Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006134342> ?p ?o ?g. }
- W2006134342 endingPage "768" @default.
- W2006134342 startingPage "725" @default.
- W2006134342 abstract "We present a detailed analysis of the protein structures in the 30 S ribosomal subunit from Thermus thermophilus, and their interactions with 16 S RNA based on a crystal structure at 3.05 A resolution. With 20 different polypeptide chains, the 30 S subunit adds significantly to our data base of RNA structure and protein-RNA interactions. In addition to globular domains, many of the proteins have long, extended regions, either in the termini or in internal loops, which make extensive contact to the RNA component and are involved in stabilizing RNA tertiary structure. Many ribosomal proteins share similar alpha+beta sandwich folds, but we show that the topology of this domain varies considerably, as do the ways in which the proteins interact with RNA. Analysis of the protein-RNA interactions in the context of ribosomal assembly shows that the primary binders are globular proteins that bind at RNA multihelix junctions, whereas proteins with long extensions assemble later. We attempt to correlate the structure with a large body of biochemical and genetic data on the 30 S subunit." @default.
- W2006134342 created "2016-06-24" @default.
- W2006134342 creator A5012194078 @default.
- W2006134342 creator A5024758557 @default.
- W2006134342 creator A5032913188 @default.
- W2006134342 creator A5073572588 @default.
- W2006134342 creator A5086176987 @default.
- W2006134342 date "2002-02-01" @default.
- W2006134342 modified "2023-10-10" @default.
- W2006134342 title "Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA" @default.
- W2006134342 cites W10876090 @default.
- W2006134342 cites W123685430 @default.
- W2006134342 cites W1480869377 @default.
- W2006134342 cites W1483678770 @default.
- W2006134342 cites W1492288245 @default.
- W2006134342 cites W1496169743 @default.
- W2006134342 cites W1508676160 @default.
- W2006134342 cites W151718112 @default.
- W2006134342 cites W1522104342 @default.
- W2006134342 cites W1551816574 @default.
- W2006134342 cites W1554284704 @default.
- W2006134342 cites W1564216598 @default.
- W2006134342 cites W1568741842 @default.
- W2006134342 cites W1595347220 @default.
- W2006134342 cites W1604210099 @default.
- W2006134342 cites W1746621838 @default.
- W2006134342 cites W1870805240 @default.
- W2006134342 cites W1967024927 @default.
- W2006134342 cites W1968052992 @default.
- W2006134342 cites W1968611249 @default.
- W2006134342 cites W1970140683 @default.
- W2006134342 cites W1971191777 @default.
- W2006134342 cites W1971436630 @default.
- W2006134342 cites W1972413131 @default.
- W2006134342 cites W1978380017 @default.
- W2006134342 cites W1983534198 @default.
- W2006134342 cites W1983887979 @default.
- W2006134342 cites W1988247823 @default.
- W2006134342 cites W1989157362 @default.
- W2006134342 cites W1990077400 @default.
- W2006134342 cites W1990246459 @default.
- W2006134342 cites W1990285498 @default.
- W2006134342 cites W1991658734 @default.
- W2006134342 cites W1991697764 @default.
- W2006134342 cites W1992326245 @default.
- W2006134342 cites W1993287196 @default.
- W2006134342 cites W1993818423 @default.
- W2006134342 cites W1993926172 @default.
- W2006134342 cites W1995003025 @default.
- W2006134342 cites W1995397677 @default.
- W2006134342 cites W1995635512 @default.
- W2006134342 cites W1996068101 @default.
- W2006134342 cites W1996995284 @default.
- W2006134342 cites W1998116088 @default.
- W2006134342 cites W1998336158 @default.
- W2006134342 cites W1998697653 @default.
- W2006134342 cites W2000088431 @default.
- W2006134342 cites W2001422120 @default.
- W2006134342 cites W2001641653 @default.
- W2006134342 cites W2001649652 @default.
- W2006134342 cites W2002195659 @default.
- W2006134342 cites W2006461920 @default.
- W2006134342 cites W2007117841 @default.
- W2006134342 cites W2008570049 @default.
- W2006134342 cites W2012879549 @default.
- W2006134342 cites W2014562830 @default.
- W2006134342 cites W2014860689 @default.
- W2006134342 cites W2016606288 @default.
- W2006134342 cites W2019160551 @default.
- W2006134342 cites W2027369938 @default.
- W2006134342 cites W2029314164 @default.
- W2006134342 cites W2029627196 @default.
- W2006134342 cites W2029842408 @default.
- W2006134342 cites W2031013931 @default.
- W2006134342 cites W2032042692 @default.
- W2006134342 cites W2034767282 @default.
- W2006134342 cites W2034890717 @default.
- W2006134342 cites W2036784493 @default.
- W2006134342 cites W2037778781 @default.
- W2006134342 cites W2041177864 @default.
- W2006134342 cites W2041815688 @default.
- W2006134342 cites W2041958465 @default.
- W2006134342 cites W2042343001 @default.
- W2006134342 cites W2043017556 @default.
- W2006134342 cites W2043741353 @default.
- W2006134342 cites W2044220084 @default.
- W2006134342 cites W2044405979 @default.
- W2006134342 cites W2044512234 @default.
- W2006134342 cites W2044775131 @default.
- W2006134342 cites W2045099180 @default.
- W2006134342 cites W2045434091 @default.
- W2006134342 cites W2046788335 @default.
- W2006134342 cites W2057183734 @default.
- W2006134342 cites W2059622953 @default.
- W2006134342 cites W2063798430 @default.
- W2006134342 cites W2066398640 @default.
- W2006134342 cites W2066503489 @default.
- W2006134342 cites W2066965142 @default.