Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006132005> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2006132005 endingPage "251" @default.
- W2006132005 startingPage "245" @default.
- W2006132005 abstract "Cumulative damage in mitochondria by reactive oxygen species is thought to result in a decrease in mitochondrial respiratory function and to contribute to the age-related decline in the physiological function of organisms. The mitochondrial genome is also subjected to damage with age through deletions. The accumulation of deleted mitochondrial DNA (mtDNA) has been observed in various animals, but still remains unclear in insects. We examined the accumulation of deleted mtDNA in D. melanogaster at various ages from larvae to 65-day-old adults. When DNA extracted from whole bodies was examined by PCR and Southern hybridization, the age-related accumulation of deletions was not clear. However, when the accumulation of deleted mtDNA with age was examined separately in three parts of the body (head, thorax and abdomen), deleted mtDNA signals were detected more frequently in the thorax and the accumulation was age-dependent. Three of the deleted mtDNA were cloned, and the breakpoints of the deletions were identified. These results strongly suggest that deleted mtDNA accumulates in Drosophila with age in a tissue-specific manner." @default.
- W2006132005 created "2016-06-24" @default.
- W2006132005 creator A5003085424 @default.
- W2006132005 creator A5012955338 @default.
- W2006132005 creator A5046514763 @default.
- W2006132005 date "2003-01-01" @default.
- W2006132005 modified "2023-09-25" @default.
- W2006132005 title "Accumulation of deleted mitochondrial DNA in aging Drosophila melanogaster." @default.
- W2006132005 cites W1971104692 @default.
- W2006132005 cites W1973851166 @default.
- W2006132005 cites W1994496497 @default.
- W2006132005 cites W1998401548 @default.
- W2006132005 cites W2015411189 @default.
- W2006132005 cites W2029269538 @default.
- W2006132005 cites W2029282672 @default.
- W2006132005 cites W2034734284 @default.
- W2006132005 cites W2037717843 @default.
- W2006132005 cites W2039294540 @default.
- W2006132005 cites W2046259613 @default.
- W2006132005 cites W2052341466 @default.
- W2006132005 cites W2057162464 @default.
- W2006132005 cites W2064596113 @default.
- W2006132005 cites W2064655402 @default.
- W2006132005 cites W2066016132 @default.
- W2006132005 cites W2067193380 @default.
- W2006132005 cites W2068568687 @default.
- W2006132005 cites W2069602367 @default.
- W2006132005 cites W2074303856 @default.
- W2006132005 cites W2083109098 @default.
- W2006132005 cites W2087432006 @default.
- W2006132005 cites W2126474158 @default.
- W2006132005 cites W2152556843 @default.
- W2006132005 cites W2315512556 @default.
- W2006132005 doi "https://doi.org/10.1266/ggs.78.245" @default.
- W2006132005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12893966" @default.
- W2006132005 hasPublicationYear "2003" @default.
- W2006132005 type Work @default.
- W2006132005 sameAs 2006132005 @default.
- W2006132005 citedByCount "43" @default.
- W2006132005 countsByYear W20061320052012 @default.
- W2006132005 countsByYear W20061320052013 @default.
- W2006132005 countsByYear W20061320052014 @default.
- W2006132005 countsByYear W20061320052015 @default.
- W2006132005 countsByYear W20061320052016 @default.
- W2006132005 countsByYear W20061320052018 @default.
- W2006132005 countsByYear W20061320052020 @default.
- W2006132005 countsByYear W20061320052022 @default.
- W2006132005 crossrefType "journal-article" @default.
- W2006132005 hasAuthorship W2006132005A5003085424 @default.
- W2006132005 hasAuthorship W2006132005A5012955338 @default.
- W2006132005 hasAuthorship W2006132005A5046514763 @default.
- W2006132005 hasBestOaLocation W20061320051 @default.
- W2006132005 hasConcept C104317684 @default.
- W2006132005 hasConcept C115960442 @default.
- W2006132005 hasConcept C141231307 @default.
- W2006132005 hasConcept C24586158 @default.
- W2006132005 hasConcept C2780104201 @default.
- W2006132005 hasConcept C28859421 @default.
- W2006132005 hasConcept C54355233 @default.
- W2006132005 hasConcept C552990157 @default.
- W2006132005 hasConcept C86803240 @default.
- W2006132005 hasConceptScore W2006132005C104317684 @default.
- W2006132005 hasConceptScore W2006132005C115960442 @default.
- W2006132005 hasConceptScore W2006132005C141231307 @default.
- W2006132005 hasConceptScore W2006132005C24586158 @default.
- W2006132005 hasConceptScore W2006132005C2780104201 @default.
- W2006132005 hasConceptScore W2006132005C28859421 @default.
- W2006132005 hasConceptScore W2006132005C54355233 @default.
- W2006132005 hasConceptScore W2006132005C552990157 @default.
- W2006132005 hasConceptScore W2006132005C86803240 @default.
- W2006132005 hasIssue "3" @default.
- W2006132005 hasLocation W20061320051 @default.
- W2006132005 hasLocation W20061320052 @default.
- W2006132005 hasOpenAccess W2006132005 @default.
- W2006132005 hasPrimaryLocation W20061320051 @default.
- W2006132005 hasRelatedWork W132149934 @default.
- W2006132005 hasRelatedWork W1981511762 @default.
- W2006132005 hasRelatedWork W2035022637 @default.
- W2006132005 hasRelatedWork W2037542399 @default.
- W2006132005 hasRelatedWork W2094865811 @default.
- W2006132005 hasRelatedWork W2106182899 @default.
- W2006132005 hasRelatedWork W2142669469 @default.
- W2006132005 hasRelatedWork W2235815306 @default.
- W2006132005 hasRelatedWork W2376017112 @default.
- W2006132005 hasRelatedWork W4307583996 @default.
- W2006132005 hasVolume "78" @default.
- W2006132005 isParatext "false" @default.
- W2006132005 isRetracted "false" @default.
- W2006132005 magId "2006132005" @default.
- W2006132005 workType "article" @default.