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- W2006058152 abstract "4-Phosphono-β-lactams are synthesized via a three-step sequence, including final formation of the C3-C4 bond through a phosphorus-stabilized carbanion. The chlorinated precursors can be synthesized via two different methods: a one-pot N-acylation of an aromatic imine followed by addition of a trialkyl phosphite or phosphonylation of a suitable imine followed by N-acylation in a separate reaction step. The former method was preferred because of the ease of the reaction and the good yields obtained." @default.
- W2006058152 created "2016-06-24" @default.
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- W2006058152 date "2006-05-16" @default.
- W2006058152 modified "2023-09-23" @default.
- W2006058152 title "One-Pot Synthesis of N-Chloroacetyl 1-Aminoalkyl Phosphonates — Precursors of 4-Phosphono-β-lactams." @default.
- W2006058152 doi "https://doi.org/10.1002/chin.200620179" @default.
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