2005999997 hasConcept C2781208988 @default.
• W2005999997 hasConcept C519063684 @default.
• W2005999997 hasConcept C54009773 @default.
• W2005999997 hasConcept C55493867 @default.
• W2005999997 hasConcept C65888428 @default.
• W2005999997 hasConcept C71924100 @default.
• W2005999997 hasConcept C86803240 @default.
• W2005999997 hasConceptScore W2005999997C101762097 @default.
• W2005999997 hasConceptScore W2005999997C104317684 @default.
• W2005999997 hasConceptScore W2005999997C111335760 @default.
• W2005999997 hasConceptScore W2005999997C126322002 @default.
• W2005999997 hasConceptScore W2005999997C150194340 @default.
• W2005999997 hasConceptScore W2005999997C153911025 @default.
• W2005999997 hasConceptScore W2005999997C161733203 @default.
• W2005999997 hasConceptScore W2005999997C185592680 @default.
• W2005999997 hasConceptScore W2005999997C2781208988 @default.
• W2005999997 hasConceptScore W2005999997C519063684 @default.
• W2005999997 hasConceptScore W2005999997C54009773 @default.
• W2005999997 hasConceptScore W2005999997C55493867 @default.

• next