Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006039006> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2006039006 endingPage "113" @default.
- W2006039006 startingPage "107" @default.
- W2006039006 abstract "A relationship between analgesic abuse and urothelial renal pelvic tumors was first observed in 1965. Since then more than 100 cases of such tumors have been reported in abusers of phenacetin-containing drugs; most of these cases have been from Sweden. Many patients had a preexisting nephropathy with renal papillary necrosis. The total consumption of the drugs could be estimated to several kilograms, and the average period of consumption was 17 yr in the Göteborg study. The manifest development of the tumor often came a few years after the cessation of the drug abuse. The clinical picture and the pathologic findings are described and the five-year survival rate is given. Multiple tumors in the urinary tract were common. Carcinogenic factors are discussed. Phenacetin is an aromatic amide with N-hydroxylated metabolites, closely related to known carcinogenic amines like the naphthylamines which earlier caused occupational bladder cancer. Furthermore, the data on exposition (consumption) time and tumor induction time were very similar in occupational bladder cancer and in renal pelvic cancer related to analgesic abuse. Animal experiments of long-term phenacetin feeding have produced a high degree of papillary epithelial hyperplasia. Further investigations are under way." @default.
- W2006039006 created "2016-06-24" @default.
- W2006039006 creator A5033967641 @default.
- W2006039006 creator A5050975271 @default.
- W2006039006 creator A5061345878 @default.
- W2006039006 date "1978-01-01" @default.
- W2006039006 modified "2023-10-16" @default.
- W2006039006 title "Malignancies of the urinary tract and their relation to analgesic abuse" @default.
- W2006039006 cites W1602945598 @default.
- W2006039006 cites W1970201273 @default.
- W2006039006 cites W1976333869 @default.
- W2006039006 cites W2004810094 @default.
- W2006039006 cites W2008786817 @default.
- W2006039006 cites W2048609893 @default.
- W2006039006 cites W2057507828 @default.
- W2006039006 cites W2061055445 @default.
- W2006039006 cites W2077566576 @default.
- W2006039006 cites W2078123998 @default.
- W2006039006 cites W2162048362 @default.
- W2006039006 cites W2283438955 @default.
- W2006039006 cites W2324153537 @default.
- W2006039006 cites W2408803083 @default.
- W2006039006 cites W2408846885 @default.
- W2006039006 cites W2409132348 @default.
- W2006039006 cites W2412277710 @default.
- W2006039006 cites W2419140919 @default.
- W2006039006 cites W2434986555 @default.
- W2006039006 cites W4299436876 @default.
- W2006039006 doi "https://doi.org/10.1038/ki.1978.13" @default.
- W2006039006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/713263" @default.
- W2006039006 hasPublicationYear "1978" @default.
- W2006039006 type Work @default.
- W2006039006 sameAs 2006039006 @default.
- W2006039006 citedByCount "99" @default.
- W2006039006 countsByYear W20060390062012 @default.
- W2006039006 countsByYear W20060390062013 @default.
- W2006039006 countsByYear W20060390062015 @default.
- W2006039006 countsByYear W20060390062017 @default.
- W2006039006 countsByYear W20060390062018 @default.
- W2006039006 countsByYear W20060390062022 @default.
- W2006039006 crossrefType "journal-article" @default.
- W2006039006 hasAuthorship W2006039006A5033967641 @default.
- W2006039006 hasAuthorship W2006039006A5050975271 @default.
- W2006039006 hasAuthorship W2006039006A5061345878 @default.
- W2006039006 hasBestOaLocation W20060390061 @default.
- W2006039006 hasConcept C121608353 @default.
- W2006039006 hasConcept C126322002 @default.
- W2006039006 hasConcept C126894567 @default.
- W2006039006 hasConcept C142724271 @default.
- W2006039006 hasConcept C2775922563 @default.
- W2006039006 hasConcept C2780091579 @default.
- W2006039006 hasConcept C2780229479 @default.
- W2006039006 hasConcept C2780352672 @default.
- W2006039006 hasConcept C2780820201 @default.
- W2006039006 hasConcept C71924100 @default.
- W2006039006 hasConcept C77411442 @default.
- W2006039006 hasConcept C98274493 @default.
- W2006039006 hasConceptScore W2006039006C121608353 @default.
- W2006039006 hasConceptScore W2006039006C126322002 @default.
- W2006039006 hasConceptScore W2006039006C126894567 @default.
- W2006039006 hasConceptScore W2006039006C142724271 @default.
- W2006039006 hasConceptScore W2006039006C2775922563 @default.
- W2006039006 hasConceptScore W2006039006C2780091579 @default.
- W2006039006 hasConceptScore W2006039006C2780229479 @default.
- W2006039006 hasConceptScore W2006039006C2780352672 @default.
- W2006039006 hasConceptScore W2006039006C2780820201 @default.
- W2006039006 hasConceptScore W2006039006C71924100 @default.
- W2006039006 hasConceptScore W2006039006C77411442 @default.
- W2006039006 hasConceptScore W2006039006C98274493 @default.
- W2006039006 hasIssue "1" @default.
- W2006039006 hasLocation W20060390061 @default.
- W2006039006 hasLocation W20060390062 @default.
- W2006039006 hasOpenAccess W2006039006 @default.
- W2006039006 hasPrimaryLocation W20060390061 @default.
- W2006039006 hasRelatedWork W11876081 @default.
- W2006039006 hasRelatedWork W1503212981 @default.
- W2006039006 hasRelatedWork W2018561676 @default.
- W2006039006 hasRelatedWork W2031113654 @default.
- W2006039006 hasRelatedWork W2438219729 @default.
- W2006039006 hasRelatedWork W2976394404 @default.
- W2006039006 hasRelatedWork W4230843102 @default.
- W2006039006 hasRelatedWork W89690859 @default.
- W2006039006 hasRelatedWork W1703578142 @default.
- W2006039006 hasRelatedWork W2414880926 @default.
- W2006039006 hasVolume "13" @default.
- W2006039006 isParatext "false" @default.
- W2006039006 isRetracted "false" @default.
- W2006039006 magId "2006039006" @default.
- W2006039006 workType "article" @default.