Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006008908> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2006008908 endingPage "8" @default.
- W2006008908 startingPage "1" @default.
- W2006008908 abstract "Congenital lung lesions are highly complex with respect to pathogenesis and treatment. Large-scale analytical methods, like metabolomics, are now available to identify biomarkers of pathological phenotypes and to facilitate clinical management. Nuclear magnetic resonance (NMR) is a unique tool for translational research, as in vitro results can be potentially translated into in vivo magnetic resonance protocols. Three surgical biopsies, from congenital lung malformations, were analyzed in comparison with one control sample. Extracted hydrophilic metabolites were submitted to high resolution 1 H NMR spectroscopy and the relative concentration of 12 metabolites was estimated. In addition, two-dimensional NMR measurements were performed to complement the results obtained from standard monodimensional experiments. This is one of the first reports of in vitro metabolic profiling of congenital lung malformation. Preliminary data on a small set of samples highlights some altered metabolic ratios, dealing with the glucose conversion to lactate, to the relative concentration of phosphatidylcholine precursors, and to the presence of myoinositol. Interestingly some relations between congenital lung lesions and cancer metabolic alterations are found." @default.
- W2006008908 created "2016-06-24" @default.
- W2006008908 creator A5000942255 @default.
- W2006008908 creator A5002910733 @default.
- W2006008908 creator A5012665484 @default.
- W2006008908 creator A5047857110 @default.
- W2006008908 creator A5054092815 @default.
- W2006008908 creator A5056127616 @default.
- W2006008908 creator A5062836985 @default.
- W2006008908 date "2014-01-29" @default.
- W2006008908 modified "2023-10-16" @default.
- W2006008908 title "Altered Metabolic Profile in Congenital Lung Lesions Revealed by 1H Nuclear Magnetic Resonance Spectroscopy" @default.
- W2006008908 cites W1980014543 @default.
- W2006008908 cites W2020972813 @default.
- W2006008908 cites W2029228976 @default.
- W2006008908 cites W2050417061 @default.
- W2006008908 cites W2050866697 @default.
- W2006008908 cites W2051366884 @default.
- W2006008908 cites W2083166156 @default.
- W2006008908 cites W2083747066 @default.
- W2006008908 cites W2111115065 @default.
- W2006008908 cites W2120526364 @default.
- W2006008908 cites W2120610506 @default.
- W2006008908 cites W2126684945 @default.
- W2006008908 cites W2130784515 @default.
- W2006008908 cites W2140190085 @default.
- W2006008908 doi "https://doi.org/10.1155/2014/391836" @default.
- W2006008908 hasPublicationYear "2014" @default.
- W2006008908 type Work @default.
- W2006008908 sameAs 2006008908 @default.
- W2006008908 citedByCount "3" @default.
- W2006008908 countsByYear W20060089082014 @default.
- W2006008908 countsByYear W20060089082016 @default.
- W2006008908 countsByYear W20060089082019 @default.
- W2006008908 crossrefType "journal-article" @default.
- W2006008908 hasAuthorship W2006008908A5000942255 @default.
- W2006008908 hasAuthorship W2006008908A5002910733 @default.
- W2006008908 hasAuthorship W2006008908A5012665484 @default.
- W2006008908 hasAuthorship W2006008908A5047857110 @default.
- W2006008908 hasAuthorship W2006008908A5054092815 @default.
- W2006008908 hasAuthorship W2006008908A5056127616 @default.
- W2006008908 hasAuthorship W2006008908A5062836985 @default.
- W2006008908 hasBestOaLocation W20060089081 @default.
- W2006008908 hasConcept C121332964 @default.
- W2006008908 hasConcept C126322002 @default.
- W2006008908 hasConcept C126838900 @default.
- W2006008908 hasConcept C142724271 @default.
- W2006008908 hasConcept C143409427 @default.
- W2006008908 hasConcept C185592680 @default.
- W2006008908 hasConcept C207001950 @default.
- W2006008908 hasConcept C21565614 @default.
- W2006008908 hasConcept C2777714996 @default.
- W2006008908 hasConcept C2989005 @default.
- W2006008908 hasConcept C46141821 @default.
- W2006008908 hasConcept C54355233 @default.
- W2006008908 hasConcept C60644358 @default.
- W2006008908 hasConcept C66974803 @default.
- W2006008908 hasConcept C71924100 @default.
- W2006008908 hasConcept C86803240 @default.
- W2006008908 hasConceptScore W2006008908C121332964 @default.
- W2006008908 hasConceptScore W2006008908C126322002 @default.
- W2006008908 hasConceptScore W2006008908C126838900 @default.
- W2006008908 hasConceptScore W2006008908C142724271 @default.
- W2006008908 hasConceptScore W2006008908C143409427 @default.
- W2006008908 hasConceptScore W2006008908C185592680 @default.
- W2006008908 hasConceptScore W2006008908C207001950 @default.
- W2006008908 hasConceptScore W2006008908C21565614 @default.
- W2006008908 hasConceptScore W2006008908C2777714996 @default.
- W2006008908 hasConceptScore W2006008908C2989005 @default.
- W2006008908 hasConceptScore W2006008908C46141821 @default.
- W2006008908 hasConceptScore W2006008908C54355233 @default.
- W2006008908 hasConceptScore W2006008908C60644358 @default.
- W2006008908 hasConceptScore W2006008908C66974803 @default.
- W2006008908 hasConceptScore W2006008908C71924100 @default.
- W2006008908 hasConceptScore W2006008908C86803240 @default.
- W2006008908 hasFunder F4320321873 @default.
- W2006008908 hasLocation W20060089081 @default.
- W2006008908 hasLocation W20060089082 @default.
- W2006008908 hasOpenAccess W2006008908 @default.
- W2006008908 hasPrimaryLocation W20060089081 @default.
- W2006008908 hasRelatedWork W1980415379 @default.
- W2006008908 hasRelatedWork W2049680870 @default.
- W2006008908 hasRelatedWork W2067076695 @default.
- W2006008908 hasRelatedWork W2068448759 @default.
- W2006008908 hasRelatedWork W2073756112 @default.
- W2006008908 hasRelatedWork W2118672167 @default.
- W2006008908 hasRelatedWork W2408226591 @default.
- W2006008908 hasRelatedWork W2808610190 @default.
- W2006008908 hasRelatedWork W2945569588 @default.
- W2006008908 hasRelatedWork W4245529330 @default.
- W2006008908 hasVolume "2014" @default.
- W2006008908 isParatext "false" @default.
- W2006008908 isRetracted "false" @default.
- W2006008908 magId "2006008908" @default.
- W2006008908 workType "article" @default.