Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006064981> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2006064981 endingPage "10" @default.
- W2006064981 startingPage "6" @default.
- W2006064981 abstract "Middle ear cholesteatoma is destructive to auditory ossicles and temporal bone, and treatment usually requires surgical removal of all epithelial content. Epidermal growth factor (EGF) can stimulate the growth and differentiation of a variety of mammalian cells, including epithelial cells. Our study used the avidin-biotin complex technique to evaluate the expression of EGF in 40 cases of middle ear cholesteatoma (active cholesteatoma, 31 cases; inactive cholesteatoma, 9 cases) and 34 normal postauricular skin samples. In middle ear cholesteatoma, EGF was expressed in squamous epithelium in 21 cases (53%), fibroblasts in two cases (5%), and cholesteatoma endothelium in two cases (5%). In normal postauricular skin, EGF was expressed in squamous epithelium in 14 samples (41%), fibroblasts in one sample (3%), and endothelium in none. No statistical difference in EGF expression was found between cholesteatoma and normal postauricular skin samples. These results show that the distribution of EGF in middle ear cholesteatoma is not deranged and that the progression of cholesteatoma might be induced by the release of factors from the cholesteatoma matrix via autocrine stimulation, or by inflammatory cells of the subepithelial tissue through paracrine stimulation, or in both of these ways." @default.
- W2006064981 created "2016-06-24" @default.
- W2006064981 creator A5007376349 @default.
- W2006064981 creator A5015650046 @default.
- W2006064981 creator A5016638410 @default.
- W2006064981 creator A5019891754 @default.
- W2006064981 creator A5034870623 @default.
- W2006064981 creator A5045282606 @default.
- W2006064981 creator A5052211605 @default.
- W2006064981 creator A5066902397 @default.
- W2006064981 creator A5070086522 @default.
- W2006064981 date "2004-01-01" @default.
- W2006064981 modified "2023-09-26" @default.
- W2006064981 title "Epidermal Growth Factor Expression in Middle Ear Cholesteatoma" @default.
- W2006064981 cites W1966883150 @default.
- W2006064981 cites W1981753133 @default.
- W2006064981 cites W1993181695 @default.
- W2006064981 cites W1995751918 @default.
- W2006064981 cites W2000490940 @default.
- W2006064981 cites W2000896060 @default.
- W2006064981 cites W2001777680 @default.
- W2006064981 cites W2015638950 @default.
- W2006064981 cites W2021647631 @default.
- W2006064981 cites W2031480638 @default.
- W2006064981 cites W2035917353 @default.
- W2006064981 cites W2056463810 @default.
- W2006064981 cites W2063622081 @default.
- W2006064981 cites W2067880148 @default.
- W2006064981 cites W2134466000 @default.
- W2006064981 cites W4254488860 @default.
- W2006064981 doi "https://doi.org/10.1016/s1607-551x(09)70077-4" @default.
- W2006064981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15481560" @default.
- W2006064981 hasPublicationYear "2004" @default.
- W2006064981 type Work @default.
- W2006064981 sameAs 2006064981 @default.
- W2006064981 citedByCount "4" @default.
- W2006064981 countsByYear W20060649812013 @default.
- W2006064981 countsByYear W20060649812020 @default.
- W2006064981 crossrefType "journal-article" @default.
- W2006064981 hasAuthorship W2006064981A5007376349 @default.
- W2006064981 hasAuthorship W2006064981A5015650046 @default.
- W2006064981 hasAuthorship W2006064981A5016638410 @default.
- W2006064981 hasAuthorship W2006064981A5019891754 @default.
- W2006064981 hasAuthorship W2006064981A5034870623 @default.
- W2006064981 hasAuthorship W2006064981A5045282606 @default.
- W2006064981 hasAuthorship W2006064981A5052211605 @default.
- W2006064981 hasAuthorship W2006064981A5066902397 @default.
- W2006064981 hasAuthorship W2006064981A5070086522 @default.
- W2006064981 hasBestOaLocation W20060649811 @default.
- W2006064981 hasConcept C105702510 @default.
- W2006064981 hasConcept C126322002 @default.
- W2006064981 hasConcept C128240485 @default.
- W2006064981 hasConcept C141071460 @default.
- W2006064981 hasConcept C142724271 @default.
- W2006064981 hasConcept C170493617 @default.
- W2006064981 hasConcept C2776362946 @default.
- W2006064981 hasConcept C2777846895 @default.
- W2006064981 hasConcept C2780725665 @default.
- W2006064981 hasConcept C529295009 @default.
- W2006064981 hasConcept C71924100 @default.
- W2006064981 hasConcept C7876069 @default.
- W2006064981 hasConceptScore W2006064981C105702510 @default.
- W2006064981 hasConceptScore W2006064981C126322002 @default.
- W2006064981 hasConceptScore W2006064981C128240485 @default.
- W2006064981 hasConceptScore W2006064981C141071460 @default.
- W2006064981 hasConceptScore W2006064981C142724271 @default.
- W2006064981 hasConceptScore W2006064981C170493617 @default.
- W2006064981 hasConceptScore W2006064981C2776362946 @default.
- W2006064981 hasConceptScore W2006064981C2777846895 @default.
- W2006064981 hasConceptScore W2006064981C2780725665 @default.
- W2006064981 hasConceptScore W2006064981C529295009 @default.
- W2006064981 hasConceptScore W2006064981C71924100 @default.
- W2006064981 hasConceptScore W2006064981C7876069 @default.
- W2006064981 hasIssue "1" @default.
- W2006064981 hasLocation W20060649811 @default.
- W2006064981 hasLocation W20060649812 @default.
- W2006064981 hasOpenAccess W2006064981 @default.
- W2006064981 hasPrimaryLocation W20060649811 @default.
- W2006064981 hasRelatedWork W119761064 @default.
- W2006064981 hasRelatedWork W1699289173 @default.
- W2006064981 hasRelatedWork W1981753133 @default.
- W2006064981 hasRelatedWork W2006064981 @default.
- W2006064981 hasRelatedWork W2038472828 @default.
- W2006064981 hasRelatedWork W2083275631 @default.
- W2006064981 hasRelatedWork W2090421149 @default.
- W2006064981 hasRelatedWork W2124494252 @default.
- W2006064981 hasRelatedWork W2144000177 @default.
- W2006064981 hasRelatedWork W2349371548 @default.
- W2006064981 hasVolume "20" @default.
- W2006064981 isParatext "false" @default.
- W2006064981 isRetracted "false" @default.
- W2006064981 magId "2006064981" @default.
- W2006064981 workType "article" @default.