FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006090090> ?p ?o ?g. }

• W2006090090 abstract "The present study was conducted to test the hypothesis that an application of an antiandrogen during pregnancy causes an infantilization of the male offsprings' behaviour later in life. The subjects studied were male guinea pigs whose mothers were either treated with an antiandrogen (flutamide and carrier) or a placebo (carrier only) during pregnancy. The mothers lived in groups of five females and one male. Application of the antiandrogen or the placebo took place on days 30, 32, 34, and 36 of pregnancy, the sensitive phase of foetal CNS sexual differentiation in guinea pigs. After weaning three groups of sons, whose mothers had received the antiandrogen (FT-sons) and five groups of sons, whose mothers had received the placebo (PT-sons) were established. Each group consisted of two males. From their 20th through their 100th day of age, the spontaneous behaviour of the males was recorded in their home cages in 5-day intervals. Additionally, blood samples were collected to determine serum cortisol concentrations. FT-sons and PT-sons did not differ in serum cortisol concentrations. However, distinct differences in behaviour occurred: FT-sons rested significantly longer with bodily contact than PT-sons. Additionally, FT-sons displayed more play-behaviour than PT-sons. These results point to a behavioural infantilization in males prenatally treated with antiandrogen. The behavioural differences between FT- and PT-sons are in accordance with previous studies in which a decrease of serum androgen concentrations in pregnant females living in an unstable social environment [Psychoneuroendocrinology 2001;26:503] and an infantilization of their sons' behaviour was described [Psychoneuroendocrinology 2003;28:67]. Thus, our study supports the hypothesis, that the decrease of androgen concentrations during pregnancy, caused by an unstable social environment, is responsible for the infantilization of the male offsprings' behaviour." @default.
• W2006090090 created "2016-06-24" @default.
• W2006090090 creator A5018125356 @default.
• W2006090090 creator A5024313897 @default.
• W2006090090 creator A5006149526 @default.
• W2006090090 date "2005-03-01" @default.
• W2006090090 modified "2023-10-16" @default.
• W2006090090 title "Application of an antiandrogen during pregnancy infantilizes the male offsprings’ behaviour" @default.
• W2006090090 cites W1503181416 @default.
• W2006090090 cites W1570408419 @default.
• W2006090090 cites W159618920 @default.
• W2006090090 cites W175079480 @default.
• W2006090090 cites W1907617419 @default.
• W2006090090 cites W1964415724 @default.
• W2006090090 cites W1987609643 @default.
• W2006090090 cites W1997423603 @default.
• W2006090090 cites W1998387305 @default.
• W2006090090 cites W1999044770 @default.
• W2006090090 cites W2002206855 @default.
• W2006090090 cites W2006737168 @default.
• W2006090090 cites W2010391369 @default.
• W2006090090 cites W2013096859 @default.
• W2006090090 cites W2028512392 @default.
• W2006090090 cites W2029985888 @default.
• W2006090090 cites W2034129474 @default.
• W2006090090 cites W2034263278 @default.
• W2006090090 cites W2037493305 @default.
• W2006090090 cites W2040459597 @default.
• W2006090090 cites W2041848577 @default.
• W2006090090 cites W2041936691 @default.
• W2006090090 cites W2044296874 @default.
• W2006090090 cites W2052435478 @default.
• W2006090090 cites W2056461989 @default.
• W2006090090 cites W2066550740 @default.
• W2006090090 cites W2066610267 @default.
• W2006090090 cites W2077815818 @default.
• W2006090090 cites W2078104520 @default.
• W2006090090 cites W2079555774 @default.
• W2006090090 cites W2082092388 @default.
• W2006090090 cites W2082642408 @default.
• W2006090090 cites W2087295261 @default.
• W2006090090 cites W2094084162 @default.
• W2006090090 cites W2117715291 @default.
• W2006090090 cites W574677483 @default.
• W2006090090 doi "https://doi.org/10.1016/j.bbr.2004.08.009" @default.
• W2006090090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15680197" @default.
• W2006090090 hasPublicationYear "2005" @default.
• W2006090090 type Work @default.
• W2006090090 sameAs 2006090090 @default.
• W2006090090 citedByCount "5" @default.
• W2006090090 countsByYear W20060900902012 @default.
• W2006090090 countsByYear W20060900902013 @default.
• W2006090090 countsByYear W20060900902018 @default.
• W2006090090 crossrefType "journal-article" @default.
• W2006090090 hasAuthorship W2006090090A5006149526 @default.
• W2006090090 hasAuthorship W2006090090A5018125356 @default.
• W2006090090 hasAuthorship W2006090090A5024313897 @default.
• W2006090090 hasConcept C121608353 @default.
• W2006090090 hasConcept C126322002 @default.
• W2006090090 hasConcept C134018914 @default.
• W2006090090 hasConcept C142724271 @default.
• W2006090090 hasConcept C15744967 @default.
• W2006090090 hasConcept C204787440 @default.
• W2006090090 hasConcept C27081682 @default.
• W2006090090 hasConcept C2777911890 @default.
• W2006090090 hasConcept C2778313021 @default.
• W2006090090 hasConcept C2779234561 @default.
• W2006090090 hasConcept C2779322244 @default.
• W2006090090 hasConcept C2780192828 @default.
• W2006090090 hasConcept C46973012 @default.
• W2006090090 hasConcept C54355233 @default.
• W2006090090 hasConcept C61367390 @default.
• W2006090090 hasConcept C71315377 @default.
• W2006090090 hasConcept C71924100 @default.
• W2006090090 hasConcept C86803240 @default.
• W2006090090 hasConceptScore W2006090090C121608353 @default.
• W2006090090 hasConceptScore W2006090090C126322002 @default.
• W2006090090 hasConceptScore W2006090090C134018914 @default.
• W2006090090 hasConceptScore W2006090090C142724271 @default.
• W2006090090 hasConceptScore W2006090090C15744967 @default.
• W2006090090 hasConceptScore W2006090090C204787440 @default.
• W2006090090 hasConceptScore W2006090090C27081682 @default.
• W2006090090 hasConceptScore W2006090090C2777911890 @default.
• W2006090090 hasConceptScore W2006090090C2778313021 @default.
• W2006090090 hasConceptScore W2006090090C2779234561 @default.
• W2006090090 hasConceptScore W2006090090C2779322244 @default.
• W2006090090 hasConceptScore W2006090090C2780192828 @default.
• W2006090090 hasConceptScore W2006090090C46973012 @default.
• W2006090090 hasConceptScore W2006090090C54355233 @default.
• W2006090090 hasConceptScore W2006090090C61367390 @default.
• W2006090090 hasConceptScore W2006090090C71315377 @default.
• W2006090090 hasConceptScore W2006090090C71924100 @default.
• W2006090090 hasConceptScore W2006090090C86803240 @default.
• W2006090090 hasLocation W20060900901 @default.
• W2006090090 hasLocation W20060900902 @default.
• W2006090090 hasOpenAccess W2006090090 @default.
• W2006090090 hasPrimaryLocation W20060900901 @default.
• W2006090090 hasRelatedWork W1967171675 @default.
• W2006090090 hasRelatedWork W1973860147 @default.
• W2006090090 hasRelatedWork W1976294933 @default.

• next