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- W2006047898 abstract "Purpose: To describe the technique and outcomes of limbal stem cell–sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). Methods: In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patients had isolated KGB, 2 were affected with the Ehlers–Danlos syndrome, and the other subject had osteogenesis imperfecta. Epithelial healing, anatomical results (corneal thickness and keratometry), and visual outcomes were evaluated after this intervention. Results: Three of the 6 patients were male. Complete epithelial healing occurred in 7 eyes during 2 weeks. Refractory persistent epithelial defect and graft melting occurred in 1 eye. Corneal thickness increased and central keratometry decreased after the LSCS-LKP was performed in all the patients. The patients were followed up for at least 6 months. Visual acuity improved in all eyes except 1. Conclusions: LSCS-LKP is an effective procedure for preserving ocular integrity and for improving visual acuity in patients with advanced KGB. Early surgical intervention can be considered before the occurrence of vision-threatening traumatic corneal rupture." @default.
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- W2006047898 date "2014-01-01" @default.
- W2006047898 modified "2023-09-27" @default.
- W2006047898 title "Limbal Stem Cell–Sparing Lamellar Keratoplasty for the Management of Advanced Keratoglobus" @default.
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- W2006047898 doi "https://doi.org/10.1097/ico.0b013e3182a9b1ac" @default.
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