Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006083918> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2006083918 endingPage "456" @default.
- W2006083918 startingPage "442" @default.
- W2006083918 abstract "The sex-linked temperature-sensitive mutation, shibirets1, which causes, at the restrictive temperature, adult paralysis and pleiotropic morphological defects in embryonic, larval, and pupal development, has been shown to exhibit temperature-sensitive inhibition of differentiation in embryonic cultures in vitro. When shi cultures were incubated at 30°C for 24 hr, both muscle and neuron differentiation were inhibited more than 90% compared to control shi cultures incubated at 20°C. Heat shift experiments showed that the temperature-sensitive periods for neuron and muscle differentiation occurred at 11 to 18 and 14 to 16 hr, respectively, where zero time was the initiation of gastrulation in donor embryos. Short heat pulses (4 and 8 hr) which extended into the temperature-sensitive period resulted in moderate inhibition of differentiation; greater inhibition occurred as the duration of the pulses increased. In contrast, heating wild-type Oregon-R cultures at 30°C for 24 hr did not inhibit muscle cell differentiation and inhibited neuron differentiation relatively little. The temperature-sensitive period in shibire for muscle differentiation occurred well after myoblast division, during the period of myocyte elongation, aggregation, and fusion, whereas that for neuron differentiation took place during a period of enzyme synthesis (acetylcholinesterase and choline acetyltransferase) and axon elongation. Thus, the shi temperature-sensitive gene product affects at least two different cell types, in vitro, at different times during differentiation." @default.
- W2006083918 created "2016-06-24" @default.
- W2006083918 creator A5002071192 @default.
- W2006083918 creator A5069757778 @default.
- W2006083918 creator A5090911936 @default.
- W2006083918 date "1978-10-01" @default.
- W2006083918 modified "2023-09-25" @default.
- W2006083918 title "Temperature sensitivity of muscle and neuron differentiation in embryonic cell cultures from the Drosophila mutant, shibirets1" @default.
- W2006083918 cites W1557507829 @default.
- W2006083918 cites W1973010127 @default.
- W2006083918 cites W1983701110 @default.
- W2006083918 cites W1993898140 @default.
- W2006083918 cites W1994405664 @default.
- W2006083918 cites W2003259623 @default.
- W2006083918 cites W2020892162 @default.
- W2006083918 cites W2038230131 @default.
- W2006083918 cites W2039438302 @default.
- W2006083918 cites W2059602440 @default.
- W2006083918 cites W2079102093 @default.
- W2006083918 cites W2084817067 @default.
- W2006083918 cites W2092909093 @default.
- W2006083918 cites W2143120553 @default.
- W2006083918 cites W2998073875 @default.
- W2006083918 cites W1971516489 @default.
- W2006083918 doi "https://doi.org/10.1016/0012-1606(78)90250-6" @default.
- W2006083918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/100358" @default.
- W2006083918 hasPublicationYear "1978" @default.
- W2006083918 type Work @default.
- W2006083918 sameAs 2006083918 @default.
- W2006083918 citedByCount "12" @default.
- W2006083918 crossrefType "journal-article" @default.
- W2006083918 hasAuthorship W2006083918A5002071192 @default.
- W2006083918 hasAuthorship W2006083918A5069757778 @default.
- W2006083918 hasAuthorship W2006083918A5090911936 @default.
- W2006083918 hasConcept C104317684 @default.
- W2006083918 hasConcept C127413603 @default.
- W2006083918 hasConcept C143065580 @default.
- W2006083918 hasConcept C145103041 @default.
- W2006083918 hasConcept C169760540 @default.
- W2006083918 hasConcept C21200559 @default.
- W2006083918 hasConcept C24326235 @default.
- W2006083918 hasConcept C2776041557 @default.
- W2006083918 hasConcept C2778794669 @default.
- W2006083918 hasConcept C54355233 @default.
- W2006083918 hasConcept C86803240 @default.
- W2006083918 hasConcept C95444343 @default.
- W2006083918 hasConceptScore W2006083918C104317684 @default.
- W2006083918 hasConceptScore W2006083918C127413603 @default.
- W2006083918 hasConceptScore W2006083918C143065580 @default.
- W2006083918 hasConceptScore W2006083918C145103041 @default.
- W2006083918 hasConceptScore W2006083918C169760540 @default.
- W2006083918 hasConceptScore W2006083918C21200559 @default.
- W2006083918 hasConceptScore W2006083918C24326235 @default.
- W2006083918 hasConceptScore W2006083918C2776041557 @default.
- W2006083918 hasConceptScore W2006083918C2778794669 @default.
- W2006083918 hasConceptScore W2006083918C54355233 @default.
- W2006083918 hasConceptScore W2006083918C86803240 @default.
- W2006083918 hasConceptScore W2006083918C95444343 @default.
- W2006083918 hasIssue "2" @default.
- W2006083918 hasLocation W20060839181 @default.
- W2006083918 hasLocation W20060839182 @default.
- W2006083918 hasOpenAccess W2006083918 @default.
- W2006083918 hasPrimaryLocation W20060839181 @default.
- W2006083918 hasRelatedWork W1969421403 @default.
- W2006083918 hasRelatedWork W2006083918 @default.
- W2006083918 hasRelatedWork W2018569889 @default.
- W2006083918 hasRelatedWork W2156674132 @default.
- W2006083918 hasRelatedWork W2215223126 @default.
- W2006083918 hasRelatedWork W2790748761 @default.
- W2006083918 hasRelatedWork W2998957234 @default.
- W2006083918 hasRelatedWork W3096893558 @default.
- W2006083918 hasRelatedWork W4233680173 @default.
- W2006083918 hasRelatedWork W4242552279 @default.
- W2006083918 hasVolume "66" @default.
- W2006083918 isParatext "false" @default.
- W2006083918 isRetracted "false" @default.
- W2006083918 magId "2006083918" @default.
- W2006083918 workType "article" @default.