FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006086985> ?p ?o ?g. }

• W2006086985 endingPage "304" @default.
• W2006086985 startingPage "297" @default.
• W2006086985 abstract "Oxidative stress, overproduction of reactive oxygen species (ROS) in relation to defence mechanisms, is considered to be a major cause of male infertility. For protection against the deleterious effects of ROS, animals have a variety of enzymatic antioxidants that reduce these molecules to less reactive forms. The physiological role of these antioxidants in vivo has been explored extensively through genetic inhibition of gene expression; surprisingly, many of these animals remain fertile in spite of increased oxidative stress. Copper-zinc superoxide dismutase-deficient (Sod1(-/-)) male mice are one such example for which in vivo fertility has been repeatedly reported as normal, although examination of fertility has consisted of simply pairing animals of the same strain and checking for litters. This is a fairly low criterion by which to assess fertility. Herein, we show that Sod1-deficient males have zero fertilisation success in sperm competition trials that pit them against wild-type males of an otherwise identical genetic background and are almost completely infertile when mated singly with females of a different genotype. We also show that various aspects of sperm motility and function are impaired in Sod1-deficient mice. Testing the breeding capabilities of mice under more ecologically relevant conditions and with females of different genotypes may help reveal additional physiological causes of infertility." @default.
• W2006086985 created "2016-06-24" @default.
• W2006086985 creator A5000865551 @default.
• W2006086985 creator A5019669894 @default.
• W2006086985 creator A5067206765 @default.
• W2006086985 creator A5085663664 @default.
• W2006086985 date "2013-10-01" @default.
• W2006086985 modified "2023-10-01" @default.
• W2006086985 title "Copper-zinc superoxide dismutase deficiency impairs sperm motility and in vivo fertility" @default.
• W2006086985 cites W1525464385 @default.
• W2006086985 cites W1684021943 @default.
• W2006086985 cites W1950234730 @default.
• W2006086985 cites W1966657398 @default.
• W2006086985 cites W1968406679 @default.
• W2006086985 cites W1973274511 @default.
• W2006086985 cites W1973466736 @default.
• W2006086985 cites W2003337850 @default.
• W2006086985 cites W2004062071 @default.
• W2006086985 cites W2005853564 @default.
• W2006086985 cites W2006313098 @default.
• W2006086985 cites W2016152398 @default.
• W2006086985 cites W2017474322 @default.
• W2006086985 cites W2019118950 @default.
• W2006086985 cites W2021627123 @default.
• W2006086985 cites W2023323457 @default.
• W2006086985 cites W2038252284 @default.
• W2006086985 cites W2039612834 @default.
• W2006086985 cites W2040751146 @default.
• W2006086985 cites W2042637324 @default.
• W2006086985 cites W2050562344 @default.
• W2006086985 cites W2055014072 @default.
• W2006086985 cites W2056714316 @default.
• W2006086985 cites W2057698095 @default.
• W2006086985 cites W2059317428 @default.
• W2006086985 cites W2072978915 @default.
• W2006086985 cites W2074036761 @default.
• W2006086985 cites W2080774468 @default.
• W2006086985 cites W2080778259 @default.
• W2006086985 cites W2083718982 @default.
• W2006086985 cites W2088060893 @default.
• W2006086985 cites W2091636266 @default.
• W2006086985 cites W2100519951 @default.
• W2006086985 cites W2101228550 @default.
• W2006086985 cites W2104109524 @default.
• W2006086985 cites W2105171996 @default.
• W2006086985 cites W2113007696 @default.
• W2006086985 cites W2114847312 @default.
• W2006086985 cites W2120818752 @default.
• W2006086985 cites W2128234614 @default.
• W2006086985 cites W2129778229 @default.
• W2006086985 cites W2147993424 @default.
• W2006086985 cites W2158173525 @default.
• W2006086985 cites W2167455273 @default.
• W2006086985 cites W2168439614 @default.
• W2006086985 cites W2172018854 @default.
• W2006086985 cites W2211770168 @default.
• W2006086985 cites W4250445065 @default.
• W2006086985 cites W4256604130 @default.
• W2006086985 doi "https://doi.org/10.1530/rep-13-0229" @default.
• W2006086985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23847261" @default.
• W2006086985 hasPublicationYear "2013" @default.
• W2006086985 type Work @default.
• W2006086985 sameAs 2006086985 @default.
• W2006086985 citedByCount "32" @default.
• W2006086985 countsByYear W20060869852014 @default.
• W2006086985 countsByYear W20060869852015 @default.
• W2006086985 countsByYear W20060869852016 @default.
• W2006086985 countsByYear W20060869852018 @default.
• W2006086985 countsByYear W20060869852019 @default.
• W2006086985 countsByYear W20060869852020 @default.
• W2006086985 countsByYear W20060869852021 @default.
• W2006086985 countsByYear W20060869852022 @default.
• W2006086985 countsByYear W20060869852023 @default.
• W2006086985 crossrefType "journal-article" @default.
• W2006086985 hasAuthorship W2006086985A5000865551 @default.
• W2006086985 hasAuthorship W2006086985A5019669894 @default.
• W2006086985 hasAuthorship W2006086985A5067206765 @default.
• W2006086985 hasAuthorship W2006086985A5085663664 @default.
• W2006086985 hasBestOaLocation W20060869851 @default.
• W2006086985 hasConcept C126322002 @default.
• W2006086985 hasConcept C134018914 @default.
• W2006086985 hasConcept C16685009 @default.
• W2006086985 hasConcept C207001950 @default.
• W2006086985 hasConcept C2775838275 @default.
• W2006086985 hasConcept C2776151105 @default.
• W2006086985 hasConcept C2776833037 @default.
• W2006086985 hasConcept C2777338322 @default.
• W2006086985 hasConcept C2777615887 @default.
• W2006086985 hasConcept C2777632594 @default.
• W2006086985 hasConcept C2777688143 @default.
• W2006086985 hasConcept C2779234561 @default.
• W2006086985 hasConcept C2781087480 @default.
• W2006086985 hasConcept C2908647359 @default.
• W2006086985 hasConcept C48349386 @default.
• W2006086985 hasConcept C518429986 @default.
• W2006086985 hasConcept C54355233 @default.
• W2006086985 hasConcept C71924100 @default.
• W2006086985 hasConcept C86803240 @default.

• next