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- W2006036074 abstract "BACKGROUND CONTEXT: The transcription factor, nuclear factor kappaB (NFκB), is a heterodimeric DNA-binding protein that plays a critical role in the regulation of pro-inflammatory mediators, such as IL-1 and TNF, which might be involved in the pathology of degenerated disc disease. Recently, the transfection of decoy oligodeoxynucleotide (ODN) containing the NFκB cis element has been reported to be a potential therapeutic approach for inflammatory diseases. The application of naked NFκB decoy ODN for intervertebral disc (IVD) degeneration has not been examined." @default.
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- W2006036074 date "2005-07-01" @default.
- W2006036074 modified "2023-09-26" @default.
- W2006036074 title "P89. The intra-discal injection of naked NFκB decoy oligonucleotide is effective in restoring disc degeneration in the rabbit annular needle puncture model" @default.
- W2006036074 doi "https://doi.org/10.1016/j.spinee.2005.05.304" @default.
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